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Protein & Peptide Letters

Volume 28, 12 Issues, 2021
ISSN: 1875-5305 (Online)
ISSN: 0929-8665 (Print)
This journal supports open access

Aims & Scope

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations.

Protein & Peptide Letters focuses on:


  • Structure Studies
  • Advances in Recombinant Expression
  • Drug Design
  • Chemical Synthesis
  • Function
  • Pharmacology
  • Enzymology
  • Conformational Analysis
  • Immunology
  • Biotechnology
  • Protein Engineering
  • Protein Folding
  • Sequencing
  • Molecular Recognition
  • Purification and Analysis

Protein & Peptide Letters

,

Volume 28

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Number 2



Biography   Open Access



Review Article



Research Article



Research Article

Molecular Insights into Zn2+ Inhibition of the Antibacterial Endopeptidase Lysostaphin from Staphylococcus simulans

, 28(2): 140 - 148

Ke Chen, Suvash Chandra Ojha, Chompounoot Imtong, Aung Khine Linn, Hui-Chun Li, Charoensri Thonabulsombat and Chanan Angsuthanasombat*


DOI: 10.2174/0929866527666200613221359


Research Article

Bifunctional Inhibitors from Capsicum chinense Seeds with Antimicrobial Activity and Specific Mechanism of Action Against Phytopathogenic Fungi

, 28(2): 149 - 163

Marciele Souza da Silva, Valdirene Moreira Gomes*, Gabriel Bonan Taveira, Layrana de Azevedo dos Santos, Álan C. Maracahipes, Rosana Rodrigues, André de Oliveira Carvalho, Katia Valevski S. Fernandes and Antonia Elenir A. Oliveira


DOI: 10.2174/0929866527666200617124221






Research Article



Protein & Peptide Letters, Volume 28 (2021) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Protein & Peptide Letters, Volume 28 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Fusion Expression and Fibrinolytic Activity of rPA/SP-B


Yi-Shan Tang, Xiao-Jun Zhang, Wan-Neng Wang*, Ting Wang, Wu-Long Cao, Qiu-Han Zhang and Fu Chen


DOI: 10.2174/0929866528666210301151302
View Abstract View on PubMed




Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19


Amir Hossein Kheirkhah, Seyed Hossein Shahcheraghi, Malihe lotfi, Marzieh lotfi*, Sanaz Raeisi and Zulfiqar Mirani*


DOI: 10.2174/0929866528666210222150347
View Abstract View on PubMed


Hepatotoxic Effect of Lafoensia pacari A. St. Hil. (Lythraceae) on a Diet-Induced Obese Mice Model


Natália Gonçalves Ribeiro, Fabio Ribeiro dos Santos, Janaína Ribeiro Oliveira, Amanda Souto Machado, Deborah de Faria Lelis, Alfredo Maurício Batista de Paula, André Luis Sena Guimarães, Lucyana Conceição Farias and Sérgio Henrique Sousa Santos*


DOI: 10.2174/0929866528666210127151803
View Abstract View on PubMed



Site-Selective, Chemical Modification of Protein at Aromatic Side Chain and Their Emergent Applications


Arnab Chowdhury, Saurav Chatterjee, Akumlong Pongen, Dhanjit Sarania, Nitesh Mani Tripathi and Anupam Bandyopadhyay*


DOI: 10.2174/0929866528666210129152535
View Abstract View on PubMed


Evolution and Structure of API5 and Its Roles in Anti-apoptosis


Meishan Chen, Weiwei Wu, Dongwu Liu, Yanhua Lv, Hongkuan Den, Sijia Gao, Yaqi Gu, Mujie Huang, Xiao Guo, Baohua Liu, Bosheng Zhao and Qiuxiang Pang*


DOI: 10.2174/0929866527999201211195551
View Abstract View on PubMed



Pathways Related to the Anti-Cancer Effects of Metabolites Derived from Cerrado Biome Native Plants: An Update and Bioinformatics Analysis on Oral Squamous Cell Carcinoma


Guilherme Machado Xavier, André Luiz Sena Guimarães*, Carlos Alberto de Carvalho Fraga, Talita Antunes Guimarães, Marcela Gonçalves de Souza, Kimberly Marie Jones and Lucyana Conceição Farias


DOI: 10.2174/0929866527999201209221012
View Abstract View on PubMed


Abstracts Ahead of Print

Database Study on the Expression and Purification of Membrane Proteins


Chen-Yan china Zhang *, Shi-Qi Zhao , Shi-Long Zhang , Li-Heng Luo, Ding-Chang Liu, Wei-Hang Ding, Dong-Jie Fu, Xu-Dong Deng and Da-Chuan Yin


DOI: 10.2174/0929866528666210415120234
View Abstract



Strategy for the enrichment of protein biomarkers from diverse bacterial select agents


Sasikumar Sabna, Dev Vrat Kamboj, Ravi Bhushan Kumar, Prabhakar Babele, Sakshi Rajoria, Mahendra Kumar Gupta and Syed Imteyaz Alam*


DOI: 10.2174/0929866528666210405160131
View Abstract



Integration of OMICS Technologies for Crop Improvement


Amna Faryal, Faiza Aziz, Jannat Tahir, Maimoona Kousar, Muhammad Qasim* and Aysha Shamim


DOI: 10.2174/0929866528666210310161207
View Abstract



Potential Application of CRISPR/Cas9 System to Engineer Abiotic Stress Tolerance in Plants


Temoor Ahmed, Muhammad Shahid*, Muhammad Noman, Sher Muhammad, Muhammad Tahir ul Qamar, Md. Arshad Ali, Awais Maqsood, Rahila Hafeez, Solabomi Olaitan Ogunyemi and Bin Li


DOI: 10.2174/0929866528666210218220138
View Abstract




Genome-Wide Association Study for major Biofuel Traits in Sorghum Using Minicore Collection


Laavanya Rayaprolu, Sivasubramani Selvanayagam, D Manohar Rao Daggu, Rajeev Gupta, Roma Rani Das, Abhishek Rathore, Prasad Gandham, KNS Usha Kiranmayee, Santosh P Deshpande* and Ashok Kumar Are*


DOI: 10.2174/0929866528666210215141243
View Abstract


Published Contents

Editor's Choice

Expression, Solubilization, Refolding and Final Purification of Recombinant Proteins as Expressed in the form of “Classical Inclusion Bodies” in E. coli

, 2021; 28(2): 122 - 130

Mohammad Sadegh Hashemzadeh*, Mozafar Mohammadi, Hadi Esmaeili Gouvarchin Ghaleh, Mojtaba Sharti, Ali Choopani and Amulya Kumar Panda


DOI: 10.2174/0929866527999200729182831



Establishment of Method for the Determination of Aggregated α-Synuclein in DLB Patient Using RT-QuIC Assay

, 2021; 28(1): 115 - 120

Seok-Joo Park, Yun-Jung Lee, Jeong-Ho Park, Hyoung-Tae Jin, Myoung-Ju Choi, Cha-Gyun Jung, Hiroyasu Akatsu, Eun-Kyoung Choi and Yong-Sun Kim*


DOI: 10.2174/0929866527666200420105352



Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions

, 2020; 27(12): 1204 - 1230

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555




Development of Cell Penetrating Peptides for Effective Delivery of Recombinant Factors into Target Cells

, 2020; 27(11): 1092 - 1101

Ubashini Vijakumaran, Fazlina Nordin*, Zariyantey Abdul Hamid, Maha Abdullah and Tye Gee Jun


DOI: 10.2174/0929866527666200525164135



CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy: A Review

, 2020; 27(10): 931 - 944

Fatima Akram*, Ikram ul Haq, Zeeshan Ahmed, Hamza Khan and Muhammad Shrafat Ali


DOI: 10.2174/0929866527666200407112432



Neuropeptide Y Induces Cardiomyocyte Hypertrophy via Attenuating miR-29a-3p in Neonatal Rat Cardiomyocytes

, 2020; 27(9): 878 - 887

Yuxin Xie, Jun Hu, Xincai Zhang, Chunxiao Li, Yuanyi Zuo, Shining Xie, Zhixiang Zhang and Shaohua Zhu*


DOI: 10.2174/0929866527666200416144459



Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials

, 2020; 27(8): 688 - 697

Yu Chen, Kai Tao, Wei Ji, Pandeeswar Makam, Sigal Rencus-Lazar and Ehud Gazit*


DOI: 10.2174/0929866527666200212123542



Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer Patients

, 2020; 27(7): 658 - 673

Ayesha Zafar, Maryum Jabbar, Yasmeen Manzoor, Huma Gulzar, Shahzad Gul Hassan, Muniba Anum Nazir, Ain-ul-Haq, Ghazala Mustafa, Romana Sahar, Aqeel Masood, Ahtesham Iqbal, Mulazim Hussain and Murtaza Hasan*


DOI: 10.2174/0929866527666200110155609



The Renin-Angiotensin System in Huntington’s Disease: Villain or Hero?

, 2020; 27(6): 456 - 462

Thatiane C.G. Machado, Cristina Guatimosim* and Lucas M. Kangussu*


DOI: 10.2174/0929866527666200110154523



Open Access Articles


Expression, Purification and Characterization of Recombinant Human Coagulation Factor XIIIa in Pichia Pastoris

, 2021; 28(1): 55 - 62

Linyan Cheng, Ting Zhang, Yuchang Fei, Hao Shen, Hui Huang, Jin Chen, Bin Xu* and Jian Xu*




Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?

, 2020; 27(12): 1186 - 1191

Giuseppe Grande*, Domenico Milardi, Silvia Baroni, Andrea Urbani and Alfredo Pontecorvi




The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence

, 2020; 27(6): 463 - 475

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*




miR-146a-5p Regulated Cell Proliferation and Apoptosis by Targeting SMAD3 and SMAD4

, 2020; 27(5): 411 - 418

Meiyu Qiu, Tao Li, Binhu Wang, Hongbin Gong and Tao Huang*





NMAAP1 Maintains M1 Phenotype in Macrophages Through Binding to IP3R and Activating Calcium-related Signaling Pathways

, 2019; 26(10): 751 - 757

Qihui Liu, Pei Zhu, Shanshan Liu, Mengyan Tang, Yuanxin Wang, Yuan Tian, Zheng Jin, Dong Li and Dongmei Yan*






Differential S-acylation of Enveloped Viruses

, 2019; 26(8): 588 - 600

Larisa V. Kordyukova*, Marina V. Serebryakova, Vladislav V. Khrustalev and Michael Veit





Little Antimicrobial Peptides with Big Therapeutic Roles

, 2019; 26(8): 564 - 578

Dan Zhang, Yu He, Yang Ye, Yanni Ma, Peng Zhang, Hongxia Zhu, Ningzhi Xu and Shufang Liang*





Dimerization of Antimicrobial Peptides: A Promising Strategy to Enhance Antimicrobial Peptide Activity

, 2019; 26(2): 98 - 107

Esteban N. Lorenzon, Julia P. Piccoli, Norival A. Santos-Filho and Eduardo M. Cilli*






Most Cited Articles

Review Article

Clinical applications of antimicrobial peptides (AMPs): Where do we stand now?

, 2020; 27(2): 120-134.

Mithoor Divyashree, Madhu K. Mani, Dhanasekhar Reddy, Ranjith Kumavath*, Preetam Ghosh, Vasco Azevedo and Debmalya Barh*


DOI: 10.2174/0929866526666190925152957


Research Article

Characterizing the binding of angiotensin converting enzyme i inhibitory peptide to human hemoglobin: Influence of electromagnetic fields

, 2020; 27(10): 1007-1021.

Farzaneh Sadeghzadeh, Amir Arsalan Entezari, Kiana Behzadian, Kimia Habibi, Zeinab Amiri-Tehranizadeh*, Ahmad Asoodeh, Mohammad Reza Saberi and Jamshidkhan Chamani*


DOI: 10.2174/1871530320666200425203636


Review Article (Mini-Review)

Mini review on antimicrobial peptides, sources, mechanism and recent applications

, 2020; 27(1): 4-16.

Jaspreet Kaur Boparai and Pushpender Kumar Sharma*


DOI: 10.2174/0929866526666190822165812


Review Article

The renin-angiotensin system and the cerebrovascular diseases: Experimental and clinical evidence

, 2020; 27(6): 463-475.

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929866527666191218091823



Review Article

Recombinant protein production in microalgae: Emerging trends

, 2020; 27(2): 105-110.

Niaz Ahmad*, Muhammad Aamer Mehmood and Sana Malik


DOI: 10.2174/0929866526666191014124855


Research Article

Diosmetin induces apoptosis by downregulating akt phosphorylation via p53 activation in human renal carcinoma achn cells

, 2020; 27(10): 1022-1028.

Mingning Qiu, Jie Liu, Yongxia Su, Rong Guo, Baoyu Zhao* and Jianjun Liu*


DOI: 10.2174/0929866527666200330172646


Review Article

Crispr-cas9, a promising therapeutic tool for cancer therapy: A review

, 2020; 27(10): 931-944.

Fatima Akram*, Ikram ul Haq, Zeeshan Ahmed, Hamza Khan and Muhammad Shrafat Ali


DOI: 10.2174/0929866527666200407112432


Review Article (Mini-Review)

Adipokines: A rainbow of proteins with metabolic and endocrine functions

, 2020; 27(12): 1204-1230.

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555


Systematic Review Article

Renin-angiotensin-aldosterone system and migraine: A systematic review of human studies

, 2020; 27(6): 512-519.

Karina Lúcia Moreira Sassi, Laís Bhering Martins, Aline Silva de Miranda and Antonio Lucio Teixeira*


DOI: 10.2174/0929866527666200129160136


Review Article (Mini-Review)

Exploring the evidence implicating the renin-angiotensin system (RAS) in the physiopathology of mood disorders

, 2020; 27(6): 449-455.

Satyajit Mohite, Marsal Sanches and Antonio L. Teixeira*


DOI: 10.2174/0929866527666191223144000


Review Article

Renin-angiotensin system and Alzheimer’s disease pathophysiology: From the potential interactions to therapeutic perspectives

, 2020; 27(6): 484-511.

Victor Teatini Ribeiro *, Leonardo Cruz de Souza and Ana Cristina Simões e Silva


DOI: 10.2174/0929866527666191230103739


Research Article

Antimicrobial and antibiofilm activity of Lys-[Trp6]hy-a1 combined with ciprofloxacin against gram-negative bacteria

, 2020; 27(11): 1124-1131.

Victor Alves Carneiro*, Simone Torres de Oliveira, Rondinely Lima Silva, Humberlania de Sousa Duarte, Maria Laína Silva, Maria Nágila Carneiro Matos, Rafaela Mesquita Bastos Cavalcante, Ciro Siqueira Figueira, Esteban Nicolás Lorenzón, Eduardo Maffud Cilli and Rodrigo Maranguape Silva da Cunha


DOI: 10.2174/0929866527666200416145549


Research Article

Aloperine induces apoptosis by a reactive oxygen species activation mechanism in human ovarian cancer cells

, 2020; 27(9): 860-869.

Mingning Qiu, Jie Liu, Yongxia Su, Jianjun Liu, Chenchen Wu and Baoyu Zhao*


DOI: 10.2174/0929866527666200320094313


Review Article

Neuropsychiatric properties of the ace2/ang-(1-7)/mas pathway: A brief review

, 2020; 27(6): 476-483.

Leonardo Augusto de Melo and Ana Flávia Almeida-Santos*


DOI: 10.2174/0929866527666191223143230



Most Accessed Articles

Mechanisms of Lignin-Degrading Enzymes

, 2020; 27(7): 574-581.

Jianlong Xiao, Sitong Zhang* and Guang Chen*


DOI: 10.2174/0929866527666191223141756




Protein Markers in Osteoporosis

, 2020; 27(12): 1253-1259.

Teresa Porcelli, Letizia Pezzaioli, Andrea Delbarba, Filippo Maffezzoni, Carlo Cappelli and Alberto Ferlin*


DOI: 10.2174/1871530320666200425204634



CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy: A Review

, 2020; 27(10): 931-944.

Fatima Akram*, Ikram ul Haq, Zeeshan Ahmed, Hamza Khan and Muhammad Shrafat Ali


DOI: 10.2174/0929866527666200407112432


Triple-A Syndrome (TAS): An In-Depth Overview on Genetic and Phenotype Heterogeneity

, 2020; 27(12): 1192-1203.

Gabriele Pogliaghi, Biagio Cangiano, Paolo Duminuco, Valeria Vezzoli* and Marco Bonomi


DOI: 10.2174/0929866527666200613215449



Expression, Purification and Characterization of Recombinant Human Coagulation Factor XIIIa in Pichia Pastoris

, 2021; 28(1): 55-62.

Linyan Cheng, Ting Zhang, Yuchang Fei, Hao Shen, Hui Huang, Jin Chen, Bin Xu* and Jian Xu*


DOI: 10.2174/0929866527666200625203240


Separation of the Epitopes in a Multi-Epitope Chimera: Helical or Flexible Linkers

, 2020; 27(7): 604-613.

Mona Kabiri, Mohsen Tafaghodi, Mohammad Reza Saberi, Maliheh Moghadam, Seyed Abdolrahim Rezaee and Mojtaba Sankian*


DOI: 10.2174/0929866526666191112124602


Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer Patients

, 2020; 27(7): 658-673.

Ayesha Zafar, Maryum Jabbar, Yasmeen Manzoor, Huma Gulzar, Shahzad Gul Hassan, Muniba Anum Nazir, Ain-ul-Haq, Ghazala Mustafa, Romana Sahar, Aqeel Masood, Ahtesham Iqbal, Mulazim Hussain and Murtaza Hasan*


DOI: 10.2174/0929866527666200110155609


The Role of Growth Hormone Receptor Isoforms and Their Effects in Bone Metabolism and Skeletal Fragility

, 2020; 27(12): 1260-1267.

Sabrina Chiloiro*, Federica Mirra, Donfrancesco Federico, Antonella Giampietro, Felicia Visconti, Laura Rossi, Alfredo Pontecorvi, Laura De Marinis and Antonio Bianchi


DOI: 10.2174/0929866527666200616151105




Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions

, 2020; 27(12): 1204-1230.

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555




Editor-in-Chief

graphic
Prof. Ben M. Dunn
Department of Biochemistry and Molecular Biology
University of Florida
College of Medicine
Gainesville, FL
(USA)
Email: bdunn@ufl.eduBiography
View Full Editorial Board

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Journal History

Protein & Peptide Letters was introduced in 2001 with the assistance of Dr. Ben M. Dunn, who is the current Editor-in-Chief serving since 2001.
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