Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have emerged as
alternate dosage forms for patients who cannot swallow or who should not swallow or
who refuse to swallow conventional tablets/capsules and liquid formulations. FDDFs
include Fast Dissolving/Disintegrating Tablets (FDTs), Fast Dissolving/Disintegrating
Oral Films (FDOFs), Fast Dissolving/Disintegrating Capsules (FDCs), Fast
Dissolving/Disintegrating Pellets (FDPs), etc. These dosage forms dissolve/disintegrate
quickly, when placed on tongue, resulting in solution/suspension, which can be
swallowed easily and hence do not require water for their oral ingestion. This chapter
introduces FDDFs rationale, their brief history, regulatory/pharmacopoeial aspects,
advantages/disadvantages and their market potential.
Keywords: Absorption, Capsule, Dysphagia, FDT, Film, Freeze drying, Geriatric,
Granule, Mini tablet, Nausea, ODT, Orodispersible, Paediatric, Parkinsonism,
Pellet, Pharmacopoeia, Psychotic, Quality of life, Tablet, Travellers.
