Abstract
Recently, there has been wide interest in compounds containing the oxadiazole scaffold because of their unique chemical structure and their broad spectrum of biological properties. This review provides readers with an overview of the main synthetic methodologies for oxadiazoles and of their broad spectrum of pharmacological activities such as, anti-microbial, anti-fungal activity, antiviral, anti-tubercular, anti-inflammatory, anti-convulsant, anti-angiogenic, anti-proliferative, analgesic, anti-oedema and in alzheimer activity, which were reported over the past years.
Keywords: Anti-bacterial, anticonvulsant, antifungal, anti-inflammatory, analgesic, anticancer, oxadiazole.
Mini-Reviews in Medicinal Chemistry
Title:Synthesis and Biological Activities of Oxadiazole Derivatives: A Review
Volume: 16 Issue: 10
Author(s): Ankur Vaidya, Shweta Jain, Priyanka Jain, Prachi Jain, Nidhi Tiwari, Roshni Jain, Rashi Jain, Abhishek K. Jain and Ram K. Agrawal
Affiliation:
Keywords: Anti-bacterial, anticonvulsant, antifungal, anti-inflammatory, analgesic, anticancer, oxadiazole.
Abstract: Recently, there has been wide interest in compounds containing the oxadiazole scaffold because of their unique chemical structure and their broad spectrum of biological properties. This review provides readers with an overview of the main synthetic methodologies for oxadiazoles and of their broad spectrum of pharmacological activities such as, anti-microbial, anti-fungal activity, antiviral, anti-tubercular, anti-inflammatory, anti-convulsant, anti-angiogenic, anti-proliferative, analgesic, anti-oedema and in alzheimer activity, which were reported over the past years.
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Vaidya Ankur, Jain Shweta, Jain Priyanka, Jain Prachi, Tiwari Nidhi, Jain Roshni, Jain Rashi, K. Jain Abhishek and K. Agrawal Ram, Synthesis and Biological Activities of Oxadiazole Derivatives: A Review, Mini-Reviews in Medicinal Chemistry 2016; 16 (10) . https://dx.doi.org/10.2174/1389557516666160211120835
DOI https://dx.doi.org/10.2174/1389557516666160211120835 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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