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Protein & Peptide Letters

Volume 28, 12 Issues, 2021
ISSN: 1875-5305 (Online)
ISSN: 0929-8665 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations.

Protein & Peptide Letters focuses on:


  • Structure Studies
  • Advances in Recombinant Expression
  • Drug Design
  • Chemical Synthesis
  • Function
  • Pharmacology
  • Enzymology
  • Conformational Analysis
  • Immunology
  • Biotechnology
  • Protein Engineering
  • Protein Folding
  • Sequencing
  • Molecular Recognition
  • Purification and Analysis

Protein & Peptide Letters

,

Volume 27

-

Number 12



Editorial   Open Access



Letter to the Editor

Novel Insights on the Role of the Human Sperm Proteome

, 27(12): 1181 - 1185

Rossella Cannarella, Rosita A. Condorelli*, Aldo E. Calogero and Sandro La Vignera


DOI: 10.2174/0929866527666200505215921


Review Article (Mini-Review)   Open Access



Review Article (Mini-Review)



Review Article (Mini-Review)

Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions

, 27(12): 1204 - 1230

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555


Review Article (Mini-Review)

Biomarkers of Acromegaly and Growth Hormone Action

, 27(12): 1231 - 1245

Filippo Maffezzoni, Teresa Porcelli, Andrea Delbarba, Letizia Pezzaioli, Carlo Cappelli and Alberto Ferlin*


DOI: 10.2174/0929866527666200420103816


Review Article (Mini-Review)



Review Article

Protein Markers in Osteoporosis

, 27(12): 1253 - 1259

Teresa Porcelli, Letizia Pezzaioli, Andrea Delbarba, Filippo Maffezzoni, Carlo Cappelli and Alberto Ferlin*


DOI: 10.2174/1871530320666200425204634


Protein & Peptide Letters, Volume 28 (2021) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Protein & Peptide Letters, Volume 28 (2021) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



HIV-1 Accessory Proteins: Which one is Potentially Effective in Diagnosis and Vaccine Development?


Alireza Milani, Kazem Baesi, Elnaz Agi, Ghazal Marouf, Maryam Ahmadi and Azam Bolhassani*


DOI: 10.2174/0929866528999201231213610
View Abstract







Evaluation of the In Vivo Acute Toxicity and In Vitro Hemolytic and Immunomodulatory Activities of the Moringa oleifera Flower Trypsin Inhibitor (MoFTI)


Leydianne Leite de Siqueira Patriota, Dayane Kelly Dias do Nascimento Santos, Bárbara Rafaela da Silva Barros, Lethícia Maria de Souza Aguiar, Yasmym Araújo Silva, Angela Caroline Lima Amorim dos Santos, Mariana Gama e Silva, Luana Cassandra Breitenbach Barroso Coelho, Patrícia Maria Guedes Paiva, Emmanuel Viana Pontual, Cristiane Moutinho Lagos de Melo, Rosemairy Luciane Mendes and Thiago Henrique Napoleão*


DOI: 10.2174/0929866527999201113105858
View Abstract View on PubMed


N-Terminally Added Tag Selectively Enhances Heterologous Expression of VacA Cytotoxin Variants from Helicobacter pylori


Aung Khine Linn, Nitchakan Samainukul, Somsri Sakdee, Chonthicha Butnampetch, Hui-Chun Li, Chanan Angsuthanasombat* and Gerd Katzenmeier


DOI: 10.2174/0929866527666201112122831
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions

, 2020; 27(12): 1204 - 1230

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555




Development of Cell Penetrating Peptides for Effective Delivery of Recombinant Factors into Target Cells

, 2020; 27(11): 1092 - 1101

Ubashini Vijakumaran, Fazlina Nordin*, Zariyantey Abdul Hamid, Maha Abdullah and Tye Gee Jun


DOI: 10.2174/0929866527666200525164135



CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy: A Review

, 2020; 27(10): 931 - 944

Fatima Akram*, Ikram ul Haq, Zeeshan Ahmed, Hamza Khan and Muhammad Shrafat Ali


DOI: 10.2174/0929866527666200407112432



Neuropeptide Y Induces Cardiomyocyte Hypertrophy via Attenuating miR-29a-3p in Neonatal Rat Cardiomyocytes

, 2020; 27(9): 878 - 887

Yuxin Xie, Jun Hu, Xincai Zhang, Chunxiao Li, Yuanyi Zuo, Shining Xie, Zhixiang Zhang and Shaohua Zhu*


DOI: 10.2174/0929866527666200416144459



Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials

, 2020; 27(8): 688 - 697

Yu Chen, Kai Tao, Wei Ji, Pandeeswar Makam, Sigal Rencus-Lazar and Ehud Gazit*


DOI: 10.2174/0929866527666200212123542



Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer Patients

, 2020; 27(7): 658 - 673

Ayesha Zafar, Maryum Jabbar, Yasmeen Manzoor, Huma Gulzar, Shahzad Gul Hassan, Muniba Anum Nazir, Ain-ul-Haq, Ghazala Mustafa, Romana Sahar, Aqeel Masood, Ahtesham Iqbal, Mulazim Hussain and Murtaza Hasan*


DOI: 10.2174/0929866527666200110155609



The Renin-Angiotensin System in Huntington’s Disease: Villain or Hero?

, 2020; 27(6): 456 - 462

Thatiane C.G. Machado, Cristina Guatimosim* and Lucas M. Kangussu*


DOI: 10.2174/0929866527666200110154523



Characterization of an Intermediate Filament Protein from the Platyhelminth, Dugesia japonica

, 2020; 27(5): 432 - 446

Akiko Yamamoto, Ken-ichiro Matsunaga, Toyoaki Anai, Hitoshi Kawano, Toshihisa Ueda, Toshihiko Matsumoto and Shoji Ando*


DOI: 10.2174/0929866526666191025102902




Open Access Articles


Expression, Purification and Characterization of Recombinant Human Coagulation Factor XIIIa in Pichia Pastoris

, 2021; 28(1): 55 - 62

Linyan Cheng, Ting Zhang, Yuchang Fei, Hao Shen, Hui Huang, Jin Chen, Bin Xu* and Jian Xu*




Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?

, 2020; 27(12): 1186 - 1191

Giuseppe Grande*, Domenico Milardi, Silvia Baroni, Andrea Urbani and Alfredo Pontecorvi




The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence

, 2020; 27(6): 463 - 475

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*




miR-146a-5p Regulated Cell Proliferation and Apoptosis by Targeting SMAD3 and SMAD4

, 2020; 27(5): 411 - 418

Meiyu Qiu, Tao Li, Binhu Wang, Hongbin Gong and Tao Huang*





NMAAP1 Maintains M1 Phenotype in Macrophages Through Binding to IP3R and Activating Calcium-related Signaling Pathways

, 2019; 26(10): 751 - 757

Qihui Liu, Pei Zhu, Shanshan Liu, Mengyan Tang, Yuanxin Wang, Yuan Tian, Zheng Jin, Dong Li and Dongmei Yan*






Differential S-acylation of Enveloped Viruses

, 2019; 26(8): 588 - 600

Larisa V. Kordyukova*, Marina V. Serebryakova, Vladislav V. Khrustalev and Michael Veit





Little Antimicrobial Peptides with Big Therapeutic Roles

, 2019; 26(8): 564 - 578

Dan Zhang, Yu He, Yang Ye, Yanni Ma, Peng Zhang, Hongxia Zhu, Ningzhi Xu and Shufang Liang*





Dimerization of Antimicrobial Peptides: A Promising Strategy to Enhance Antimicrobial Peptide Activity

, 2019; 26(2): 98 - 107

Esteban N. Lorenzon, Julia P. Piccoli, Norival A. Santos-Filho and Eduardo M. Cilli*






Most Cited Articles

Review Article

Clinical applications of antimicrobial peptides (AMPs): Where do we stand now?

, 2020; 27(2): 120-134.

Mithoor Divyashree, Madhu K. Mani, Dhanasekhar Reddy, Ranjith Kumavath*, Preetam Ghosh, Vasco Azevedo and Debmalya Barh*


DOI: 10.2174/0929866526666190925152957


Review Article (Mini-Review)

Mini review on antimicrobial peptides, sources, mechanism and recent applications

, 2020; 27(1): 4-16.

Jaspreet Kaur Boparai and Pushpender Kumar Sharma*


DOI: 10.2174/0929866526666190822165812



Research Article

Characterizing the binding of angiotensin converting enzyme i inhibitory peptide to human hemoglobin: Influence of electromagnetic fields

, 2020; 27(10): 1007-1021.

Farzaneh Sadeghzadeh, Amir Arsalan Entezari, Kiana Behzadian, Kimia Habibi, Zeinab Amiri-Tehranizadeh*, Ahmad Asoodeh, Mohammad Reza Saberi and Jamshidkhan Chamani*


DOI: 10.2174/1871530320666200425203636


Review Article

The renin-angiotensin system and the cerebrovascular diseases: Experimental and clinical evidence

, 2020; 27(6): 463-475.

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929866527666191218091823


Review Article

Recombinant protein production in microalgae: Emerging trends

, 2020; 27(2): 105-110.

Niaz Ahmad*, Muhammad Aamer Mehmood and Sana Malik


DOI: 10.2174/0929866526666191014124855


Review Article (Mini-Review)

Adipokines: A rainbow of proteins with metabolic and endocrine functions

, 2020; 27(12): 1204-1230.

Sara Parrettini, Massimiliano Cavallo, Francesco Gaggia, Riccardo Calafiore and Giovanni Luca*


DOI: 10.2174/0929866527666200505214555


Systematic Review Article

Renin-angiotensin-aldosterone system and migraine: A systematic review of human studies

, 2020; 27(6): 512-519.

Karina Lúcia Moreira Sassi, Laís Bhering Martins, Aline Silva de Miranda and Antonio Lucio Teixeira*


DOI: 10.2174/0929866527666200129160136


Review Article

Renin-angiotensin system and Alzheimer’s disease pathophysiology: From the potential interactions to therapeutic perspectives

, 2020; 27(6): 484-511.

Victor Teatini Ribeiro *, Leonardo Cruz de Souza and Ana Cristina Simões e Silva


DOI: 10.2174/0929866527666191230103739


Review Article (Mini-Review)

Exploring the evidence implicating the renin-angiotensin system (RAS) in the physiopathology of mood disorders

, 2020; 27(6): 449-455.

Satyajit Mohite, Marsal Sanches and Antonio L. Teixeira*


DOI: 10.2174/0929866527666191223144000



Research Article

In silico and in vitro investigation of a likely pathway for anti-cancerous effect of thrombocidin-1 as a novel anticancer peptide

, 2020; 27(8): 751-762.

Abbas Tanhaian, Elyas Mohammadi, Roghayyeh Vakili-Ghartavol, Mohammad Reza Saberi, Mehdi Mirzayi* and Mahmoud Reza Jaafari*


DOI: 10.2174/0929866527666200219115129


Research Article

Antimicrobial and antibiofilm activity of Lys-[Trp6]hy-a1 combined with ciprofloxacin against gram-negative bacteria

, 2020; 27(11): 1124-1131.

Victor Alves Carneiro*, Simone Torres de Oliveira, Rondinely Lima Silva, Humberlania de Sousa Duarte, Maria Laína Silva, Maria Nágila Carneiro Matos, Rafaela Mesquita Bastos Cavalcante, Ciro Siqueira Figueira, Esteban Nicolás Lorenzón, Eduardo Maffud Cilli and Rodrigo Maranguape Silva da Cunha


DOI: 10.2174/0929866527666200416145549


Research Article

Separation of the epitopes in a multi-epitope chimera: Helical or flexible linkers

, 2020; 27(7): 604-613.

Mona Kabiri, Mohsen Tafaghodi, Mohammad Reza Saberi, Maliheh Moghadam, Seyed Abdolrahim Rezaee and Mojtaba Sankian*


DOI: 10.2174/0929866526666191112124602


Research Article

Aloperine induces apoptosis by a reactive oxygen species activation mechanism in human ovarian cancer cells

, 2020; 27(9): 860-869.

Mingning Qiu, Jie Liu, Yongxia Su, Jianjun Liu, Chenchen Wu and Baoyu Zhao*


DOI: 10.2174/0929866527666200320094313



Most Accessed Articles

Mechanisms of Lignin-Degrading Enzymes

, 2020; 27(7): 574-581.

Jianlong Xiao, Sitong Zhang* and Guang Chen*


DOI: 10.2174/0929866527666191223141756



Characterization of Three Osmotin-Like Proteins from Plumeria rubra and Prospection for Adiponectin Peptidomimetics

, 2020; 27(7): 593-603.

Cleverson D.T. de Freitas*, Beatriz C. Nishi, Camila T.M. do Nascimento, Maria Z.R. Silva, Eduardo H.S. Bezerra, Bruno A.M. Rocha, Thalles B. Grangeiro, João P.B. de Oliveira, Pedro F. Noronha Souza and Márcio V. Ramos*


DOI: 10.2174/0929866527666200129154357


Separation of the Epitopes in a Multi-Epitope Chimera: Helical or Flexible Linkers

, 2020; 27(7): 604-613.

Mona Kabiri, Mohsen Tafaghodi, Mohammad Reza Saberi, Maliheh Moghadam, Seyed Abdolrahim Rezaee and Mojtaba Sankian*


DOI: 10.2174/0929866526666191112124602



Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer Patients

, 2020; 27(7): 658-673.

Ayesha Zafar, Maryum Jabbar, Yasmeen Manzoor, Huma Gulzar, Shahzad Gul Hassan, Muniba Anum Nazir, Ain-ul-Haq, Ghazala Mustafa, Romana Sahar, Aqeel Masood, Ahtesham Iqbal, Mulazim Hussain and Murtaza Hasan*


DOI: 10.2174/0929866527666200110155609



Purification and Characterization of a Novel Rhamnose/Fucose-Specific Lectin from the Hemolymph of Oak Tasar (Antheraea proylei J.) Silkworm

, 2020; 27(7): 649-657.

Hijam Kiranbala Devi, Sanjenbam Kunjeshwori Devi*, Huidrom Rully, Sorokhaibam Jibankumar Singh, Wayenbam Sobhachandra Singh, Helena Thongam and Laishram Rupachandra Singh


DOI: 10.2174/0929866527666200129155343



Prospecting Potential Inhibitors of Sortase A from Enterococcus faecalis: A Multidrug Resistant Bacteria, through In-silico and In-vitro Approaches

, 2020; 27(7): 582-592.

Satyajeet Das, Vijay Kumar H.S., Sudhir K. Pal, Vijay K. Srivastava, Anupam Jyoti, Sanjit Kumar and Sanket Kaushik*


DOI: 10.2174/0929866527666191227143048




The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence

, 2020; 27(6): 463-475.

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929866527666191218091823


Cross-talk of Signaling Pathways in the Pathogenesis of Allergic Asthma and Cataract

, 2020; 27(9): 810-822.

Yang Zhao, Sumei Liu, Xiangsheng Li, Zhenzhen Xu , Lifang Hao, Zhe Cui, Kewei Bi, Yanfen Zhang* and Zhongcheng Liu*


DOI: 10.2174/0929866527666200207113439




Editor-in-Chief

Prof. Ben M. Dunn
Department of Biochemistry and Molecular Biology
University of Florida
College of Medicine
Gainesville, FL
(USA)
Email: bdunn@ufl.eduBiography
View Full Editorial Board

COPE Compliant

Journal History

Protein & Peptide Letters was introduced in 2001 with the assistance of Dr. Ben M. Dunn, who is the current Editor-in-Chief serving since 2001.
Scopus CiteScore Metrics: 1.14

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