Fluorination reactions are an important class of organic synthesis. Fluorine
is a highly electronegative atom; thus, it has dual characteristics, such as being basic
and nucleophilic in nature which produces various products. In this chapter, we have
discussed the recent development of fluorination methods by using various phase
transfer catalysts. The catalyst plays a significant role in aliphatic nucleophilic
fluorination. The various tasks of specific tailor-made ionic liquids are developed and
used for fluorination reactions. Ionic liquid catalyst is immobilized, covalently
bonded on solid or liquid support to improve the catalytic efficiency in the reactions.
Keywords: Aliphatic nucleophilic substitution, Catalyst, Electrophilic,
Fluorination, Halogenations, Ionic Liquids, Methodologies, Organic reactions.