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Abstracted/Indexed in


"This journal is the definitive source for the most meaningful and critical information available on CNS drug targets and progress both in industrial and academic based neurodegeneration research."

Rudolf E. Tanzi
Harvard Medical School, USA

Forthcoming Special Issues

Current Perspective on Anti-Neurodegenerative Disorder’s Investigation: Computational Approaches to Clinical Research

Guest Editor(s): Anurag Khatkar
Tentative Publication Date: February, 2018
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Special Issues - In-Press

Brain Imaging and Automatic Analysis in Neurological and Psychiatric diseases

Guest Editor(s): Yu-Dong Zhang, Ti-Fei Yuan, Zheng-Chao Dong

Published Special Issues

Editorial Advisory Board Members Special Issue

Guest Editor(s): Stephen D. Skaper

Authors' Comments
I recommend CNS Neurological Disorders & Drug Targets to neuroscientists and practicing neurologists. The papers published on this platform are always of sufficient merit and quality. It maintains the highest standards of peer review, preserving the integrity of science

Abdelrahman Ibrahim Abushouk
(Faculty of Medicine, Ain Shams University, Cairo, Egypt)

CNS & Neurological Disorders - Drug Targets


Volume 17


Number 8

Biography   Open Access

Review Article

Review Article

Review Article

Research Article

The Dopaminergic Dysfunction and Altered Working Memory Performance of Aging Mice Lacking Gamma-synuclein Gene

, 17(8): 604 - 607

Viktor S. Kokhan, Tat`yana G. Kokhan, Anna N. Samsonova, Vladimir P. Fisenko, Aleksey A. Ustyugov and Gjumrakch Aliev*

DOI: 10.2174/1871527317666180726095734

Research Article

In Silico Analyses for Key Genes and Molecular Genetic Mechanism in Epilepsy and Alzheimer’s Disease

, 17(8): 608 - 617

Xiao-wen Jiang, Hong-yuan Lu, Ziru Xu, Tian-yi Liu, Qiong Wu, Yue Yang, Qing-chun Zhao* and Hui-yuan Gao*

DOI: 10.2174/1871527317666180724150839

Research Article

Serum Interleukin Levels and Insulin Resistance in Major Depressive Disorder

, 17(8): 618 - 625

Hussein Kadhem Al-Hakeim, Sadiq Neama Al-Kufi, Arafat Hussein Al-Dujaili and Michael Maes*

DOI: 10.2174/1871527317666180720155300

Research Article

Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

, 17(8): 626 - 639

Heidi Ormstad*, Vesna Bryn, Robert Verkerk, Ola H. Skjeldal, Bente Halvorsen, Ola Didrik Saugstad, Jorn Isaksen and Michael Maes

DOI: 10.2174/1871527317666180720163221

CNS & Neurological Disorders - Drug Targets , Volume 17 (2018) - Number 10

This issue is in progress but contains articles that are final and fully citable.

CNS & Neurological Disorders - Drug Targets , Volume 17 (2018) - Number 9

This issue is in progress but contains articles that are final and fully citable.

Abstracts Ahead of Print

Editor's Choice

Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

, 2018; 17(8): 626 - 639

Heidi Ormstad*, Vesna Bryn, Robert Verkerk, Ola H. Skjeldal, Bente Halvorsen, Ola Didrik Saugstad, Jorn Isaksen and Michael Maes

DOI: 10.2174/1871527317666180720163221

Light-Emitting Diode (LED) Therapy Attenuates Neurotoxicity of Methanol-Induced Memory Impairment and Apoptosis in The Hippocampus

, 2018; 17(7): 528 - 538

Amir Ghanbari, Kazem Zibara, Sepideh Salari, Majid Ghareghani, Parastou Rad, Wael Mohamed, Elham Ebadi, Mohamad Malekzadeh and Hamdallah Delaviz*

DOI: 10.2174/1871527317666180703111643

Protective Effect of Kaempferol on the Transgenic Drosophila Model of Alzheimer’s Disease

, 2018; 17(6): 421 - 429

Tanveer Beg, Smita Jyoti, Falaq Naz, Rahul, Fahad Ali, Syed Kashif Ali, Ahmed Mohamed Reyad and Yasir Hasan Siddique*

DOI: 10.2174/1871527317666180508123050

Pain-Related Behavior and Brain Activation in a Cynomolgus Macaque Model of Postoperative Pain

, 2018; 17(5): 348 - 360

Aldric Hama*, Takahiro Natsume, Shin`ya Ogawa, Yuji Awaga, Ikuo Hayashi, Akihisa Matsuda and Hiroyuki Takamatsu

DOI: 10.2174/1871527317666180515121350

Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke

, 2018; 17(4): 299 - 308

Bogdan Catalin, Otilia-Constantina Rogoveanu, Ionica Pirici, Tudor Adrian Balseanu, Adina Stan, Valerica Tudorica, Maria Balea, Ion Mindrila, Carmen Valeria Albu, Guleed Mohamed, Daniel Pirici* and Dafin Fior Muresanu

DOI: 10.2174/1871527317666180425124340

Inhibition of Neurogenesis by Zika Virus Infection

, 2018; 17(2): 78 - 86

Fahim Ahmad, Amna Siddiqui, Mohammad A. Kamal and Sayed Sartaj Sohrab*

DOI: 10.2174/1871527317666180202115114

Implications of PEGylation of Carbon Nanotubes for Central Nervous System Bioavailability

, 2017; 16(9): 983 - 989

Gisele Eva Bruch, Marcos F. Cordeiro, Livia S. Gomides, Carolina Peixoto, Arthur P. Cordeiro, Lidiane Dal Bosco, Adelina P. Santos and Daniela M. Barros*

DOI: 10.2174/1871527316666170731111735

Immunomodulatory Strategies for Huntington's Disease Treatment

, 2017; 16(8): 936 - 944

Gabriela D. Colpo*, Natalia P. Rocha, Erin Fur Stimming and Antonio L. Teixeira

DOI: 10.2174/1871527316666170613084801

Open Access Articles

Physiological and Morphological Principles Underpinning Recruitment of the Cerebellar Reserve

, 2018; 17(3): 184 - 192

Shinji Kakei*, Takahiro Ishikawa, Jongho Lee, Takeru Honda and Donna S. Hoffman

Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate

, 2017; 16(6): 714 - 723

Josephine D`Alessandro, Kevin Garofalo, Ganlin Zhao, Christopher Honan, Jay Duffner, Ishan Capila, Ian Fier, Ganesh Kaundinya, Daniel Kantor and Tanmoy Ganguly*

Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for Modulating Pain-evoked Activities of Neurons in the Hippocampal CA3 Region of Rats

, 2017; 16(5): 610 - 616

Xinya Wei, Dongxiao Yang, Tiefeng Shi, Jianing Wang, Yunling Deng, Xuezhu Qiao, Chunxiao Yang* and Manying Xu*

Nanomaterials for Neurology: State-of-the-Art

, 2016; 15(10): 1306 - 1324

María Fernanda Veloz-Castillo, Rachel M. West, Jessica Cordero-Arreola, Oscar Arias-Carrión and Miguel A. Méndez-Rojas

Neurobiology of Bipolar Disorder: Abnormalities on Cognitive and Cortical Functioning and Biomarker Levels

, 2016; 15(6): 713 - 722

Alberto S. de Sá, Carlos Campos, Nuno B.F. Rocha, Ti-Fei Yuan, Flávia Paes, Oscar Arias-Carrión, Mauro G. Carta, Antonio E. Nardi, Elie Cheniaux and Sergio Machado

The Potential of Nasal Oxytocin Administration for Remediation of Autism Spectrum Disorders

, 2016; 15(5): 564 - 577

Yuko Okamoto, Makoto Ishitobi, Yuji Wada and Hirotaka Kosaka

The Effects of Testosterone Supplementation on Cognitive Functioning in Older Men.

, 2016; 15(3): 337 - 343

Eka J. Wahjoepramono, Prita R. Asih, Vilia Aniwiyanti, Kevin Taddei, Satvinder S. Dhaliwal, Stephanie J. Fuller, Jonathan Foster, Malcolm Carruthers, Giuseppe Verdile, Hamid R Sohrabi and Ralph N. Martins

Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid

, 2015; 14(10): 1343 - 1349

Evgeny E. Akkuratov, Jian Wu, David Sowa, Zahoor A. Shah and Lijun Liu

The Role of Neuroimaging in Our Understanding of the Suicidal Brain

, 2013; 12(7): 921 - 929

Stefanie Desmyter, Stijn Bijttebier and Kees van Heeringen

Most Cited Articles

Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System

, 2016; 15(3): 329-336.

Jerzy Leszek, George E. Barreto, Kazimierz Gąsiorowski, Euphrosyni Koutsouraki, Marco Ávila-Rodrigues and Gjumrakch Aliev

DOI: 10.2174/1871527315666160202125914

Recent updates on the dynamic association between oxidative stress and neurodegenerative disorders

, 2016; 15(3): 310-320.

Taqi A. Khan, Iftekhar Hassan, Ausaf Ahmad, Asma Perveen, Shazia Aman, Saima Quddusi, Ibrahim M. Alhazza, Ghulam M. Ashraf and Gjumrakch Aliev

DOI: 10.2174/1871527315666160202124518

Novel Therapeutic Strategies for Dementia

, 2016; 15(2): 141-241.

Ramón Cacabelos, Clara Torrellas, Iván Carrera, Pablo Cacabelos, Lola Corzo, Lucía Fernández-Novoa, Iván Tellado, Juan C. Carril and Gjumrakch Aliev

DOI: 10.2174/1871527315666160202121548

Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease

, 2016; 15(3): 292-300.

Juan C. Jurado-Coronel, Marco Ávila-Rodriguez, Valentina Echeverria, Oscar Alejandro Hidalgo, Janneth Gonzalez, Gjumrakch Aliev and George E. Barreto

DOI: 10.2174/1871527315666160202125519

Nanowired Drug Delivery Across the Blood-Brain Barrier in Central Nervous System Injury and Repair

, 2016; 15(9): 1092-1117.

Aruna Sharma, Preeti Menon, Dafin F. Muresanu, Asya Ozkizilcik, Z. Ryan Tian, José V. Lafuente and Hari S. Sharma

DOI: 10.2174/1871527315666160819123059

Coenzyme Q10 for Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis

, 2016; 15(1): 45-53.

Ahmed Negida, Ahmed Menshawy, Gehad El Ashal, Yasmin Elfouly, Yasmein Hani, Yasmin Hegazy, Samar El ghonimy, Samar Fouda and Yomna Rashad

DOI: 10.2174/1871527314666150821103306

A comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder.

, 2016; 15(1): 35-44.

Domenico De Berardis, Laura Orsolini, Nicola Serroni, Gabriella Girinelli, Felice Iasevoli, Carmine Tomasetti, Andrea de Bartolomeis, Monica Mazza, Alessandro Valchera, Michele Fornaro, Giampaolo Perna, Monica Piersanti, Marco Di Nicola, Marilde Cavuto, Giovanni Martinotti and Massimo Di Giannantonio

DOI: 10.2174/1871527314666150821103825

Alzheimer’s Disease Detection by Pseudo Zernike Moment and Linear Regression Classification

, 2017; 16(1): 11-15.

Shui-Hua Wang, Sidan Du, Yin Zhang, Preetha Phillips, Le-Nan Wu, Xian-Qing Chen and Yu-Dong Zhang

DOI: 10.2174/1871527315666161111123024

Most Accessed Articles

C-Abl Inhibition; A Novel Therapeutic Target for Parkinson's Disease

, 2018; 17(1): 14-21.

Abdelrahman Ibrahim Abushouk, Ahmed Negida*, Rasha Abdelsalam Elshenawy, Hossam Zein, Ali M. Hammad, Ahmed Menshawy and Wael M.Y. Mohamed

DOI: 10.2174/1871527316666170602101538

Effects of Exercise on Anxiety and Depression Disorders: Review of Meta- Analyses and Neurobiological Mechanisms

, 2014; 13(6): 1002-1014.

Mirko Wegner, Ingo Helmich, Sergio Machado, Antonio E. Nardi, Oscar Arias-Carrion and Henning Budde

DOI: 10.2174/1871527313666140612102841

Anxiety: A Systematic Review of Neurobiology, Traditional Pharmaceuticals and Novel Alternatives from Medicinal Plants

, 2014; 13(1): 150-165.

Erica Aparecida Gelfuso, Daiane Santos Rosa, Ana Lúcia Fachin, Márcia Renata Mortari, Alexandra Olimpio Siqueira Cunha and Rene Oliveira Beleboni

DOI: 10.2174/18715273113129990102

The Efficacy and Safety of Pharmacological Treatments for Post-stroke Aphasia

, 2018; 17(7): 509-521.

Xiaoyan Zhang, Bohui Shu, Dongdong Zhang, Lina Huang, Qizhi Fu and Ganqin Du*

DOI: 10.2174/1871527317666180706143051

Microglia Phenotype Diversity

, 2011; 10(1): 108-118.

M. Olah, K. Biber, J. Vinet and H. W.G.M. Boddeke

DOI: 10.2174/187152711794488575

VaD - An Integrated Framework for Cognitive Rehabilitation

, 2018; 17(1): 22-33.

Maria Balea, Dafin Muresanu*, Anton Alvarez, Volker Homberg, Ovidiu Bajenaru, Alla Guekht, Wolf-Dieter Heiss, Livia Popa, Johannes Vester, Ioana Muresanu, Codruta Birle and Dana Slavoaca

DOI: 10.2174/1871527317666180219164545

Glutamate Receptors in Microglia

, 2013; 12(6): 773-784.

Madhuvika Murugan, Eng-Ang Ling and Charanjit Kaur

DOI: 10.2174/18715273113126660174

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