Articles Ahead of Print


Interindividual Variability in Drug Metabolizing Enzymes


Donna A. Volpe*






Role of Osmolytes and their Transporter Systems in Pathogen Survival and Pathogenicity


Safikur Rahman, Ayyagari Archana, Mudsser Azam and Rinki Minakshi*


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Amino Acid Metabolism in Dairy Cows and their Regulation in Milk Synthesis


Feiran Wang, Haitao Shi, Shuxiang Wang, Yajing Wang, Zhijun Cao and Shengli Li*


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Optimization of Drugs Pharmacotherapy During Pregnancy Using Physiologically Based Pharmacokinetic Models - An Update


Mo’tasem M. Alsmadi* and Nasir Idkaidek


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Thiazide Therapy in Chronic Kidney Disease: Renal and Extra Renal Targets


Negiin Pourafshar , Saeed Alshahrani , Ashkan Karimi and Manoocher Soleimani*


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Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective


Joana Goncalves , Joana Bicker , Gilberto Alves , Ana Fortuna* and Amilcar Falcao


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The Pharmacogenomics of Asthma Beyond its Endotypes


Shuhui Meng , Shuyu Chen and Ailin Tao*


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Recent Advances in Gold Nanoformulations for Cancer Therapy


Maxim Shevtsov*, Yang Zhou, William Khachatryan, Gabriele Multhoff and Huile Gao*


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Genetic Polymorphism on the Pharmacokinetics and Pharmacodynamics of Plateletderived Growth Factor Receptor (PDGFR) Kinase Inhibitors


Yi Qian, Lei Yu, Xue-Hui Zhang, Qing-Yun Yuan-Zi, Ping Zhao, Lu-ning Sun and Yong-Qing Wang*


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Current Designs of Polymer Blends in Solid Dispersions for Improving Drug Bioavailability


Phuong Ha-Lien Tran, Wei Duan, Beom-Jin Lee and Thao TD Tran*


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The Role of E-cadherin in Helicobacter pylori-Related Gastric Diseases


Yunzhan Zhang, Danyan Li, Yunkai Dai, Ruliu Li, Yong Gao and Ling Hu*


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Hypoxia Plays a Key Role in the Pharmacokinetic Changes of Drugs at High Altitude


Xuejiao Zhou, Yongqiong Nian , Yijie Qiao, Meng Yang, Yuanyao Xin and Xiangyang Li*


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The Therapeutic Role of Xenobiotic Nuclear Receptors Against Metabolic Syndrome


Shuqi Pu, Xiaojie Wu, Xiaoying Yang, Yunzhan Zhang, Yunkai Dai, Yueling Zhang, Xiaoting Wu, Yan Liu, Xiaona Cui, Haiyong Jin, Jianhong Cao, Ruliu Li, Jiazhong Cai, Qizhi Cao, Ling Hu and Yong Gao*


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Impact of Drug Metabolism/Pharmacokinetics and their Relevance Upon Taxusbased Drug Development


Da-Cheng Hao*, Guang-Bo Ge, Ping Wang and Ling Yang


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Polysaccharide Nanoparticles for Targeted Cancer Therapies


Peipei Peng , Ke Yang, Gangsheng Tong and Liang Ma*


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The Application of Natural Products in Cancer Therapy by Targeting Apoptosis Pathways


Yan Wang, Jian Zhong, Jiaojiao Bai, Rongsheng Tonga, Feifei An, Pengcheng Jiao, Lin He, Daiwen Zeng, Enwu Long, Junfeng Yan, Jiying Yu and Lulu Cai*


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Advances in Long-Circulating Drug Delivery Strategy


Xinyu Zhang, Shaohan Zhang, Yang Kang, Keqing Huang, Zhipeng Gu* and Jun Wu


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Anti-cancer Effects of Metformin: Recent Evidences for its Role in Prevention and Treatment of Cancer


Masoumeh Kheirandish, Hamidreza Mahboobi*, Maryam Yazdanparast, Warda Kamal and Mohammad A. Kamal


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A Review on Clinical Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Natalizumab: A Humanized Anti-A4 Integrin Monoclonal Antibody


Li Hao, Shi Fang-Hong*, Huang Shi-Ying, Zhang Shun-Guo and Chen Min-Ling


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Role of Angiogenenic Growth Factors in Psoriasis: A Review


Tahseena Akhtar, Willayat Yousuf Wani, Mohammad A. Kamal and Rajinder Kaur*


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Preclinical Hepatoprotective Effect of Herbalism Against Ethanol Induced Hepatotoxicity: A Review


Monika Singh, Talib Hussain*, Hina Firdous, Syed Mohd. Danish Rizvi, Afrasim Moin and Mohammad Amjad Kamal


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Formulations, Pharmacodynamic and Clinical Studies of Nanoparticles for Lung Cancer Therapy - An Overview


Dandan Zheng, Jinglong Wang, Shengrong Guo, Zhongxi Zhao and Feihu Wang*


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A Synopsis on the Role of Human Papilloma Virus Infection in Cervical Cancer


Mohd Saeed, Fawaz D Alshammari, Md. Jahoor Alam, Khan Mohd Sarim, Khurshid Ahmad, Talib Hussain, Mahvish Khan, Muhammad Amjad Kamal and Ghulam Md. Ashraf*


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Association of Metronidazole with Cancer: A Potential Risk Factor or Inconsistent Deductions?


Muhammad Adil, Waheed Iqbal, Fazal Adnan, Shabnam Wazir, Imran Khan, Mohammad Umar Khayam, Mohammad Amjad Kamal, Shafiq Ahmad, Jawad Ahmad and Ishaq N. Khan*


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Sodium Oxybate Treatment in Pediatric Type 1 Narcolepsy


Monica Moresco, Fabio Pizza, Elena Antelmi and Giuseppe Plazzi*


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Kisspeptin and its Effect on Mammalian Spermatogensis


Tao Feng*, Jiahua Bai, Xiaoling Xu and Yan Liu


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How to Control Asthma with Personalized Management: Where Do We Stand Now?


Meng Wang, Yuan Yao, Shanqun Jiang, Fang Tao, Rui Tang and Jinlu Sun*


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Effects of GHB On Psychomotor and Driving Performance


Carmela Centola, Arianna Giorgetti, Simona Zaami and Raffaele Giorgetti*


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Influence of Genetic Polymorphisms on Mycophenolic Acid Pharmacokinetics and Patient Outcomes in Renal Transplantation


Miao Guo*, Zi-Jie Wang, Hai-Wei Yang, Ling Meng, Ruo-Yun Tan, Min Gu and Ji-Fu Wei


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Long Circulating Polymeric Nanoparticles for Gene/Drug Delivery


Jiaming Hu, Yan Sheng*, Junfeng Shi, Bohao Yu, Zhiqiang Yu and Guochao Liao*


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Sodium Oxybate Therapy for the Treatment of Alcohol Withdrawal Syndrome and the Maintenance of Alcohol Abstinence


Carmen Mannucci, Simona Pichini, Elvira Ventura Spagnolo, Fabrizio Calapai, Sebastiano Gangemi, Michele Navarra and Gioacchino Calapai*


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The Effects of Genetic Polymorphism on Treatment Response of Recombinant Human Growth Hormone


Shi Chen, Hanxiao You*, Hui Pan, Huijuan Zhu, Hongbo Yang, Fengying Gong, Linjie Wang, Yu Jiang and Chengsheng Yan


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Deaths in the Lesbian, Gay, Bisexual and Transgender United Kingdom Communities Associated with GHB And Precursors


John M. Corkery*, Barbara Loi, Hugh Claridge, Christine Goodair and Fabrizio Schifano


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