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Current Drug Targets

Volume 20, 16 Issues, 2019
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 20

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Number 8



Editorial   Open Access



Review Article



Review Article   Open Access



Review Article

Photopolymerizable Resins for 3D-Printing Solid-Cured Tissue Engineered Implants

, 20(8): 823 - 838

Antonio J. Guerra, Hernan Lara-Padilla, Matthew L. Becker, Ciro A. Rodriguez and David Dean*


DOI: 10.2174/1389450120666190114122815


Review Article



General Review Article



General Review Article



General Review Article



Current Drug Targets, Volume 20 (2019) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print





Are Surgical Rates Decreasing in the Biological Era In IBD?


Francesca Di Candido*, Gionata Fiorino, Marco Spadaccini, Silvio Danese and Antonino Spinelli


View Abstract





Silicon Quantum Dots: Promising Theranostic Probes for the Future


Vishnu Sankar Sivasankarapillai, Jobin Jose, Muhammad Salman Shanavas, Akash Marathakam, Md. Sahab Uddin and Bijo Mathew*


View Abstract View on PubMed



Abstracts Ahead of Print

Medical-surgical combined approach in perianal fistulizing Crohn's disease (CD): doing it together


Kapil Sahnan*, Samuel O Adegbola, Ana Fareleira, Ailsa Hart and Janindra Warusavitarne


View Abstract


Published Contents

Editor's Choice


Targeting Water in the Brain: Role of Aquaporin-4 in Ischemic Brain Edema

, 2019; 20(7): 748 - 755

Muyassar Mamtilahun, Guanghui Tang, Zhijun Zhang, Yongting Wang, Yaohui Tang* and Guo-Yuan Yang*


DOI: 10.2174/1389450120666190214115309



Estrogen Receptor Alpha and its Ubiquitination in Breast Cancer Cells

, 2019; 20(6): 690 - 704

Angeles C. Tecalco-Cruz*, Josué O. Ramírez-Jarquín and Eduardo Cruz-Ramos


DOI: 10.2174/1389450119666181015114041



Understanding Membrane Protein Drug Targets in Computational Perspective

, 2019; 20(5): 551 - 564

Jianting Gong, Yongbing Chen, Feng Pu, Pingping Sun, Fei He, Li Zhang, Yanwen Li*, Zhiqiang Ma* and Han Wang*


DOI: 10.2174/1389450120666181204164721



Influence of Ultrafine Particles Exposure on Asthma Exacerbation in Children: A Meta-Analysis

, 2019; 20(4): 412 - 420

Qinyuan Li, Qian Yi, Lin Tang, Siying Luo, Yuan Tang, Guangli Zhang and Zhengxiu Luo*


DOI: 10.2174/1389450119666180829114252



A Review on Quantum Dots: Synthesis to In- silico Analysis as Next Generation Antibacterial Agents

, 2019; 20(3): 255 - 262

Sounik Manna, Munmun Ghosh, Ranadhir Chakraborty, Sudipto Ghosh and Santi M. Mandal*


DOI: 10.2174/1389450119666180731142423






Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

, 2018; 19(15): 1731 - 1737

Marcin Włodarczyk*, Jakub Włodarczyk, Paweł Siwiński, Aleksandra Sobolewska-Włodarczyk and Jakub Fichna


DOI: 10.2174/1389450119666180803122744



Open Access Articles


Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga




Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy

, 2016; 17(8): 954 - 970

Mark Walsh, Stephanie Fritz, Daniel Hake, Michael Son, Sarah Greve, Manar Jbara, Swetha Chitta, Braxton Fritz, Adam Miller, Mary K Bader, Jonathon McCollester, Sophia Binz, Alyson Liew-Spilger, Scott Thomas, Anton Crepinsek, Faisal Shariff, Victoria Ploplis and Francis J. Castellino




Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance

, 2016; 17(2): 164 - 177

Gabriela Nestal de Moraes, Laura Bella, Stefania Zona, Matthew J. Burton and Eric W.-F. Lam




Biologics for Extraintestinal Manifestations of IBD

, 2014; 15(11): 1064 - 1073

Stephan R. Vavricka, Michael Scharl, Martin Gubler and Gerhard Rogler







Most Cited Articles

Review Article

Cytochrome P450 structure, function and clinical significance: A review

, 2018; 19(1): 38-54.

Palrasu Manikandan and Siddavaram Nagini*


DOI: 10.2174/1389450118666170125144557



Review Article

Insights into the targeting potential of thymoquinone for therapeutic intervention against triple-negative breast cancer

, 2018; 19(1): 70-80.

Md Abul Barkat, Harshita, Javed Ahmad, Mohammad Ahmed Khan*, Sarwar Beg* and Farhan Jalees Ahmad*


DOI: 10.2174/1389450118666170612095959


Review Article

Stimuli-responsive smart liposomes in cancer targeting

, 1 March 2018; 19(3): 259-270.

Ankit Jain and Sanjay K. Jain*


DOI: 10.2174/1389450117666160208144143



Review Article

Complexation of bioelements and toxic metals by polyphenolic compounds – Implications for health

, 2018; 19(14): 1612-1638.

Sylwia Borowska*, Malgorzata Michalina Brzoska* and Michal Tomczyk


DOI: 10.2174/1389450119666180403101555


Review Article

Recent advances in protein tyrosine phosphatase 1b targeted drug discovery for Type II diabetes and obesity

, 1 April 2018; 19(5): 551-575.

Neelesh Maheshwari, Chandrabose Karthikeyan, Piyush Trivedi and N.S. Hari Narayana Moorthy*


DOI: 10.2174/1389450118666170222143739


Review Article

Blood eosinophils as biomarkers to drive treatment choices in asthma and COPD

, 2018; 19(16): 1882-1896.

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*


DOI: 10.2174/1389450119666180212120012


Review Article

Metformin, a new era for an old drug in the treatment of immune mediated disease?

, 2018; 19(8): 945-959.

Mark Schuiveling, Nadia Vazirpanah, Timothy R.D.J. Radstake, Maili Zimmermann* and Jasper C.A. Broen*


DOI: 10.2174/1389450118666170613081730


Review Article

GRP78 influences chemoresistance and prognosis in cancer

, 2018; 19(6): 701-708.

Jenifer B. Gifford and Reginald Hill*


DOI: 10.2174/1389450118666170615100918


Review Article

Antitumor activity of polysaccharides: An overview

, 2018; 19(1): 89-96.

Ling Chen and Gangliang Huang*


DOI: 10.2174/1389450118666170704143018



Review Article

Current status and perspectives on pharmacologic therapy for abdominal aortic aneurysm

, 2018; 19(11): 1265-1275.

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano


DOI: 10.2174/1389450119666171227223331


Review Article

Epigenetic biomarkers for risk assessment of particulate matter associated lung cancer

, 2018; 19(10): 1127-1147.

Arpit Bhargava, Neha Bunkar, Aniket Aglawe, Kailash Chand Pandey, Rajnarayan Tiwari, Koel Chaudhury, Irina Yu Goryacheva and Pradyumna Kumar Mishra*


DOI: 10.2174/1389450118666170911114342


Review Article

The use of methylphenidate for physical and psychological symptoms in cancer patients: A review

, 2018; 19(8): 877-887.

Beatrice Ng Andrew, Ng Chong Guan* and Nik Ruzyanei Nik Jaafar


DOI: 10.2174/1389450118666170317162603



Most Accessed Articles







Melatonin as Potential Targets for Delaying Ovarian Aging

, 2019; 20(1): 16-28.

Yanzhou Yang*, Hoi-Hung Cheung, Cheng Zhang, Ji Wu and Wai-Yee Chan


DOI: 10.2174/1389450119666180828144843


Potential Therapeutic Agents Against Par-4 Target for Cancer Treatment: Where Are We Going?

, 2019; 20(6): 635-654.

Renata Virgínia Cavalcanti Santos, Wanessa Layssa Batista de Sena, Flaviana Alves dos Santos, Antônio Felix da Silva Filho, Marina Galdino da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Barreto de Melo Rego and Michelly Cristiny Pereira*


DOI: 10.2174/1389450120666181126122440


Coping With Oxidative Stress. The Yeast Model

, 2015; 16(1): 2-12.

Maria Angeles de la Torre-Ruiz, Nuria Pujol and Venkatraghavan Sundaran


DOI: 10.2174/1389450115666141020160105




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