Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research
Volume 23, 10 Issues, 2020
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access
In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research
Aims & Scope
Combinatorial Chemistry & High Throughput Screening (CCHTS) publishes full length original research articles and reviews/mini-reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research. Original research articles and reviews in the following areas are of special interest to the readers of this journal:
- Target identification and validation
- Assay design, development, miniaturization and comparison
- High throughput/high content/in silico screening and associated technologies
- Label-free detection technologies and applications
- Stem cell technologies
- Biomarkers
- ADMET/PK/PD methodologies and screening
- Probe discovery and development, hit to lead optimization
- Combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries)
- Chemical library design and chemical diversity
- Chemo/bio-informatics, data mining
- Compound management
- Pharmacognosy
- Natural Products Research (Chemistry, Biology and Pharmacology of Natural Products)
- Natural Product Analytical Studies
- Bipharmaceutical studies of Natural products
- Drug repurposing
- Data management and statistical analysis
- Laboratory automation, robotics, microfluidics, signal detection technologies
- Current & Future Institutional Research Profile
- Technology transfer, legal and licensing issues
- Patents
In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discovery and development, in the settings of industry, academia or government.
Combinatorial Chemistry & High Throughput Screening
,Volume 23
-Number 8
Biography Open Access
Meet Our Editorial Board Member
Editorial Open Access
Viral Evolution will Automatically Resolve COVID-19 Pandemic
, 23(8): 686Deepak Sharma*
DOI: 10.2174/1386207323666200724150726
Viral Evolution will Automatically Resolve COVID-19 Pandemic
Review Article
Integrating Bioinformatics Strategies in Cancer Immunotherapy: Current and Future Perspectives
, 23(8): 687 - 698Houda N. Washah, Elliasu Y. Salifu, Opeyemi Soremekun, Ahmed A. Elrashedy, Geraldene Munsamy, Fisayo A. Olotu and Mahmoud E.S. Soliman*
DOI: 10.2174/1386207323666200427113734
Integrating Bioinformatics Strategies in Cancer Immunotherapy: Current and Future Perspectives
Review Article
Flaxseed for Health and Disease: Review of Clinical Trials
, 23(8): 699 - 722Mersedeh Shayan, Safa Kamalian, Amirhossein Sahebkar and Zahra Tayarani-Najaran*
DOI: 10.2174/1386207323666200521121708
Flaxseed for Health and Disease: Review of Clinical Trials
Research Article
Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study
, 23(8): 723 - 739Avinash Patil, Harleen Duggal, Kamini T. Bagul, Sonali Kamble, Pradeep Lokhande*, Rajesh Gacche* and Rohan Meshram*
DOI: 10.2174/1386207323666200422082754
Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study
Research Article
Variable Screening for Near Infrared (NIR) Spectroscopy Data Based on Ridge Partial Least Squares Regression
, 23(8): 740 - 756Naifei Zhao, Qingsong Xu, Man-lai Tang and Hong Wang*
DOI: 10.2174/1386207323666200428114823
Variable Screening for Near Infrared (NIR) Spectroscopy Data Based on Ridge Partial Least Squares Regression
Research Article
Scaffold-based Screening and Molecular Dynamics Simulation Study to Identify Two Structurally Related Phenolic Compounds as Potent MMP1 Inhibitors
, 23(8): 757 - 774Swagata Patra, Parameswaran Saravanan, Bhaskar Das, Venkatesan Subramanian and Sanjukta Patra*
DOI: 10.2174/1386207323666200428114216
Scaffold-based Screening and Molecular Dynamics Simulation Study to Identify Two Structurally Related Phenolic Compounds as Potent MMP1 Inhibitors
Research Article
Virtual Screening of the Multi-pathway and Multi-gene Regulatory Molecular Mechanism of Dachengqi Decoction in the Treatment of Stroke Based on Network Pharmacology
, 23(8): 775 - 787Lishan Pei, Xia Shen, Yonggang Yan*, Conge Tan*, Kai Qu, Junbo Zou, Yanxia Wang and Fan Ping
DOI: 10.2174/1386207323666200311113747
Virtual Screening of the Multi-pathway and Multi-gene Regulatory Molecular Mechanism of Dachengqi Decoction in the Treatment of Stroke Based on Network Pharmacology
Combinatorial Chemistry & High Throughput Screening, Volume 23 (2020) - Number 10
This issue is in progress but contains articles that are final and fully citable.
Biography Open Access
Meet Our Editorial Board Member
Editorial Open Access
Contemporary Issues on Pharmaceutical Researches
, 23(10): 989Cem Erkmen, Bengi Uslu and Sevinc Kurbanoglu
DOI: 10.2174/138620732310201127093512
Contemporary Issues on Pharmaceutical Researches
Research Article
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs using High-performance Liquid Chromatography
, 23(10): 990 - 1001Maha M. Abou El-Alamin, Maha A. Sultan, Mostafa A. Atia and Hassan Y. Aboul-Enein*
DOI: 10.2174/1386207323666200220114818
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs using High-performance Liquid Chromatography
Research Article
Anodic Adsorptive Stripping Voltammetric Determination of Rafoxanide on Glassy Carbon Electrode
, 23(10): 1002 - 1009Abd-Elgawad Radi * and Hassan El-samboskany
DOI: 10.2174/1386207323666200422083339
Anodic Adsorptive Stripping Voltammetric Determination of Rafoxanide on Glassy Carbon Electrode
Research Article
Determination of Selected Phthalates in Some Commercial Cosmetic Products by HPLC-UV
, 23(10): 1010 - 1020Emrah Dural*
DOI: 10.2174/1386207323666200630113850
Determination of Selected Phthalates in Some Commercial Cosmetic Products by HPLC-UV
Research Article
Preparation of A Magnetic Nanosensor Based on Cobalt Ferrite Nanoparticles for The Electrochemical Determination of Methyldopa in The Presence of Uric Acid
, 23(10): 1021 - 1029Khadijeh Najafi, Karim Asadpour-Zeynali* and Fariba Mollarasouli*
DOI: 10.2174/1386207323666200521123657
Preparation of A Magnetic Nanosensor Based on Cobalt Ferrite Nanoparticles for The Electrochemical Determination of Methyldopa in The Presence of Uric Acid
Research Article
The Association of CYP2D6*4 and POR*28 Polymorphisms on Mirtazapine Plasma Level in Subjects with Major Depressive Disorder and Anxiety Disorders
, 23(10): 1030 - 1039Fezile Ozdemir, Emrah Dural, Nilay Sedes Baskak, Yağmur Kır, Bora Baskak and Halt S. Suzen*
DOI: 10.2174/1386207323666200402081512
The Association of CYP2D6*4 and POR*28 Polymorphisms on Mirtazapine Plasma Level in Subjects with Major Depressive Disorder and Anxiety Disorders
Research Article
GC-MS Based Metabolic Profiling of Parkinson’s Disease with Glutathione S-transferase M1 and T1 Polymorphism in Tunisian Patients
, 23(10): 1040 - 1047Amal Rebai*, Tuba Reçber, Emirhan Nemutlu, Chahra Chbili, Sevinç Kurbanoglu, Sedef Kir, Sana B. Amor, Sibel A. Özkan and Saad Saguem
DOI: 10.2174/1386207323666200428082815
GC-MS Based Metabolic Profiling of Parkinson’s Disease with Glutathione S-transferase M1 and T1 Polymorphism in Tunisian Patients
Combinatorial Chemistry & High Throughput Screening, Volume 23 (2020) - Number 9
This issue is in progress but contains articles that are final and fully citable.
Biography Open Access
Meet Our Editorial Board Member
Editorial Open Access
Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery
, 23(9): 834 - 835Bijo Mathew and Hoon Kim
DOI: 10.2174/138620732309201127093123
Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery
Perspective
KDS2010: A Potent Highly Selective and Reversible MAO-B Inhibitor for Alzheimer’s Disease
, 23(9): 836 - 841Abdullah Al Mamun and Md. Sahab Uddin*
DOI: 10.2174/1386207323666200117103144
KDS2010: A Potent Highly Selective and Reversible MAO-B Inhibitor for Alzheimer’s Disease
Perspective Open Access
Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment
, 23(9): 842 - 846Bijo Mathew*
DOI: 10.2174/1386207323999200728122627
Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment
Review Article (Mini-Review)
Treatment of Parkinson’s Disease by MAO-B Inhibitors, New Therapies and Future challenges - A Mini-Review
, 23(9): 847 - 861Della G.T. Parambi*
DOI: 10.2174/1386207323666200402090557
Treatment of Parkinson’s Disease by MAO-B Inhibitors, New Therapies and Future challenges - A Mini-Review
Review Article
A Recent Look into Natural Products that Have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update for 2010-2019
, 23(9): 862 - 876Hayrettin O. Gulcan and Ilkay E. Orhan*
DOI: 10.2174/1386207323666200127145246
A Recent Look into Natural Products that Have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update for 2010-2019
Review Article
Vital Role of Monoamine Oxidases and Cholinesterases in Central Nervous System Drug Research: A Sharp Dissection of the Pathophysiology
, 23(9): 877 - 886Begum E. Aksoz* and Erkan Aksoz
DOI: 10.2174/1386207323666200220115154
Vital Role of Monoamine Oxidases and Cholinesterases in Central Nervous System Drug Research: A Sharp Dissection of the Pathophysiology
Review Article
Quantitative Structure-Activity Relationship (QSAR) Studies for the Inhibition of MAOs
, 23(9): 887 - 897Muthusamy Ramesh* and Arunachalam Muthuraman*
DOI: 10.2174/1386207323666200324173231
Quantitative Structure-Activity Relationship (QSAR) Studies for the Inhibition of MAOs
Articles Ahead of Print
Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review
Roohi Mohi-ud-din, Reyaz Hassan Mir, Prince Ahad Mir, Saeema Farooq, Syed Naiem Raza, Weekar Younis Raja, Mubashir Hussain Masoodi, Inder Pal Singh and Zulfiqar Ali Bhat*
DOI: 10.2174/1386207323999201102141206
View Abstract View on PubMed
Comprehensive Analysis of Transcriptomics and Metabolomics between the Heads and Tails of Angelica Sinensis: Genes Related to Phenylpropanoid Biosynthesis Pathway
Jie Yang, Chi Zhang, Wei-Hong Li, Tian-Er Zhang, Guang-Zhong Fan, Bu-Fa Guo, Wei-Yi Yao, Di-Hong Gong, Qi-Lun Peng and Wei-Jun Ding*
DOI: 10.2174/1386207323999201103221952
View Abstract View on PubMed
Thiol/Disulfide Homeostasis as an Early Biomarker to Differentiate Sepsis from Pneumonia in Intensive Care Units
Esra Cakir*, Gamze Gok, Ozcan Erel and Isil Ozkocak Turan
DOI: 10.2174/1386207323999201029120333
View Abstract View on PubMed
Some Valency Oriented Molecular Invariants of Certain Networks
Muhammad Salman, Faisal Ali, Masood Ur Rehman* and Imran Khalid
DOI: 10.2174/1386207323666201020145239
View Abstract View on PubMed
Correlative Study of Bone-Related Biochemicals and Endocrine Changes in Perimenopausal Women in Enugu, Nigeria
Chinwe Ifeoma Ikegwuonu, Ikenna Kingsley Uchendu* and Chukwudi Ignatius Maduka
DOI: 10.2174/1386207323666201023120212
View Abstract View on PubMed
The Influence of Diabetes Mellitus on Rotator Cuff Repair: A Systematic Review and Meta-analysis
Xiaomin Lu, He Sun, YiSheng Xu* and Xuewei Cao
DOI: 10.2174/1386207323666201020114034
View Abstract View on PubMed
Chitosan and Wnt/β-catenin Signaling Pathways in Different Cancers
Masoumeh Eslahi, Fatemeh Sadoughi, Zatollah Asemi, Bahman Yousefi, Mohammad Ali Mansournia and Jamal Hallajzadeh*
DOI: 10.2174/1386207323666201020105736
View Abstract View on PubMed
Synthesis of Kit-6 Magnetite Silica Nanocomposite Functionalized by Amine Group for Removal of Carmoisine Dye from Aqueous Solutions
Seyedeh Mahsa Seyed Danesh, Shahab Shariati* and Hossein Faghihian
DOI: 10.2174/1386207323666201007153747
View Abstract View on PubMed
Analysis of miRNA-mRNA interaction network reveals gap junction beta 2 as a potential candidate gene involved in psoriatic hearing loss pathogenesis
Queping Liu, Lisha Wu, Chuanjian Lu and Dinghong Wu*
DOI: 10.2174/1386207323999201124204755
View Abstract
Identification of Crucial Genes and Diagnostic Value Analysis in Major Depressive Disorder Using Bioinformatics Analysis
Yao Gao, Huiliang Zhao, Teng Xu, Junsheng Tian* and Xuemei Qin
DOI: 10.2174/1386207323999201124204413
View Abstract
Abstracts Ahead of Print
There are currently no Abstracts Ahead of Print available for this journal.
Published Contents
-
Combinatorial Chemistry & High Throughput Screening, Volume 23, 2020
- Issue number 10 [Issue in Progress] : This issue is in progress but contains articles that are final and fully citable.
- Issue number 9 [Issue in Progress] : This issue is in progress but contains articles that are final and fully citable.
- Issue number 8
- Issue number 7 [Thematic Issue]
- Issue number 6 [Thematic Issue]
- Issue number 5
- Issue number 4 [Thematic Issue]
- Issue number 3
- Issue number 2
- Issue number 1
- Combinatorial Chemistry & High Throughput Screening, Volume 22, 2019
- Combinatorial Chemistry & High Throughput Screening, Volume 21, 2018
- Combinatorial Chemistry & High Throughput Screening, Volume 20, 2017
- Combinatorial Chemistry & High Throughput Screening, Volume 19, 2016
- Combinatorial Chemistry & High Throughput Screening, Volume 18, 2015
- Combinatorial Chemistry & High Throughput Screening, Volume 17, 2014
- Combinatorial Chemistry & High Throughput Screening, Volume 16, 2013
- Combinatorial Chemistry & High Throughput Screening, Volume 15, 2012
- Combinatorial Chemistry & High Throughput Screening, Volume 14, 2011
- Combinatorial Chemistry & High Throughput Screening, Volume 13, 2010
- Combinatorial Chemistry & High Throughput Screening, Volume 12, 2009
- Combinatorial Chemistry & High Throughput Screening, Volume 11, 2008
- Combinatorial Chemistry & High Throughput Screening, Volume 10, 2007
- Combinatorial Chemistry & High Throughput Screening, Volume 9, 2006
- Combinatorial Chemistry & High Throughput Screening, Volume 8, 2005
- Combinatorial Chemistry & High Throughput Screening, Volume 7, 2004
- Combinatorial Chemistry & High Throughput Screening, Volume 6, 2003
- Combinatorial Chemistry & High Throughput Screening, Volume 5, 2002
- Combinatorial Chemistry & High Throughput Screening, Volume 4, 2001
- Combinatorial Chemistry & High Throughput Screening, Volume 3, 2000
Editor's Choice
Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study
, 2020; 23(8): 723 - 739Avinash Patil, Harleen Duggal, Kamini T. Bagul, Sonali Kamble, Pradeep Lokhande*, Rajesh Gacche* and Rohan Meshram*
DOI: 10.2174/1386207323666200422082754
Synthesis, Conformational Analysis, Infrared, Raman and UV-Visible Spectra of Novel Schiff Bases compiled with DFT Calculations
, 2020; 23(7): 568 - 586Samy M. Ahmed, Ibrahim A. Shaaban, Elsayed H. El-Mossalamy and Tarek A. Mohamed*
DOI: 10.2174/1386207323666200127161207
iSP-RAAC: Identify Secretory Proteins of Malaria Parasite Using Reduced Amino Acid Composition
, 2020; 23(6): 536 - 545Haoyue Zhang, Qilemuge Xi, Shenghui Huang, Lei Zheng, Wuritu Yang* and Yongchun Zuo*
DOI: 10.2174/1386207323666200402084518
Synthesis, Antitumor Activity and Molecular Docking Studies on Seven Novel Thiazacridine Derivatives
, 2020; 23(5): 359 - 368Marcel L. Almeida, Douglas C.F. Viana , Valécia C.M. da Costa, Flaviana A. dos Santos, Michelly C. Pereira, Maira G.R. Pitta , Moacyr J.B. de Melo Rêgo, Ivan R. Pitta and Marina G.R. Pitta*
DOI: 10.2174/1386207323666200319105239
Drug Target Group Prediction with Multiple Drug Networks
, 2020; 23(4): 274 - 284Jingang Che, Lei Chen*, Zi-Han Guo, Shuaiqun Wang and Aorigele
DOI: 10.2174/1386207322666190702103927
Design and Fabrication of a Magnetite-based Polymer-supported Hybrid Nanocomposite: A Promising Heterogeneous Catalytic System Utilized in Known Palladium-assisted Coupling Reactions
, 2020; 23(2): 119 - 125Ali Maleki*, Reza Taheri-Ledari and Reza Ghalavand
DOI: 10.2174/1386207323666200128152136
Network Pharmacology Analysis on Zhichan Powder in the Treatment of Parkinson's Disease
, 2020; 23(1): 28 - 40Jia Li, Xinchang Qi, Yajuan Sun, Yingyu Zhang and Jiajun Chen*
DOI: 10.2174/1386207323666200102124302
Synthesis of 2-Substituted 4-Arylidene-5(4H)-oxazolones as Potential Cytotoxic Agents in the Presence of Lemon Juice as a Biocatalyst
, 2019; 22(9): 625 - 634Malavattu G. Prasad, Chapala V. Lakshmi, Naresh K. Katari*, Krishnan Anand, Manojit Pal* and Sreekantha B. Jonnalagadda
DOI: 10.2174/1386207322666191024105150
New Amine and Aromatic Substituted Analogues of Phencyclidine: Synthesis and Determination of Acute and Chronic Pain Activities
, 2019; 22(8): 570 - 576Maryam Shokrollahi, Marjaneh Samadizadeh, Mohsen Khalili, Seyed A. Sobhanian and Abbas Ahmadi*
DOI: 10.2174/1386207322666191016152157
Screening GLP-1 Receptor Ligands from Natural Products in Herbs through High-Content Technique
, 2019; 22(7): 445 - 454Kunhao Qin, Shengting Zhang, Jie Wang, Dongbo Liu, Yingying Xiang, Xiuling Ji and Yunlin Wei*
DOI: 10.2174/1386207322666190919143735
Open Access Articles
Network Pharmacology-based Investigation of the Underlying Mechanism of Panax notoginseng Treatment of Diabetic Retinopathy
, 2020; 23(4): 334 - 344Chunli Piao*, Zheyu Sun, De Jin, Han Wang, Xuemin Wu, Naiwen Zhang, Fengmei Lian* and Xiaolin Tong*
An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology
, 2020; 23(3): 239 - 252Sizhen Gu, Yan Xue, Yuli Zhang, Kanjun Chen, Shigui Xue, Ji Pan, Yini Tang, Hui Zhu, Huan Wu and Danbo Dou*
Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans
, 2020; 23: 1 - 10 (E-Pub Ahead of Print)Eti Apriyanti, Mieke H. Satari and Dikdik Kurnia*
Elucidation of the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based Strategy
, 2020; 23: 1 - 15 (E-Pub Ahead of Print)Peiliang Wu, Xiaona Xie, Mayun Chen, Junwei Sun, Luqiong Cai, Jinqiu Wei, Lin Yang, Xiaoying Huang and Liangxing Wang*
Transcriptome Analysis of FEN1 Knockdown HEK293T Cell Strain Reveals Alteration in Nucleic Acid Metabolism, Virus Infection, Cell Morphogenesis and Cancer Development
, 2019; 22(6): 379 - 386Song-Bai Liu*, Xiu-Qin Qiu, Wei-Qiang Guo, Jin-Li Li, Qian Su, Jia-Hui Du, He-Juan Hu, Xiao-Xiao Wang, Yao-Hua Song, Xiao Lou* and Xiang-Bin Xu*
Effect of the Phragmitis Rhizoma Aqueous Extract on the Pharmacokinetics of Docetaxel in Rats
, 2019; 22(5): 326 - 332Sarah Shin, No Soo Kim, Young Ah Kim, Hea Ry Oh and Ok-Sun Bang*
Integrative Analysis of Dysfunctional Modules Driven by Genomic Alterations at System Level Across 11 Cancer Types
, 2018; 21(10): 771 - 783Yin Wang, Zhenhao Liu, Baofeng Lian*, Lei Liu* and Lu Xie*
A Network Integration Method for Deciphering the Types of Metabolic Pathway of Chemicals with Heterogeneous Information
, 2018; 21(9): 670 - 680Zi-Han Guo, Lei Chen* and Xian Zhao
Protein Sequence Comparison and DNA-binding Protein Identification with Generalized PseAAC and Graphical Representation
, 2018; 21(2): 100 - 110Chun Li*, Jialing Zhao, Changzhong Wang and Yuhua Yao
High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review
, 2016; 19(8): 605 - 615Carlina Peña-García, Mónica Martínez-Martínez, Dolores Reyes-Duarte* and Manuel Ferrer*
An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever
, 2016; 19(7): 516 - 536Chelsea N. Powers and William N. Setzer*
Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library
, 2016; 19(4): 262 - 274Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh G. Santos, Marc A. Giulianotti and Robert J. Deschenes*
Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
, 2015; 18(1): 3 - 17Arjan J. van Adrichem, Annika Fagerholm, Laura Turunen, Anna Lehto, Jani Saarela, Ari Koskinen, Gretchen A. Repasky and Krister Wennerberg*
Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening
, 2014; 17(1): 80 - 88Benjamin Rappaz, Billy Breton, Etienne Shaffer and Gerardo Turcatti*
Chemical Informatics and the Drug Discovery Knowledge Pyramid
, 2013; 16(10): 764 - 776Gerald H. Lushington*, Yinghua Dong and Bhargav Theertham
Most Cited Articles
Research Article
Drug target group prediction with multiple drug networks
, 2020; 23(4): 274-284.Jingang Che, Lei Chen*, Zi-Han Guo, Shuaiqun Wang and Aorigele
DOI: 10.2174/1386207322666190702103927
Review Article
Progress in molecularly imprinted polymers for biomedical applications
, 2019; 22(2): 78-88.Jane Ru Choi*, Kar Wey Yong*, Jean Yu Choi and Alistair C. Cowie
DOI: 10.2174/1386207322666190325115526
Research Article
Design and fabrication of a magnetite-based polymer-supported hybrid nanocomposite: A promising heterogeneous catalytic system utilized in known palladium-assisted coupling reactions
, 2020; 23(2): 119-125.Ali Maleki*, Reza Taheri-Ledari and Reza Ghalavand
DOI: 10.2174/1386207323666200128152136
Research Article
Expression and significance of Th17 cells and related factors in patients with autoimmune hepatitis
, 2019; 22(4): 232-237.Jihong An*
DOI: 10.2174/1386207322666190402160455
Research Article
Green route for the removal of pb from aquatic environment
, 2020; 23(7): 587-598.Ahmed Refaat*, Hanan Elhaes, Nabila S. Ammar, Hanan S. Ibrahim and Medhat Ibrahim
DOI: 10.2174/1386207323666200127123349
Research Article
Systematic investigation of quercetin for treating cardiovascular disease based on network pharmacology
, 2019; 22(6): 411-420.Xian-Jun Wu, Xin-Bin Zhou, Chen Chen and Wei Mao *
DOI: 10.2174/1386207322666190717124507
Research Article
Three major phosphoacceptor sites in HIV-1 capsid protein enhances its structural stability and resistance against the inhibitor: Explication through molecular dynamics simulation, molecular docking and DFT analysis
, 2020; 23(1): 41-54.Nouman Rasool* and Waqar Hussain
DOI: 10.2174/1386207323666191213142223
Research Article
Identification of the active constituents and significant pathways of guizhi-shaoyao-zhimu decoction for the treatment of diabetes mellitus based on molecular docking and network pharmacology
, 2019; 22(9): 584-598.Qing Zhang, Ruolan Li, Wei Peng, Mengmeng Zhang, Jia Liu, Shujun Wei, Jiaolong Wang, Chunjie Wu, Yongxiang Gao* and Xufeng Pu*
DOI: 10.2174/1386207322666191022101613
Research Article
The key microRNAs regulated the development of non-small cell lung cancer by targeting TGF-β-induced epithelial–mesenchymal transition
, 2019; 22(4): 238-244.Gang Chen and Bo Ye*
DOI: 10.2174/1386207322666190410151945
Research Article
Lignans and neolignans anti-tuberculosis identified by qsar and molecular modeling
, 2020; 23(6): 504-516.Mayara S. Maia, Natália F. de Sousa, Gabriela C.S. Rodrigues, Alex F.M. Monteiro, Marcus T. Scotti and Luciana Scotti*
DOI: 10.2174/1386207323666200226094940
Editorial
Nanoinformatics: Artificial intelligence and nanotechnology in the new decade
, 2020; 23(1): 4-5.Antreas Afantitis
DOI: 10.2174/138620732301200316112000
Research Article
New computational tool based on machine-learning algorithms for the identification of rhinovirus infection-related genes
, 2019; 22(10): 665-674.Yan Xu, Yu-Hang Zhang, JiaRui Li, Xiao Y. Pan, Tao Huang* and Yu-Dong Cai*
DOI: 10.2174/1386207322666191129114741
Research Article
Effect of chinese herbal monomer hairy calycosin on nonalcoholic fatty liver rats and its mechanism
, 2019; 22(3): 194-200.Xiang Liu, Zhi-Hong Xie, Chen-Yuan Liu and Ying Zhang*
DOI: 10.2174/1386207322666190411112814
Meta-Analysis
Efficacy and safety of robot-assisted thoracic surgery (RATS) compare with video-assisted thoracoscopic surgery (VATS) for lung lobectomy in patients with non-small cell lung cancer
, 2019; 22(3): 169-178.Xun Hu and Ming Wang*
DOI: 10.2174/1386207322666190411113040
Meta-Analysis
Video-assisted thoracoscopic surgery versus thoracotomy for non-small cell lung cancer: A meta-analysis
, 2019; 22(3): 187-193.Bo Ye and Ming Wang*
DOI: 10.2174/1386207322666190415103030
Most Accessed Articles
The Multicomponent Reactions and their Libraries for Natural and Preparative Chemistry
, 2001; 4(1): 1-34.I. Ugi and S. Heck
DOI: 10.2174/1386207013331291
Network Pharmacology-based Investigation of the Underlying Mechanism of Panax notoginseng Treatment of Diabetic Retinopathy
, 2020; 23(4): 334-344.Chunli Piao*, Zheyu Sun, De Jin, Han Wang, Xuemin Wu, Naiwen Zhang, Fengmei Lian* and Xiaolin Tong*
DOI: 10.2174/1386207323666200305093709
Relating Substructures and Side Effects of Drugs with Chemical-chemical Interactions
, 2020; 23(4): 285-294.Bo Zhou*, Xian Zhao, Jing Lu, Zuntao Sun, Min Liu, Yilu Zhou, Rongzhi Liu and Yihua Wang
DOI: 10.2174/1386207322666190702102752
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Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores
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Editor-in-Chief
Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)
Biography
LiS Consulting, Lawrence
KS
Biography
Biography of Gerald H. Lushington
Dr. Gerald Lushington received his Ph.D. in Chemistry from the University of New Brunswick. The author of 181 journal articles, nine book chapters and four patents, Lushington is currently Principal Consultant at LiS Consulting, and serves as Adjunct Professor of Food Nutrition Dietetic Health at Kansas State University. With more than 25 years experience in the application of molecular modeling, simulation and informatics to a diverse range of scientific applications, Lushington's primary areas of focus are in drug discovery and pharmacology.
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Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.33
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