Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research
Volume 24, 10 Issues, 2021
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access
Aims & Scope
Combinatorial Chemistry & High Throughput Screening (CCHTS) publishes full length original research articles and reviews/mini-reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research. Original research articles and reviews in the following areas are of special interest to the readers of this journal:
- Target identification and validation
- Assay design, development, miniaturization and comparison
- High throughput/high content/in silico screening and associated technologies
- Label-free detection technologies and applications
- Stem cell technologies
- Biomarkers
- ADMET/PK/PD methodologies and screening
- Probe discovery and development, hit to lead optimization
- Combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries)
- Chemical library design and chemical diversity
- Chemo/bio-informatics, data mining
- Compound management
- Pharmacognosy
- Natural Products Research (Chemistry, Biology and Pharmacology of Natural Products)
- Natural Product Analytical Studies
- Bipharmaceutical studies of Natural products
- Drug repurposing
- Data management and statistical analysis
- Laboratory automation, robotics, microfluidics, signal detection technologies
- Current & Future Institutional Research Profile
- Technology transfer, legal and licensing issues
- Patents
In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discovery and development, in the settings of industry, academia or government.
Combinatorial Chemistry & High Throughput Screening
,Volume 24
-Number 5
Review Article
Cervical Cancer Diagnosis: Insights into Biochemical Biomarkers and Imaging Techniques
, 24(5): 605 - 623Fatemeh Tavakoli, Sara Sadat Khatami, Fatemeh Momeni, Javid Azadbakht* and Faezeh Ghasemi*
DOI: 10.2174/1386207323666200901101955
Cervical Cancer Diagnosis: Insights into Biochemical Biomarkers and Imaging Techniques
Review Article
Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review
, 24(5): 624 - 644Roohi Mohi-ud-din, Reyaz Hassan Mir, Prince Ahad Mir, Saeema Farooq, Syed Naiem Raza, Weekar Younis Raja, Mubashir Hussain Masoodi, Inder Pal Singh and Zulfiqar Ali Bhat*
DOI: 10.2174/1386207323999201102141206
Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review
Research Article
Screening and Identification of Differentially Expressed Genes Between Diabetic Nephropathy Glomerular and Normal Glomerular via Bioinformatics Technology
, 24(5): 645 - 655Junjie Du, Jihong Yang* and Lingbing Meng
DOI: 10.2174/1386207323999200821163314
Screening and Identification of Differentially Expressed Genes Between Diabetic Nephropathy Glomerular and Normal Glomerular via Bioinformatics Technology
Research Article
13-lncRNAs Signature to Improve Diagnostic and Prognostic Prediction of Hepatocellular Carcinoma
, 24(5): 656 - 667Xinxin Zhang, Jia Yu, Juan Hu, Fang Tan, Juan Zhou, Xiaoyan Yang, Zhizhong Xie, Huifang Tang, Sen Dong and Xiaoyong Lei*
DOI: 10.2174/1386207323666200914095616
13-lncRNAs Signature to Improve Diagnostic and Prognostic Prediction of Hepatocellular Carcinoma
Research Article
Systematic Evaluation of the Mechanisms of Mulberry Leaf (Morus alba Linne) Acting on Diabetes Based on Network Pharmacology and Molecular Docking
Research Article
Activated Carbon/MoO3: Efficient Catalyst for Green Synthesis of Chromeno[d]pyrimidinediones and Xanthenones
, 24(5): 683 - 694Niloofar Sabet Mehr, Shahrzad Abdolmohammadi* and Maryam Afsharpour
DOI: 10.2174/1386207323666200924111602
Activated Carbon/MoO3: Efficient Catalyst for Green Synthesis of Chromeno[d]pyrimidinediones and Xanthenones
Research Article
Microwave-assisted Synthesis of Novel Pyrazole Derivatives and their Biological Evaluation as Anti-Bacterial Agents
, 24(5): 695 - 700Hadis Khodadad, Farhad Hatamjafari*, Khalil Pourshamsian* and Babak Sadeghi
DOI: 10.2174/1386207323666201019152206
Microwave-assisted Synthesis of Novel Pyrazole Derivatives and their Biological Evaluation as Anti-Bacterial Agents
Research Article Open Access
Elucidation of the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based Strategy
, 24(5): 701 - 715Peiliang Wu, Xiaona Xie, Mayun Chen, Junwei Sun, Luqiong Cai, Jinqiu Wei, Lin Yang, Xiaoying Huang* and Liangxing Wang*
DOI: 10.2174/1386207323666201019145354
Elucidation of the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based Strategy
Combinatorial Chemistry & High Throughput Screening, Volume 24 (2021) - Number 7
This issue is in progress but contains articles that are final and fully citable.
Combinatorial Chemistry & High Throughput Screening, Volume 24 (2021) - Number 6
This issue is in progress but contains articles that are final and fully citable.
Articles Ahead of Print
Rapid Identification of Commercial Frankincense Products by MALDITOF Mass Spectrometry
Shang-Chih Lai, Ren-In You, Tz-Ting Chen, Yu Chang, Chao-Zong Liu, Hao-Ping Chen* and Chunhung Wu*
DOI: 10.2174/1386207324666210301092111
View Abstract View on PubMed
Enhanced Removal of Methyl Violet Dye from Aqueous Solution by a Novel Co3O4@SiO2@TiO2-Ag Heterogeneous Semiconductor
Mohammad Ali Ghasemzadeh*, Zahar Elyasi and Mohammad Reza Zand Monfared
DOI: 10.2174/1386207324666210301090123
View Abstract View on PubMed
Water Mapping and Scoring Approaches to Predict the Role of Hydration Sites in the Binding Affinity of PAK1 Inhibitors
Jayashree Biswal, Prajisha Jayaprakash, Suresh Kumar Rayala, Ganesh Venkatraman, Raghu Rangasamy, Saritha Poopandi and Jeyaraman Jeyakanthan*
DOI: 10.2174/1386207324666210308110646
View Abstract View on PubMed
A Quality by Design Approach of Metronidazole Bigel and Assessment of Antimicrobial Study Utilizing Box-Behnken Design
Harekrishna Roy*, Sudhir Maddela*, Alekhya Munagala, Shaik Abdul Rahaman and Sisir Nandi
DOI: 10.2174/1386207323666201230094115
View Abstract View on PubMed
Withdrawal Notice: Nickel (II) and oxovanadium (IV) complexes supported on MCM-41 mesoporous and their application in catalytic selective sulfide and thiol oxidation
Mohsen Nikoorazm*, Maryam Khanmoradi and Masoumeh Sayadian
DOI: 10.2174/1386207323999201111192649
View Abstract
Anti-inflammatory Activity of Mollugo cerviana Methanolic Extract in LPS-induced Acute Inflammatory RAW 264.7 Macrophages
Robina Antony, Jijin Raveendran and Prabath Gopalakrishnan Biju*
DOI: 10.2174/1386207324666210302101204
View Abstract View on PubMed
Pouteria sapota (Red Mamey Fruit): Chemistry and Biological Activity of Carotenoids
Johant Lakey-Beitia, Velmarini Vasquez, Randy Mojica-Flores, Arelys L. Fuentes C., Enrique Murillo, Muralidhar L. Hedge and K.S. Rao*
DOI: 10.2174/1386207324666210301093711
View Abstract View on PubMed
Predicting Drug-Target Affinity Based on Recurrent Neural Networks and Graph Convolutional Neural Networks
Qingyu Tian*, Mao Ding*, Hui Yang, Caibin Yue, Yue Zhong, Zhenzhen Du, Dayan Liu, Jiali Liu and Yufeng Deng
DOI: 10.2174/1386207324666210215101825
View Abstract View on PubMed
An Urgent Industrial Scheme Both for Total Synthesis, and for Pharmaceutical Analytical Analysis of Umifenovir as an Anti-viral API for Treatment of COVID-19
Akbar Dadras, Mohammad Amin Rezvanfar, Abolghasem Beheshti, Sedigheh Sadat Naeimi and Seyyed Amir Siadati*
DOI: 10.2174/1386207324666210203175631
View Abstract View on PubMed
Abstracts Ahead of Print
The Molecular Mechanism of Scutellaria baicalensis Georgi Stems and Leaves Flavonoids in Promoting Neurogenesis and Improving Memory Impairment by the PI3K-AKT-CREB Signaling Pathway in Rats
Qian-qian Liu, Sheng-kai Ding, Hui Zhang and Ya-zhen Shang*
DOI: 10.2174/1386207324666210506152320
View Abstract
Mechanism of action of strychni semen for treating Rheumatoid arthritis and methods for attenuating the toxicity
Yuling Li, Yifan Liu, Yumeng Shao, Fengcong Zhang, Weidong Liu, Xiaodong Liang* and Li Chen*
DOI: 10.2174/1386207324666210504095523
View Abstract
Current Application of Chemometrics Analysis in Authentication of Natural Products: A Review
Abdelkrim Rebiai, Hadia Hemmami, Soumeia Zeghoud, Bachir Ben Seghir*, Imane Kouadri, Laouini Salah Eddine, Noureddine Elboughdiri, Saad Ghareba, Djamel Ghernaout and Nadir Abbas
DOI: 10.2174/1386207324666210309102239
View Abstract
MHD flow of a Newtonian fluid in symmetric channel with ABC fractional model containing hybrid nanoparticles
Muhammad Danish Ikram, Muhammad Asjad Imran, Yu Ming Chu and Ali Akgül*
DOI: 10.2174/1386207324666210412122544
View Abstract
Nutraceuticals with anti-inflammatory and anti-oxidant properties as intervention for reducing the health effects of fine particulate matter: Potential and Prospects
Tanwi Trushna, Amit K. Tripathi, Sindhuprava Rana* and Rajnarayan R. Tiwari
DOI: 10.2174/1386207324666210412121226
View Abstract
FEN1 status and its correlation with clinicopathologic characteristic in colorectal cancer
Yundi Guo*, Zixuan Du *, Yuanshuai Zhou, Haijun Sun, Rui Liang, Min-Xuan Sun, Zaixiang Tang and Song-Bai Liu
DOI: 10.2174/1386207324666210401113351
View Abstract
Combinatorial Synthesis of Novel 3/5(3,5)-(Di)nitro/chloropaeonol Carbonyl Hydrazone Derivatives as Nematicidal Agents
Genqiang Chen, Lina Zhu, Yanfei Xia, Song Zhang, Yuanhao Li, Xiaolong Guo, Di Sun, Jiaxuan He, Yuee Tian, Shengming Liu, Jia Jiang and Zhiping Che*
DOI: 10.2174/1386207324666210324145627
View Abstract
3-T MRI in Patients Received Anterior Cervical Discectomy and Fusion Surgery with MAVRIC SL IR Sequence: A Feasibility Study
Renjie Yang, Changsheng Liu, Liang Li, Liang Chen, Weiyin Vivian Liu and Yunfei Zha*
DOI: 10.2174/1386207324666210322125827
View Abstract
GCSF As a Potential Molecular Target for Overall Survival of Hepatocellular Carcinoma
Heng Cao, Peng Guo, Xiaohui Wu, Jiankun Li, Chenlong Ge and Shunxiang Wang*
DOI: 10.2174/1386207324666210322124003
View Abstract
Anti-inflammatory assessment of 3-Acetylmyricadiol in LPS-Stimulated Raw 264.7 Macrophages
Gazanfar Ahmad, Reyaz Hassan, Neerupma Dhiman* and Asif Ali*
DOI: 10.2174/1386207324666210319122650
View Abstract
Published Contents
Editor's Choice
Cervical Cancer Diagnosis: Insights into Biochemical Biomarkers and Imaging Techniques
, 2021; 24(5): 605 - 623Fatemeh Tavakoli, Sara Sadat Khatami, Fatemeh Momeni, Javid Azadbakht* and Faezeh Ghasemi*
DOI: 10.2174/1386207323666200901101955
Could Targeting HMGB1 be Useful for the Clinical Management of COVID-19 Infection?
, 2021; 24(4): 587 - 590Mustafa Çelebier and İbrahim Celalettin Haznedaroğlu*
DOI: 10.2174/1386207323999200728114927
Electrochemical Behavior and Square-Wave Stripping Voltammetric Determination of Roflumilast in Pharmaceutical Dosage Forms
, 2021; 24(3): 400 - 408Mustafa Çelebier, Aysegul Dogan, İncilay Süslü* and Sacide Altınöz
DOI: 10.2174/1386207323666200901102526
An Insight into Unani Hypoglycemic Drugs and Their Mechanism of Action
, 2021; 24(2): 165 - 176Mohammad Fazil, Sadia Nikhat and Imran Ali*
DOI: 10.2174/1386207323666200717143540
Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans
, 2021; 24(1): 109 - 118Eti Apriyanti, Mieke H. Satari and Dikdik Kurnia*
DOI: 10.2174/1386207323666200628111348
Host-directed Therapy: A New Arsenal to Come
, 2021; 24(1): 59 - 70Mradul Mohan* and Debapriya Bhattacharya*
DOI: 10.2174/1386207323999200728115857
Rhodamine B - as New Chromophore for the Determination of Melatonin in Biological, Food, and Pharmaceutical Samples
, 2020; 23(10): 1080 - 1089Alexandrina Lungu-Moscalu, Catalina C. Negut, Cristina Stefanov, Raluca-Ioana S. van Staden*, Andrei A. Bunaciu and Jacobus F. van Staden
DOI: 10.2174/1386207323666200628111958
Inhibition of Cyclooxygenase Enzyme by Bioflavonoids in Horsegram Seeds Alleviates Pain and Inflammation
, 2020; 23(9): 931 - 938Malarvizhi Ramalingam, Veeresh K. Sali, Meenakshi Bhardwaj, Sugumar Mani and Hannah R. Vasanthi*
DOI: 10.2174/1386207323666200127114551
Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study
, 2020; 23(8): 723 - 739Avinash Patil, Harleen Duggal, Kamini T. Bagul, Sonali Kamble, Pradeep Lokhande*, Rajesh Gacche* and Rohan Meshram*
DOI: 10.2174/1386207323666200422082754
Synthesis, Conformational Analysis, Infrared, Raman and UV-Visible Spectra of Novel Schiff Bases compiled with DFT Calculations
, 2020; 23(7): 568 - 586Samy M. Ahmed, Ibrahim A. Shaaban, Elsayed H. El-Mossalamy and Tarek A. Mohamed*
DOI: 10.2174/1386207323666200127161207
Open Access Articles
Analysis of Chinese Herbal Formulae Recommended for COVID-19 in Different Schemes in China: A Data Mining Approach
, 2021; 24(7): 957 - 967LiWei Yin, YaCen Gao, ZiPing Li*, MengYu Wang and KaiXin Chen
Elucidation of the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based Strategy
, 2021; 24(5): 701 - 715Peiliang Wu, Xiaona Xie, Mayun Chen, Junwei Sun, Luqiong Cai, Jinqiu Wei, Lin Yang, Xiaoying Huang* and Liangxing Wang*
Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans
, 2021; 24(1): 109 - 118Eti Apriyanti, Mieke H. Satari and Dikdik Kurnia*
Synthesis of Eicosapentaenoic Acid-enriched Phosphatidylcholine and its Effect on Pro-inflammatory Cytokine Expression
, 2021; 24: 1 - 6 (E-Pub Ahead of Print)Jae Yeul Baek, Eun Na and Sun Young Lim*
Exploring miRNA-related Molecular Targets of Erchen Decoction Against Lipid Metabolism Disorder using A Network Pharmacologic Approach
, 2021; 24: 1 - 12 (E-Pub Ahead of Print)Shanshan Ding, Qiliang Chen, Yiqing Huang, Xiaomei Li, Yujuan Chai, Candong Li and Tetsuya Asakawa*
KDS2010: A Potent Highly Selective and Reversible MAO-B Inhibitor for Alzheimer’s Disease
, 2020; 23(9): 836 - 841Abdullah Al Mamun and Md. Sahab Uddin*
Network Pharmacology-based Investigation of the Underlying Mechanism of Panax notoginseng Treatment of Diabetic Retinopathy
, 2020; 23(4): 334 - 344Chunli Piao*, Zheyu Sun, De Jin, Han Wang, Xuemin Wu, Naiwen Zhang, Fengmei Lian* and Xiaolin Tong*
An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology
, 2020; 23(3): 239 - 252Sizhen Gu, Yan Xue, Yuli Zhang, Kanjun Chen, Shigui Xue, Ji Pan, Yini Tang, Hui Zhu, Huan Wu and Danbo Dou*
Transcriptome Analysis of FEN1 Knockdown HEK293T Cell Strain Reveals Alteration in Nucleic Acid Metabolism, Virus Infection, Cell Morphogenesis and Cancer Development
, 2019; 22(6): 379 - 386Song-Bai Liu*, Xiu-Qin Qiu, Wei-Qiang Guo, Jin-Li Li, Qian Su, Jia-Hui Du, He-Juan Hu, Xiao-Xiao Wang, Yao-Hua Song, Xiao Lou* and Xiang-Bin Xu*
Effect of the Phragmitis Rhizoma Aqueous Extract on the Pharmacokinetics of Docetaxel in Rats
, 2019; 22(5): 326 - 332Sarah Shin, No Soo Kim, Young Ah Kim, Hea Ry Oh and Ok-Sun Bang*
Integrative Analysis of Dysfunctional Modules Driven by Genomic Alterations at System Level Across 11 Cancer Types
, 2018; 21(10): 771 - 783Yin Wang, Zhenhao Liu, Baofeng Lian*, Lei Liu* and Lu Xie*
A Network Integration Method for Deciphering the Types of Metabolic Pathway of Chemicals with Heterogeneous Information
, 2018; 21(9): 670 - 680Zi-Han Guo, Lei Chen* and Xian Zhao
Protein Sequence Comparison and DNA-binding Protein Identification with Generalized PseAAC and Graphical Representation
, 2018; 21(2): 100 - 110Chun Li*, Jialing Zhao, Changzhong Wang and Yuhua Yao
High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review
, 2016; 19(8): 605 - 615Carlina Peña-García, Mónica Martínez-Martínez, Dolores Reyes-Duarte* and Manuel Ferrer*
An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever
, 2016; 19(7): 516 - 536Chelsea N. Powers and William N. Setzer*
Most Cited Articles
Perspective
Kds2010: A potent highly selective and reversible mao-b inhibitor for alzheimer’s disease
, 2020; 23(9): 836-841.Abdullah Al Mamun and Md. Sahab Uddin*
DOI: 10.2174/1386207323666200117103144
Research Article
Drug target group prediction with multiple drug networks
, 2020; 23(4): 274-284.Jingang Che, Lei Chen*, Zi-Han Guo, Shuaiqun Wang and Aorigele
DOI: 10.2174/1386207322666190702103927
Research Article
Design and fabrication of a magnetite-based polymer-supported hybrid nanocomposite: A promising heterogeneous catalytic system utilized in known palladium-assisted coupling reactions
, 2020; 23(2): 119-125.Ali Maleki*, Reza Taheri-Ledari and Reza Ghalavand
DOI: 10.2174/1386207323666200128152136
Research Article
Green route for the removal of pb from aquatic environment
, 2020; 23(7): 587-598.Ahmed Refaat*, Hanan Elhaes, Nabila S. Ammar, Hanan S. Ibrahim and Medhat Ibrahim
DOI: 10.2174/1386207323666200127123349
Research Article
Three major phosphoacceptor sites in HIV-1 capsid protein enhances its structural stability and resistance against the inhibitor: Explication through molecular dynamics simulation, molecular docking and DFT analysis
, 2020; 23(1): 41-54.Nouman Rasool* and Waqar Hussain
DOI: 10.2174/1386207323666191213142223
Editorial
Nanoinformatics: Artificial intelligence and nanotechnology in the new decade
, 2020; 23(1): 4-5.Antreas Afantitis
DOI: 10.2174/138620732301200316112000
Research Article
The use of texture features to extract and analyze useful information from retinal images
, 2020; 23(4): 313-318.Xiaobo Zhang, Weiyang Chen*, Gang Li* and Weiwei Li
DOI: 10.2174/1386207322666191022123445
Research Article
Theoretical study of the molecular mechanism of maxingyigan decoction against covid-19: Network pharmacology-based strategy
, 2021; 24(2): 294-305.Mingzhu Wang, Deyu Fu*, Lei Yao and Jianhua Li
DOI: 10.2174/1386207323666200806164635
Research Article
Lignans and neolignans anti-tuberculosis identified by qsar and molecular modeling
, 2020; 23(6): 504-516.Mayara S. Maia, Natália F. de Sousa, Gabriela C.S. Rodrigues, Alex F.M. Monteiro, Marcus T. Scotti and Luciana Scotti*
DOI: 10.2174/1386207323666200226094940
Research Article
Comprehensive bioinformatics analysis identifies tumor microenvironment and immune-related genes in small cell lung cancer
, 2020; 23(5): 381-391.Yongchun Song, Yanqin Sun, Tuanhe Sun and Ruixiang Tang*
DOI: 10.2174/1386207323666200407075004
Research Article
Synthesis, spectroscopic, in-vitro and computational analysis of hydrazones as potential antituberculosis agents: (part-I)
, 2020; 23(5): 392-401.Bapu R. Thorat*, Deepa Rani, Ramesh S. Yamgar and Suraj N. Mali*
DOI: 10.2174/1386207323999200325125858
Research Article
Novel thiazole-based thiazolidinones as potent anti-infective agents: In silico PASS and toxicity prediction, synthesis, biological evaluation and molecular modelling
, 2020; 23(2): 126-140.Christophe Tratrat*
DOI: 10.2174/1386207323666200127115238
General Research Article
Discovery of potent sars-cov-2 inhibitors from approved antiviral drugs via docking and virtual screening
, 2021; 24(3): 441-454.Samir Chtita *, Assia Belhassan, Adnane Aouidate, Salah Belaidi, Mohammed Bouachrine and Tahar Lakhlifi
DOI: 10.2174/1386207323999200730205447
Perspective
Privileged pharmacophore of FDA approved drugs in combination with chalcone framework: A new hope for Alzheimer’s treatment
, 2020; 23(9): 842-846.Bijo Mathew*
DOI: 10.2174/1386207323999200728122627
Research Article
Inhibition of cyclooxygenase enzyme by bioflavonoids in horsegram seeds alleviates pain and inflammation
, 2020; 23(9): 931-938.Malarvizhi Ramalingam, Veeresh K. Sali, Meenakshi Bhardwaj, Sugumar Mani and Hannah R. Vasanthi*
DOI: 10.2174/1386207323666200127114551
Most Accessed Articles
Computational Method for Identifying Malonylation Sites by Using Random Forest Algorithm
, 2020; 23(4): 304-312.ShaoPeng Wang, JiaRui Li, Xijun Sun, Yu-Hang Zhang, Tao Huang* and Yudong Cai*
DOI: 10.2174/1386207322666181227144318
A Study on the Mechanism of Lavender in the Treatment of Insomnia Based on Network Pharmacology
, 2020; 23(5): 419-432.Yao Wang, Junbo Zou, Yanzhuo Jia, Yulin Liang, Xiaofei Zhang*, Chang-Li Wang, Xiao Wang*, Dongyan Guo, Yajun Shi and Ming Yang
DOI: 10.2174/1386207323666200401095008
Virtual Screening of the Multi-pathway and Multi-gene Regulatory Molecular Mechanism of Dachengqi Decoction in the Treatment of Stroke Based on Network Pharmacology
, 2020; 23(8): 775-787.Lishan Pei, Xia Shen, Yonggang Yan*, Conge Tan*, Kai Qu, Junbo Zou, Yanxia Wang and Fan Ping
DOI: 10.2174/1386207323666200311113747
The Identification of Three Key Genes Related to Stemness in Thyroid Carcinoma through Comprehensive Analysis
, 2021; 24(3): 423-432.Tonglong Zhang, Chunhong Yan, Zhengdu Ye, Xingling Yin and Tian-an Jiang*
DOI: 10.2174/1386207323666200806164003
In vitro and in silico Xanthine Oxidase Inhibitory Activity of Selected Phytochemicals Widely Present in Various Edible Plants
, 2020; 23(9): 917-930.Arshad Mehmood, Ashfaq Ur Rehman, Muhammad Ishaq, Liang Zhao, Jiayi Li, Muhammad Usman, Lei Zhao*, Abdur Rehman, Oumeddour D. Zad and Chengtao Wang*
DOI: 10.2174/1386207323666200428075224
Discovery of Potent SARS-CoV-2 Inhibitors from Approved Antiviral Drugs via Docking and Virtual Screening
, 2021; 24(3): 441-454.Samir Chtita *, Assia Belhassan, Adnane Aouidate, Salah Belaidi, Mohammed Bouachrine and Tahar Lakhlifi
DOI: 10.2174/1386207323999200730205447
Elucidation of the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based Strategy
, 2021; 24(5): 701-715.Peiliang Wu, Xiaona Xie, Mayun Chen, Junwei Sun, Luqiong Cai, Jinqiu Wei, Lin Yang, Xiaoying Huang* and Liangxing Wang*
DOI: 10.2174/1386207323666201019145354
Molecular Docking and Virtual Screening based prediction of drugs for COVID-19
, 2021; 24(5): 716-728.Sekhar Talluri*
DOI: 10.2174/1386207323666200814132149
KDS2010: A Potent Highly Selective and Reversible MAO-B Inhibitor for Alzheimer’s Disease
, 2020; 23(9): 836-841.Abdullah Al Mamun and Md. Sahab Uddin*
DOI: 10.2174/1386207323666200117103144
A Recent Look into Natural Products that have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update for 2010-2019
, 2020; 23(9): 862-876.Hayrettin O. Gulcan and Ilkay E. Orhan*
DOI: 10.2174/1386207323666200127145246
Theoretical Study of the Molecular Mechanism of Maxingyigan Decoction Against COVID-19: Network Pharmacology-based Strategy
, 2021; 24(2): 294-305.Mingzhu Wang, Deyu Fu*, Lei Yao and Jianhua Li
DOI: 10.2174/1386207323666200806164635
The Development of Spectrophotometric and Validated Stability- Indicating RP-HPLC Methods for Simultaneous Determination of Ephedrine HCL, Naphazoline HCL, Antazoline HCL, and Chlorobutanol in Pharmaceutical Pomade Form
, 2020; 23(10): 1090-1099.Çiğdem K. Dindar, Cem Erkmen, Bengi Uslu* and Nilgün G. Göğer*
DOI: 10.2174/1386207323666200720101835
A Sequence-Based Predictor of Zika Virus Proteins Developed by Integration of PseAAC and Statistical Moments
, 2020; 23(8): 797-804.Waqar Hussain, Nouman Rasool* and Yaser D. Khan
DOI: 10.2174/1386207323666200428115449
Editor-in-Chief
Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)
Biography
LiS Consulting, Lawrence
KS
Biography
Biography of Gerald H. Lushington
Dr. Gerald Lushington received his Ph.D. in Chemistry from the University of New Brunswick. The author of 181 journal articles, nine book chapters and four patents, Lushington is currently Principal Consultant at LiS Consulting, and serves as Adjunct Professor of Food Nutrition Dietetic Health at Kansas State University. With more than 25 years experience in the application of molecular modeling, simulation and informatics to a diverse range of scientific applications, Lushington's primary areas of focus are in drug discovery and pharmacology.
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Journal History
Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.
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