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"Combinatorial Chemistry & High Throughput Screening is a pivotal journal in the field of drug discovery."
Norman R. Farnsworth
University of Illinois at Chicago, USA
"Combinatorial Chemistry & High Throughput Screening is a pivotal journal in the field of drug discovery."
Norman R. Farnsworth
University of Illinois at Chicago, USA
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The Application of High-Throughput Technologies in Precision Diagnosis and Personalized TherapyGuest Editor(s): Tao Huang Download Description |
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Novel Bioinformatics and Systems Biology approaches and techniques in Pharmaceutical and Biochemical SciencesCombinatorial Chemistry & High Throughput Screening, Volume 21, Number 6 Guest Editor(s): Yudong Cai |
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I would like to greatly appreciate Bentham Science Publishers. They publish many good journals successfully. Bentham Science Publishers made our work easy and pleasant. They gave detailed information whenever required. It was a pleasure for me to work with Bentham Science Publishers. I would like to thank them for everything. Begum Evranos-Aksoz (Medicines and Medical Devices Agency, Analyses and Control Laboratories, Sıhhıye 06100, Ankara, Turkey) |
Combinatorial Chemistry & High Throughput Screening
,Volume 21
-Number 8
Biography Open Access
Meet Our Editorial Board Member
Research Article
A Novel Systemic Indicator of Periodontal Tissue Damage: Ischemia Modified Albumin
, 21(8): 544 - 549Mahmure A. Tayman*, Canan Önder, Şivge Kurgan, Muhittin A. Serdar and Meral Günhan
DOI: 10.2174/1386207321666181018165255
A Novel Systemic Indicator of Periodontal Tissue Damage: Ischemia Modified Albumin
Research Article
Development of an Information System of Structures and Force Field Parameters of Chemical Compounds from Sri Lankan Flora
, 21(8): 550 - 556Samith Rathnayake and Samantha Weerasinghe*
DOI: 10.2174/1386207321666181010113533
Development of an Information System of Structures and Force Field Parameters of Chemical Compounds from Sri Lankan Flora
Research Article
Predicting Inhibitors for Multidrug Resistance Associated Protein-2 Transporter by Machine Learning Approach
, 21(8): 557 - 566Sahil Kharangarh, Hardeep Sandhu , Sujit Tangadpalliwar and Prabha Garg*
DOI: 10.2174/1386207321666181024104822
Predicting Inhibitors for Multidrug Resistance Associated Protein-2 Transporter by Machine Learning Approach
Research Article
Inexpensive Weight-Reducing Aid (L-Carnitine) as An Efficient Catalyst for Synthesis of Benzimidazoles
, 21(8): 567 - 570Min Zhang, Guoling Huang, Xuefang Zhang, Zhenyuan Lin, Yibiao Li, Bin Li and Lu Chen*
DOI: 10.2174/1386207321666181018163940
Inexpensive Weight-Reducing Aid (L-Carnitine) as An Efficient Catalyst for Synthesis of Benzimidazoles
Research Article
Neuroprotective Effects of Extracts from the Radix Curcuma aromatica on H2O2-induced Damage in PC12 Cells
, 21(8): 571 - 582Juxiang Liu, Lianli Zhang, Dan Liu, Baocai Li and Mi Zhang *
DOI: 10.2174/1386207321666181005121457
Neuroprotective Effects of Extracts from the Radix Curcuma aromatica on H2O2-induced Damage in PC12 Cells
Research Article
Synthesis of Functionalized Magnetite Titanium Dioxide Nanocomposite for Removal of Acid Fuchsine Dye
, 21(8): 583 - 593Sara Rahnama, Shahab Shariati* and Faten Divsar
DOI: 10.2174/1386207321666181019111211
Synthesis of Functionalized Magnetite Titanium Dioxide Nanocomposite for Removal of Acid Fuchsine Dye
Research Article
TiO2 NPs-Coated Carbone Nanotubes as a Green and Efficient Catalyst for the Synthesis of [1]Benzopyrano[b][1]benzopyranones and Xanthenols in Water
, 21(8): 594 - 601Shahrzad Abdolmohammadi*
DOI: 10.2174/1386207321666181018164739
TiO2 NPs-Coated Carbone Nanotubes as a Green and Efficient Catalyst for the Synthesis of [1]Benzopyrano[b][1]benzopyranones and Xanthenols in Water
Articles Ahead of Print
There are currently no Articles Ahead of Print available for this journal.
Abstracts Ahead of Print
A network integration method for deciphering the types of metabolic pathway of chemicals with heterogeneous information
Zi-Han Guo, Lei Chen* and Xian Zhao
View Abstract
Editor's Choice
Synthesis of Novel α-amidino Carboxylic Acids and their Use as H-Bond Catalysts in Strecker Reaction
, 2018; 21(8): 609 - 614Zahra Zaghari and Javad Azizian*
DOI: 10.2174/1386207321666181114110039
Application of QSAR Analysis and Different Quantum Chemical Calculation Methods in Activity Evaluation of Selected Fluoroquinolones
, 2018; 21(7): 468 - 475Piotr Kawczak*, Leszek Bober and Tomasz Bączek
DOI: 10.2174/1386207321666180827105856
A Six-Gene Signature Predicts Clinical Outcome of Gastric Adenocarcinoma
, 2018; 21(6): 444 - 452YaQi Li, Qi Yu, Rui Zhu, Yi Wang, Jiarui Li, Qiang Wang, Wenna Guo, Shen Fu* and Liucun Zhu*
DOI: 10.2174/1871524918666180531085713
Assessing and Grouping Chemicals Applying Partial Ordering Alkyl Anilines as an Illustrative Example
, 2018; 21(5): 349 - 357Lars Carlsen* and Rainer Bruggemann
DOI: 10.2174/1386207321666180604103942
Phytochemical Screening, Antiproliferative and Antioxidant Properties of Various Extracts from Endemic Origanum acutidens
, 2018; 21(4): 281 - 291Feyza Oke-Altuntas, Mehmet Ali Demirci, Ibrahim Demirtas*, Ayse Sahin Yaglioglu and Lutfi Behcet
DOI: 10.2174/1386207321666180416154404
Extraction, Identification and Biological Activities of Saponins in Sea Cucumber Pearsonothuria graeffei
, 2018; 21(3): 222 - 231Rafat Afifi Khattab, Mohamed Elbandy, Andrew Lawrence, Tim Paget, Jung Rae-Rho, Yaser S. Binnaser and Imran Ali*
DOI: 10.2174/1386207321666180212165448
Chemometric Analysis for the Classification of some Groups of Drugs with Divergent Pharmacological Activity on the Basis of some Chromatographic and Molecular Modeling Parameters
, 2018; 21(2): 125 - 137Jolanta Stasiak, Marcin Koba*, Marcin Gackowski and Tomasz Baczek
DOI: 10.2174/1386207321666180129102149
A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells
, 2018; 21(1): 50 - 56F. Ricci*, L. Carrassa, M. S. Christodoulou, D. Passarella, B. Michel, R. Benhida, N. Martinet, A. Hunyadi, E. Ioannou, V. Roussis, L. Musso, S. Dallavalle, R. Silvestri, N. Westwood, M. Mori, C. Ingallina, B. Botta, E. Kavetsou, A. Detsi, Z. Majer, F. Hudecz, S. Bosze, B. Kaminska, T.V. Hansen, P. Bertrand, C. M. Athanassopoulos and G. Damia*
DOI: 10.2174/1386207321666180124093406
A Review of Computational Drug Repositioning Approaches
, 2017; 20(10): 831 - 838Guohua Huang*, Jincheng Li, Peng Wang and Weibiao Li
DOI: 10.2174/1386207321666171221112835
High Throughput Screening Assay to Identify Modulators of IL-17 Expression
, 2017; 20(9): 804 - 819Mohamed Boudjelal*, Ana Maria Ruiz-Avendano, Gonzalo Colmenarejo, Sergio A. Senar-Sancho, Ashley Barnes and Stephen A. Harrison*
DOI: 10.2174/1386207320666170602091308
Open Access Articles
Protein Sequence Comparison and DNA-binding Protein Identification with Generalized PseAAC and Graphical Representation
, 2018; 21(2): 100 - 110Chun Li*, Jialing Zhao, Changzhong Wang and Yuhua Yao
High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review
, 2016; 19(8): 605 - 615Carlina Peña-García, Mónica Martínez-Martínez, Dolores Reyes-Duarte* and Manuel Ferrer*
An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever
, 2016; 19(7): 516 - 536Chelsea N. Powers and William N. Setzer*
Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library
, 2016; 19(4): 262 - 274Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh G. Santos, Marc A. Giulianotti and Robert J. Deschenes*
Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
, 2015; 18(1): 3 - 17Arjan J. van Adrichem, Annika Fagerholm, Laura Turunen, Anna Lehto, Jani Saarela, Ari Koskinen, Gretchen A. Repasky and Krister Wennerberg*
Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening
, 2014; 17(1): 80 - 88Benjamin Rappaz, Billy Breton, Etienne Shaffer and Gerardo Turcatti*
Chemical Informatics and the Drug Discovery Knowledge Pyramid
, 2013; 16(10): 764 - 776Gerald H. Lushington*, Yinghua Dong and Bhargav Theertham
A Generalized Model and High Throughput Data Analysis System for Functional Modulation of Receptor-Agonist Systems Suitable for use in Drug Discovery
, 2013; 16(3): 199 - 209Aaron C. Pawlyk*, R. Kyle Palmer, Dennis Sprous and Chip Allee
A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization
, 2012; 15(9): 686 - 704Bhavneet Bhinder and Hakim Djaballah*
Application of NMR Metabolomics to Search for Human Disease Biomarkers
, 2012; 15(8): 595 - 610Teklab Gebregiworgis and Robert Powers*
Alternative Medicine Safety: Agaricus blazei and Propolis
, 2011; 14(7): 616 - 621Kenji Sorimachi* and Takaaki Nakamoto
The Design and Application of Target-Focused Compound Libraries
, 2011; 14(6): 521 - 531C. John Harris, Richard D. Hill, David W. Sheppard*, Martin J. Slater and Pieter F.W. Stouten
Two Panels of Steroid Receptor Luciferase Reporter Cell Lines for Compound Profiling
, 2011; 14(4): 248 - 266David Sedlak, Aileen Paguio and Petr Bartunek*
Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance
, 2010; 13(2): 188 - 206James M. McKim Jr.*
Generating ‘Omic Knowledge’: The Role of Informatics in High Content Screening
, 2009; 12(9): 917 - 925Mark A. Collins*
Most Cited Articles
Predicting the types of metabolic pathway of compounds using molecular fragments and sequential minimal optimization
, 2016; 19(2): 136-143.Lei Chen, Chen Chu and Kaiyan Feng
DOI: 10.2174/1386207319666151110122453
A novel machine learning method for cytokine-receptor interaction prediction
, 2016; 19(2): 144-152.Leyi Wei, Quan Zou, Minghong Liao, Huijuan Lu and Yuming Zhao
DOI: 10.2174/1386207319666151110122621
SAnDReS a Computational Tool for Statistical Analysis of Docking Results and Development of Scoring Functions
, 2016; 19(10): 801-812.Mariana Morrone Xavier, Gabriela Sehnem Heck, Mauricio Boff de Avila, Nayara Maria Bernhardt Levin, Val Oliveira Pintro, Nathalia Lemes Carvalho and Walter Filgueira de Azevedo
DOI: 10.2174/1386207319666160927111347
A Theoretical Study on Stepwise- and Concertedness of the Mechanism of 1,3-Dipolar Cycloaddition Reaction Between Tetra Amino Ethylene and Trifluoro Methyl Azide
, 2016; 19(2): 170-175.Seyyed Amir Siadati
DOI: 10.2174/1386207319666151216145408
Molecular Modeling and Virtual Screening Approach to Discover Potential Antileishmanial Inhibitors Against Ornithine Decarboxylase
, 2016; 19(10): 813-823.Rajan Kumar Pandey, Priyanka Prajapati, Sukriti Goyal, Abhinav Grover and Vijay Kumar Prajapati
DOI: 10.2174/1386207319666160907100134
δ-Cadinene,Calarene and δ-4-Carene from Kadsura heteroclita Essential Oil as Novel Larvicides Against Malaria, Dengue and Filariasis Mosquitoes
, 2016; 19(7): 565-571.Marimuthu Govindarajan, Mohan Rajeswary and Giovanni Benelli
DOI: 10.2174/1386207319666160506123520
Analysis of the relationship between PM2.5 and lung cancer based on protein-protein interactions
, 2016; 19(2): 100-108.Yang Shu, Liucun Zhu, Fei Yuan, Xiangyin Kong, Tao Huang and Yu-Dong Cai
DOI: 10.2174/1386207319666151110123345
Determining Partition Coefficient (Log P), Distribution Coefficient (Log D) and Ionization Constant (pKa) in Early Drug Discovery
, 2016; 19(6): 461-469.Sonali S. Bharate, Vikas Kumar and Ram A. Vishwakarma
DOI: 10.2174/1386207319666160502123917
An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever
, 2016; 19(7): 516-536.Chelsea N. Powers and William N. Setzer*
DOI: 10.2174/1386207319666160506123715
Analysis and Prediction of Myristoylation Sites Using the mRMR Method, the IFS Method and an Extreme Learning Machine Algorithm
, 2017; 20(2): 96-106.ShaoPeng Wang, Yu-Hang Zhang, GuoHua Huang, Lei Chen* and Yu-Dong Cai*
DOI: 10.2174/1386207319666161220114424
Most Accessed Articles
Molecular Docking for Prediction and Interpretation of Adverse Drug Reactions
, 2018; 21(5): 314-322.Heng Luo, Achille Fokoue-Nkoutche, Nalini Singh, Lun Yang, Jianying Hu and Ping Zhang*
DOI: 10.2174/1386207321666180524110013
A Rapid Python-Based Methodology for Target-Focused Combinatorial Library Design
, 2016; 19(1): 25-35.Shiliang Li, Yuwei Song, Xiaofeng Liu and Honglin Li
DOI: 10.2174/1386207318666151102094055
Atom-based and Pharmacophore-based 3D – QSAR Studies on Vitamin D Receptor (VDR)
, 2018; 21(5): 329-343.Selvaraman Nagamani, Chandrasekhar Kesavan and Karthikeyan Muthusamy*
DOI: 10.2174/1386207321666180607101720
Synergistic Interplay of The Co-administration of Rifampin And Newly Developed Anti-TB Drug: Could It Be a Promising New Line of TB Therapy?
, 2018; 21(6): 453-460.Clement Agoni, Pritika Ramharack and Mahmoud E.S. Soliman*
DOI: 10.2174/1386207321666180716093617
Prediction of Nitrated Tyrosine Residues in Protein Sequences by Extreme Learning Machine and Feature Selection Methods
, 2018; 21(6): 393-402.Lei Chen*, ShaoPeng Wang, Yu-Hang Zhang, Lai Wei, XianLing Xu, Tao Huang* and Yu-Dong Cai*
DOI: 10.2174/1386207321666180531091619
An Integrated Multi-Label Classifier with Chemical-Chemical Interactions for Prediction of Chemical Toxicity Effects
, 2018; 21(6): 403-410.Tao Liu , Lei Chen* and Xiaoyong Pan
DOI: 10.2174/1386207321666180601075428
Ag/CdS Nanocomposite: An Efficient Recyclable Catalyst for the Synthesis of Novel 8-Aryl-8H-[1,3]dioxolo[4,5-g]chromene-6-carboxylic Acids under Mild Reaction Conditions
, 2018; 21(5): 323-328.Shahrzad Abdolmohammadi*, Seyed Reza Rasouli Nasrabadi, Ahmad Seif and Narges Elmi Fard
DOI: 10.2174/1386207321666180604104456
A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells
, 2018; 21(1): 50-56.F. Ricci*, L. Carrassa, M. S. Christodoulou, D. Passarella, B. Michel, R. Benhida, N. Martinet, A. Hunyadi, E. Ioannou, V. Roussis, L. Musso, S. Dallavalle, R. Silvestri, N. Westwood, M. Mori, C. Ingallina, B. Botta, E. Kavetsou, A. Detsi, Z. Majer, F. Hudecz, S. Bosze, B. Kaminska, T.V. Hansen, P. Bertrand, C. M. Athanassopoulos and G. Damia*
DOI: 10.2174/1386207321666180124093406
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