Bentham Science Logo
Journal Cover

Track Your Manuscript:


Current Topics in Medicinal Chemistry

Volume 21, 32 Issues, 2021
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

Aims & Scope

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

Current Topics in Medicinal Chemistry

,

Volume 21

-

Number 25



Editorial   Open Access



Review Article



Research Article



Review Article



General Review Article

Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR)

, 21(25): 2292 - 2349

Ajay Manaithiya, Ozair Alam*, Vrinda Sharma, Mohd. Javed Naim, Shruti Mittal, Faizul Azam, Asif Husain, Aadil Ahmad Sheikh, Mohd. Imran and Imran A. Khan


DOI: 10.2174/1568026621666210916171015


Current Topics in Medicinal Chemistry, Volume 21 (2021) - Number 28


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 21 (2021) - Number 27


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 21 (2021) - Number 26


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print






Bergenin - A Biologically Active Scaffold: Nanotechnological Perspectives


Reecha Madaan, Rajeev K. Singla*, Suresh Kumar, Ankit Kumar Dubey, Dinesh Kumar, Pooja Sharma, Rajni Bala, Shailja Singla and Bairong Shen


DOI: 10.2174/1568026621666211015092654
View Abstract View on PubMed



Drug Repurposing Meets DNA Independent Pathways: Targeting Alternative Substrates for Anticancer Therapy


Tiziano Marzo, Sabrina Taliani, Silvia Salerno, Federico Da Settimo, Elisabetta Barresi* and Diego La Mendola


DOI: 10.2174/1568026621666211004093023
View on PubMed




Abstracts Ahead of Print


Immunomodulatory effects of Allium Sativum L. and its constituents against viral infections and metabolic diseases


María del Rayo Camacho-Corona*, Alberto Camacho-Morales, Fernando Góngora-Rivera, Erandi Escamilla-García, Juan Luis Morales-Landa, Mariana Andrade-Medina, Aldo Fernando Herrera-Rodulfo, Martín García-Juárez, Patricio García-Espinosa, Tommaso Stefani, Patricia González-Barranco and Mauricio Carrillo-Tripp*


DOI: 10.2174/1568026621666211122163156
View Abstract







Ternary System of Bacogenins with Fulvic Acid and Hydrogenated Soy Lecithin: Preparation, Characterization and, In-Vivo Studies


Kattamanchi Gnananath, Kalakonda Sri Nataraj*, Battu Ganga Rao, Kolli Prabhanjan Kumar, Kommavari Chandrasekhar, Pooja Jain and Mohd. Aamir Mirza*


DOI: 10.2174/1568026621666211111155425
View Abstract



Effects of flavonoids in experimental models of arterial hypertension


Noemi M. Atucha, Paola Romecín, Felix Vargas and Joaquin García-Estañ*


DOI: 10.2174/1568026621666211105100800
View Abstract


Published Contents

Editor's Choice


Parallelization of Molecular Docking: A Review

, 2018; 18(12): 1015 - 1028

Dong Dong, Zhijian Xu, Wu Zhong and Shaoliang Peng*


DOI: 10.2174/1568026618666180821145215




A Review on Plant Antimicrobials of Past Decade

, 2018; 18(10): 812 - 833

Preet Amol Singh, Sapna D. Desai and Jasbir Singh*


DOI: 10.2174/1568026618666180516123229




Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

, 2018; 18(8): 714 - 746

Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*


DOI: 10.2174/1568026618666180604082610






Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

, 2018; 18(4): 256 - 274

Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao


DOI: 10.2174/1568026618666180410151518



Open Access Articles

An Overview of Ovarian Cancer: Molecular Processes Involved and Development of Target-based Chemotherapeutics

, 2021; 21(4): 329 - 346

Basheerulla Shaik, Tabassum Zafar, Krishnan Balasubramanian and Satya P. Gupta*





Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers - A Review

, 2021; 21(1): 28 - 47

Simon N. Mbugua, Lydia W. Njenga, Ruth A. Odhiambo, Shem O. Wandiga and Martin O. Onani*




Peptide Receptor Radionuclide Therapy: Looking Back, Looking Forward

, 2020; 20(32): 2959 - 2969

Danny Feijtel, Marion de Jong and Julie Nonnekens*




Learning the Edit Costs of Graph Edit Distance Applied to Ligand-Based Virtual Screening

, 2020; 20(18): 1582 - 1592

Carlos Garcia-Hernandez, Alberto Fernández* and Francesc Serratosa




Telomere-related Markers for Cancer

, 2020; 20(6): 410 - 432

Xiaotian Yuan*, Mingkai Dai and Dawei Xu*






Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

, 2019; 19(18): 1621 - 1649

Kenji Maeda*, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura and Hiroaki Takeuchi*




Targeting the PAC1 Receptor for Neurological and Metabolic Disorders

, 2019; 19(16): 1399 - 1417

Chenyi Liao, Mathilde P. de Molliens, Severin T. Schneebeli, Matthias Brewer, Gaojie Song, David Chatenet, Karen M. Braas, Victor May* and Jianing Li*




Ensemble-Based Modeling of Chemical Compounds with Antimalarial Activity

, 2019; 19(11): 957 - 969

Ana Yisel Caballero-Alfonso, Maykel Cruz-Monteagudo, Eduardo Tejera, Emilio Benfenati, Fernanda Borges, M. Natália D.S. Cordeiro, Vinicio Armijos-Jaramillo and Yunierkis Perez-Castillo*





Treatment of Toxoplasmosis and Neosporosis in Farm Ruminants: State of Knowledge and Future Trends

, 2018; 18(15): 1304 - 1323

Roberto Sánchez-Sánchez, Patricia Vázquez, Ignacio Ferre and Luis Miguel Ortega-Mora*




Mechanical Properties of Composite Hydrogels for Tissue Engineering

, 2018; 18(14): 1214 - 1223

Ramon Rial, J.F. Armando Soltero, Pedro V. Verdes, Zhen Liu and Juan M. Ruso*






Most Cited Articles

Review Article

Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases

, 2019; 19(19): 1694-1711.

Viktoriya Ivasiv, Claudia Albertini, Ana E. Gonçalves, Michele Rossi and Maria L. Bolognesi*


DOI: 10.2174/1568026619666190619115735





Review Article

Biological signatures of alzheimer’s disease

, 2020; 20(9): 770-781.

Poornima Sharma, Anjali Sharma, Faizana Fayaz, Sharad Wakode* and Faheem H. Pottoo


DOI: 10.2174/1568026620666200228095553


Review Article

Biological activities of artemisinin derivatives beyond malaria

, 2019; 19(3): 205-222.

Xiaoyan Liu, Jianguo Cao, Guozheng Huang*, Qingjie Zhao* and Jingshan Shen


DOI: 10.2174/1568026619666190122144217


Review Article

Discovery and development of anti-HIV therapeutic agents: Progress towards improved HIV medication

, 2019; 19(18): 1621-1649.

Kenji Maeda*, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura and Hiroaki Takeuchi*


DOI: 10.2174/1568026619666190712204603


Review Article

STAT3: A potential drug target for tumor and inflammation

, 2019; 19(15): 1305-1317.

Yang Sheng Hu, Xu Han and Xin Hua Liu*


DOI: 10.2174/1568026619666190620145052


Review Article

Virtual screening techniques in drug discovery: Review and recent applications

, 2019; 19(19): 1751-1767.

Sheisi F.L. da Silva Rocha, Carolina G. Olanda, Harold H. Fokoue and Carlos M.R. Sant'Anna*


DOI: 10.2174/1568026619666190816101948




Review Article

Mycobacterial tuberculosis Enzyme Targets and their Inhibitors

, 2019; 19(5): 337-355.

Anil Kumar Saxena* and Anamika Singh


DOI: 10.2174/1568026619666190219105722


Review Article

Zinc-depend ent deacetylase (HDAC) inhibitors with different zinc binding groups

, 2019; 19(3): 223-241.

Yan Li, Fang Wang, Xiaoxue Chen, Jie Wang, Yonglong Zhao, Yongjun Li and Bin He*


DOI: 10.2174/1568026619666190122144949



Review Article

PTP1b inhibition, a promising approach for the treatment of diabetes type II

, 2019; 19(4): 246-263.

Phaedra Eleftheriou*, Athina Geronikaki and Anthi Petrou


DOI: 10.2174/1568026619666190201152153



Most Accessed Articles


Thiazolidinedione: A Privileged Scaffold for the Development of Anticancer Agents

, 2021; 21(28): 2529-2545.

Juan Sun, Yue-Hu Chen, Han-Yu Liu, Emmerson Hondo, Yang Zhou* and Yuan-Feng Wu*


DOI: 10.2174/1568026621666210521143550





Sterol 14α-Demethylase from Trypanosomatidae Parasites as a Promising Target for Designing New Antiparasitic Agents

, 2021; 21(21): 1900-1921.

Paulo Fernando da Silva Santos-Júnior, Martine Schmitt, João Xavier de Araújo-Júnior and Edeildo Ferreira da Silva-Júnior*


DOI: 10.2174/1568026621666210303144448





Transition Metal-mediated Uncaging Chemistry in Prodrug Design

, 2021; 21(24): 2205-2212.

Hai Yang Shu, Ren De Zhu, Jing Wu, Xin Hua Liu and Jing Bo Shi*


DOI: 10.2174/1568026621666210624113313









Editor-in-Chief

graphic
Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)
Biography
View Full Editorial Board

COPE Compliant

Cope Logo

Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who served as the editor-in-chief from 2001 to 2020. Currently, Dr. Jia Zhou is the Editor-in-Chief of the journal.

Related Journals

Related eBooks

eBooks Catalog