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Endorsements

"This journal is the definitive source for the most meaningful and critical information available on CNS drug targets and progress both in industrial and academic based neurodegeneration research."

Rudolf E. Tanzi
Harvard Medical School, USA

Forthcoming Special Issues

Current Perspective on Anti-Neurodegenerative Disorder’s Investigation: Computational Approaches to Clinical Research


Guest Editor(s): Anurag Khatkar
Tentative Publication Date: February, 2018
Submit Abstract via Email Download Description
Special Issues - In-Press

Brain Imaging and Automatic Analysis in Neurological and Psychiatric diseases


Guest Editor(s): Yu-Dong Zhang, Ti-Fei Yuan, Zheng-Chao Dong

Published Special Issues

Editorial Advisory Board Members Special Issue


Guest Editor(s): Stephen D. Skaper

Authors' Comments
I recommend CNS Neurological Disorders & Drug Targets to neuroscientists and practicing neurologists. The papers published on this platform are always of sufficient merit and quality. It maintains the highest standards of peer review, preserving the integrity of science

Abdelrahman Ibrahim Abushouk
(Faculty of Medicine, Ain Shams University, Cairo, Egypt)


CNS & Neurological Disorders - Drug Targets

,

Volume 17

-

Number 10



Review Article

Cariprazine in Bipolar Depression and Mania: State of the Art

, 17(10): 723 - 727

Marianna Mazza*, Giuseppe Marano, Gianandrea Traversi, Valentina Carocci, Benedetta Romano and Luigi Janiri


DOI: 10.2174/1871527317666180828120256




Review Article



Review Article

Neuroprotective Effects of Heat Shock Protein70

, 17(10): 736 - 742

Fatemeh Mohammadi , Navid Nezafat , Manica Negahdaripour , Fatemeh Dabbagh, Afshin Borhani Haghghi , Sedigheh Kianpour , Mehrzad Banihashemi and Younes Ghasemi *


DOI: 10.2174/1871527317666180827111152




Review Article

Cerebrospinal Fluid, Brain Electrolytes Balance, and the Unsuspected Intrinsic Property of Melanin to Dissociate the Water Molecule

, 17(10): 743 - 756

Arturo Solís Herrera, Ghulam Md Ashraf, María del Carmen Arias Esparza, Vadim V. Tarasov, Vladimir N. Chubarev, Marco F. Avila-Rodriguez, Alfiya Makhmutovа, Magdah Ganash, Osama F. Mosa, Abdul Hafeez, Sergey O. Bachurin and Gjumrakch Aliev*


DOI: 10.2174/1871527317666180904093430




Review Article



Research Article

Amyotrophic Lateral Sclerosis and Oxidative Stress: A Double-Blind Therapeutic Trial After Curcumin Supplementation

, 17(10): 767 - 779

Lucia Chico*, Elena Caldarazzo Ienco, Costanza Bisordi, Annalisa Lo Gerfo, Lucia Petrozzi, Antonio Petrucci, Michelangelo Mancuso and Gabriele Siciliano


DOI: 10.2174/1871527317666180720162029




Research Article

Clinical and Serological Biomarkers of Treatment’s Response in Multiple Sclerosis Patients Treated Continuously with Interferonβ-1b for More than a Decade

, 17(10): 780 - 792

Laura Iulia Bărcuţean, Andreea Romaniuc*, Smaranda Maier , Zoltan Bajko , Anca Moţăţăianu, Huţanu Adina, Iunius Simu, Sebastian Andone and Rodica Bălaşa


DOI: 10.2174/1871527317666180917095256




Acknowledgement   Open Access



Articles Ahead of Print


Cytarabine and Ferric Carboxymaltose (Fe+3) Increase Oxidative Damage and Alter Serotonergic Metabolism in Brain


David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortíz Herrera, Hugo Juárez Olguín*, Armando Valenzuela Peraza, Ernestina Hernández García, Francisca Trujillo Jiménez and Gerardo Barragán Mejí


View Abstract View on PubMed




Xuesaitong May Protect Against Ischemic Stroke by Modulating Microglial Phenotypes and Inhibiting Neuronal Cell Apoptosis via the STAT3 Signaling Pathway


Fangfang Li , Haiping Zhao, Ziping Han, Rongliang Wang, Zhen Tao, Zhibin Fan, Sijia Zhang, Guangwen Li, Zhigang Chen* and Yumin Luo*


View Abstract View on PubMed




Study of the Effects of L-tryptophane Nanoparticles on Motor Behavior in Alzheimer's Experimental Models


Andressa Leticia Miri*, Andressa Panegalli Hosni, Jossinelma Camargo Gomes, Rubiana Mara Mainardes, Najeh Maissar Khalil, Rossana Gabriela del Jesus Vásquez Marcano, Mário César da Silva Pereira and Ivo Ilvan Kerppers


View Abstract View on PubMed


Different Food Odors Control Brain Connectivity in Impulsive Children


Benito de Celis-Alonso, Silvia S. Hidalgo-Tobon, Eduardo Barragán-Pérez, Eduardo Castro-Sierra *, Pilar Dies-Suarez , Julio Garcia, Eduardo Moreno Barbosa and Oscar Arias-Carrión*


View Abstract View on PubMed


A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases


Jia Zhao*, Mengxia Zhu, Mukesh Kumar, Fung Yin Ngo, Yinghui Li, Lixing Lao and Jianhui Rong


View Abstract View on PubMed


Editor's Choice


Autophagy and Mitochondria: Targets in Neurodegenerative Disorders

, 2018; 17(9): 696 - 705

Ashutosh Kumar*, Amruta Dhawan, Alknanda Kadam and Akshada Shinde


DOI: 10.2174/1871527317666180816100203



Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

, 2018; 17(8): 626 - 639

Heidi Ormstad*, Vesna Bryn, Robert Verkerk, Ola H. Skjeldal, Bente Halvorsen, Ola Didrik Saugstad, Jorn Isaksen and Michael Maes


DOI: 10.2174/1871527317666180720163221



Light-Emitting Diode (LED) Therapy Attenuates Neurotoxicity of Methanol-Induced Memory Impairment and Apoptosis in The Hippocampus

, 2018; 17(7): 528 - 538

Amir Ghanbari, Kazem Zibara, Sepideh Salari, Majid Ghareghani, Parastou Rad, Wael Mohamed, Elham Ebadi, Mohamad Malekzadeh and Hamdallah Delaviz*


DOI: 10.2174/1871527317666180703111643



Protective Effect of Kaempferol on the Transgenic Drosophila Model of Alzheimer’s Disease

, 2018; 17(6): 421 - 429

Tanveer Beg, Smita Jyoti, Falaq Naz, Rahul, Fahad Ali, Syed Kashif Ali, Ahmed Mohamed Reyad and Yasir Hasan Siddique*


DOI: 10.2174/1871527317666180508123050



Pain-Related Behavior and Brain Activation in a Cynomolgus Macaque Model of Postoperative Pain

, 2018; 17(5): 348 - 360

Aldric Hama*, Takahiro Natsume, Shin`ya Ogawa, Yuji Awaga, Ikuo Hayashi, Akihisa Matsuda and Hiroyuki Takamatsu


DOI: 10.2174/1871527317666180515121350



Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke

, 2018; 17(4): 299 - 308

Bogdan Catalin, Otilia-Constantina Rogoveanu, Ionica Pirici, Tudor Adrian Balseanu, Adina Stan, Valerica Tudorica, Maria Balea, Ion Mindrila, Carmen Valeria Albu, Guleed Mohamed, Daniel Pirici* and Dafin Fior Muresanu


DOI: 10.2174/1871527317666180425124340




Inhibition of Neurogenesis by Zika Virus Infection

, 2018; 17(2): 78 - 86

Fahim Ahmad, Amna Siddiqui, Mohammad A. Kamal and Sayed Sartaj Sohrab*


DOI: 10.2174/1871527317666180202115114




Open Access Articles

Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic Plasticity

, 2018; 17(5): 389 - 399

Kai Wang, Weiming Sun, Linlin Zhang, Wei Guo, Jiachun Xu, Shuang Liu, Zhen Zhou and Yulian Zhang*




Physiological and Morphological Principles Underpinning Recruitment of the Cerebellar Reserve

, 2018; 17(3): 184 - 192

Shinji Kakei*, Takahiro Ishikawa, Jongho Lee, Takeru Honda and Donna S. Hoffman




The Role of Innate Immune System Receptors in Epilepsy Research

, 2017; 16(7): 749 - 762

Jessica Cordero-Arreola, Rachel M. West, Julieta Mendoza-Torreblanca, Edna Mendez-Hernandez, Jose Salas-Pacheco, Manuel Menendez-Gonzalez, Rafael C. Freire, Sergio Machado, Eric Murillo-Rodriguez, Antonio E. Nardi and Oscar Arias-Carrion*




Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate

, 2017; 16(6): 714 - 723

Josephine D`Alessandro, Kevin Garofalo, Ganlin Zhao, Christopher Honan, Jay Duffner, Ishan Capila, Ian Fier, Ganesh Kaundinya, Daniel Kantor and Tanmoy Ganguly*




Nanomaterials for Neurology: State-of-the-Art

, 2016; 15(10): 1306 - 1324

María Fernanda Veloz-Castillo, Rachel M. West, Jessica Cordero-Arreola, Oscar Arias-Carrión and Miguel A. Méndez-Rojas




Functions of Ghrelin in Brain, Gut and Liver

, 2016; 15(8): 956 - 963

Cristina Stasi and Stefano Milani





The Potential of Nasal Oxytocin Administration for Remediation of Autism Spectrum Disorders

, 2016; 15(5): 564 - 577

Yuko Okamoto, Makoto Ishitobi, Yuji Wada and Hirotaka Kosaka





The Effects of Testosterone Supplementation on Cognitive Functioning in Older Men.

, 2016; 15(3): 337 - 343

Eka J. Wahjoepramono, Prita R. Asih, Vilia Aniwiyanti, Kevin Taddei, Satvinder S. Dhaliwal, Stephanie J. Fuller, Jonathan Foster, Malcolm Carruthers, Giuseppe Verdile, Hamid R Sohrabi and Ralph N. Martins




Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid

, 2015; 14(10): 1343 - 1349

Evgeny E. Akkuratov, Jian Wu, David Sowa, Zahoor A. Shah and Lijun Liu






The Role of Neuroimaging in Our Understanding of the Suicidal Brain

, 2013; 12(7): 921 - 929

Stefanie Desmyter, Stijn Bijttebier and Kees van Heeringen






Most Cited Articles

Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System

, 2016; 15(3): 329-336.

Jerzy Leszek, George E. Barreto, Kazimierz Gąsiorowski, Euphrosyni Koutsouraki, Marco Ávila-Rodrigues and Gjumrakch Aliev


DOI: 10.2174/1871527315666160202125914


Recent updates on the dynamic association between oxidative stress and neurodegenerative disorders

, 2016; 15(3): 310-320.

Taqi A. Khan, Iftekhar Hassan, Ausaf Ahmad, Asma Perveen, Shazia Aman, Saima Quddusi, Ibrahim M. Alhazza, Ghulam M. Ashraf and Gjumrakch Aliev


DOI: 10.2174/1871527315666160202124518



Novel Therapeutic Strategies for Dementia

, 2016; 15(2): 141-241.

Ramón Cacabelos, Clara Torrellas, Iván Carrera, Pablo Cacabelos, Lola Corzo, Lucía Fernández-Novoa, Iván Tellado, Juan C. Carril and Gjumrakch Aliev


DOI: 10.2174/1871527315666160202121548


Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease

, 2016; 15(3): 292-300.

Juan C. Jurado-Coronel, Marco Ávila-Rodriguez, Valentina Echeverria, Oscar Alejandro Hidalgo, Janneth Gonzalez, Gjumrakch Aliev and George E. Barreto


DOI: 10.2174/1871527315666160202125519



Nanowired Drug Delivery Across the Blood-Brain Barrier in Central Nervous System Injury and Repair

, 2016; 15(9): 1092-1117.

Aruna Sharma, Preeti Menon, Dafin F. Muresanu, Asya Ozkizilcik, Z. Ryan Tian, José V. Lafuente and Hari S. Sharma


DOI: 10.2174/1871527315666160819123059


Coenzyme Q10 for Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis

, 2016; 15(1): 45-53.

Ahmed Negida, Ahmed Menshawy, Gehad El Ashal, Yasmin Elfouly, Yasmein Hani, Yasmin Hegazy, Samar El ghonimy, Samar Fouda and Yomna Rashad


DOI: 10.2174/1871527314666150821103306


A comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder.

, 2016; 15(1): 35-44.

Domenico De Berardis, Laura Orsolini, Nicola Serroni, Gabriella Girinelli, Felice Iasevoli, Carmine Tomasetti, Andrea de Bartolomeis, Monica Mazza, Alessandro Valchera, Michele Fornaro, Giampaolo Perna, Monica Piersanti, Marco Di Nicola, Marilde Cavuto, Giovanni Martinotti and Massimo Di Giannantonio


DOI: 10.2174/1871527314666150821103825


Alzheimer’s Disease Detection by Pseudo Zernike Moment and Linear Regression Classification

, 2017; 16(1): 11-15.

Shui-Hua Wang, Sidan Du, Yin Zhang, Preetha Phillips, Le-Nan Wu, Xian-Qing Chen and Yu-Dong Zhang


DOI: 10.2174/1871527315666161111123024



Most Accessed Articles

The Efficacy and Safety of Pharmacological Treatments for Post-stroke Aphasia

, 2018; 17(7): 509-521.

Xiaoyan Zhang, Bohui Shu, Dongdong Zhang, Lina Huang, Qizhi Fu and Ganqin Du*


DOI: 10.2174/1871527317666180706143051



Effects of Exercise on Anxiety and Depression Disorders: Review of Meta- Analyses and Neurobiological Mechanisms

, 2014; 13(6): 1002-1014.

Mirko Wegner, Ingo Helmich, Sergio Machado, Antonio E. Nardi, Oscar Arias-Carrion and Henning Budde


DOI: 10.2174/1871527313666140612102841


In Silico Analyses for Key Genes and Molecular Genetic Mechanism in Epilepsy and Alzheimer’s Disease

, 2018; 17(8): 608-617.

Xiao-wen Jiang, Hong-yuan Lu, Ziru Xu, Tian-yi Liu, Qiong Wu, Yue Yang, Qing-chun Zhao* and Hui-yuan Gao*


DOI: 10.2174/1871527317666180724150839


Anxiety: A Systematic Review of Neurobiology, Traditional Pharmaceuticals and Novel Alternatives from Medicinal Plants

, 2014; 13(1): 150-165.

Erica Aparecida Gelfuso, Daiane Santos Rosa, Ana Lúcia Fachin, Márcia Renata Mortari, Alexandra Olimpio Siqueira Cunha and Rene Oliveira Beleboni


DOI: 10.2174/18715273113129990102


C-Abl Inhibition; A Novel Therapeutic Target for Parkinson's Disease

, 2018; 17(1): 14-21.

Abdelrahman Ibrahim Abushouk, Ahmed Negida*, Rasha Abdelsalam Elshenawy, Hossam Zein, Ali M. Hammad, Ahmed Menshawy and Wael M.Y. Mohamed


DOI: 10.2174/1871527316666170602101538


Vitamin D’s Molecular Action Mechanism in Attention-Deficit/ Hyperactivity Disorder: A Review of Evidence

, 2018; 17(4): 280-290.

Ahmad Saedisomeolia, Mahsa Samadi, Fatemeh Gholami, Marzieh Seyedi, Mohammad Effatpanah, Rezvan Hashemi, Mina Abdolahi and Niyaz Mohammadzadeh Honarvar*


DOI: 10.2174/1871527317666180501111627



Cariprazine in Bipolar Depression and Mania: State of the Art

, 2018; 17(10): 723-727.

Marianna Mazza*, Giuseppe Marano, Gianandrea Traversi, Valentina Carocci, Benedetta Romano and Luigi Janiri


DOI: 10.2174/1871527317666180828120256



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