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Central Nervous System Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Central Nervous System Agents

Volume 20, 3 Issues, 2020
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access
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In the current Pandemic scenario, all articles related to Coronavirus will be processed on a quick track basis, to ensure timely review and publication of much needed research

Aims & Scope

Central Nervous System Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new central nervous system agents.

Containing a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics, Central Nervous System Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in the field.

Central Nervous System Agents in Medicinal Chemistry

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Volume 20

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Number 1



Biography   Open Access



Preface   Open Access



Research Article   Open Access



Research Article

An Evaluation of the Effects of Pyridoxal Phosphate in Chlorpromazineinduced Parkinsonism using Mice

, 20(1): 13 - 25

Anthony T. Olofinnade, Tolulope M. Onaolapo, Samad Oladimeji, Adetunji M. Fatoki, Covenant I. Balogun, Adejoke Y. Onaolapo* and Olakunle J. Onaolapo


DOI: 10.2174/1871524920666200120142508


Research Article



Research Article



Research Article   Open Access



Research Article   Open Access



Articles Ahead of Print

Drug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with Plasmodium berghei


Akeem Ayankunle*, Olayemi Wakeel, Oyetunji Kolawole, Adesola Oyekale, Olusola Ojurongbe and Oluwaseyi Adeyeba


DOI: 10.2174/1871524920666200604151907
View Abstract View on PubMed




Theoretical Study of Monoamine Oxidase B Inhibitors as Drug Candidates for Treatment of Parkinson’s Disease


Lucilene R. Souza, Leide C. S. Picanço, Maiara F. B. Brito, Marcos R. S. Almeida, Bianca L. B. Marino, Kessia P. A. Sousa, Jaderson V. Ferreira, Cleydson B. S. Rodrigues, Guilherme M. Silva, Carlos H. T. P. Silva, Carlton A. Taft and Lorane I. S. Hage-Melim*


DOI: 10.2174/1871524920666200217110211
View Abstract View on PubMed




Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice


Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75 - 99

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855



A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis

, 2019; 19(1): 8 - 14

Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*


DOI: 10.2174/1871524918666181017152053



Classification (Agonist/Antagonist) and Regression “Structure-Activity” Models of Drug Interaction with 5-HT6

, 2018; 18(3): 213 - 221

Oleg A. Raevsky, Veniamin Y. Grigorev, Alexander V. Yarkov, Daniel E. Polianczyk, Vadim V. Tarasov, Elena V. Bovina, Elena N. Bryzhakina, John C. Dearden, Marco Avila-Rodriguez and Gjumrakch Aliev*


DOI: 10.2174/1871524918666180827100437




Astrocyte´s RAGE: More Than Just a Question of Mood

, 2018; 18(1): 39 - 48

Rodrigo E. Gonzalez-Reyes* and Maria G. Rubiano


DOI: 10.2174/1871524916999160505105121





Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene

, 2017; 17(1): 51 - 57

Bijo Mathew, Githa E. Mathew, Jerad Suresh, Mohammed Jaseel, D. Usman, P. N. Shiva Subramanyan, Kallivalappil F. Safna and Jobin K. Vilapurathu


DOI: 10.2174/1871524915999151028111728




Open Access Articles




The Role of Melanin to Dissociate Oxygen from Water to Treat Retinopathy of Prematurity

, 2019; 19(3): 215 - 222

Arturo S. Herrera, María del Carmen A. Esparza, Paola E.S. Arias, Ghulam M. Ashraf, Osama F. Mosa, Vladimir P. Fisenko, Susanna S. Sologova, Samira A. Dostdar, Alexander V. Sokolov, Elena V. Bovina, Vladimir N. Chubarev, Vadim V. Tarasov, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*




A Novel Highly Selective Cannabinoid CB2 Agonist Reduces in vitro Growth and TGF-beta Release of Human Glial Cell Tumors

, 2019; 19(3): 206 - 214

Chiara Cioni, Maristella Tassi, Giuseppe Marotta, Claudia Mugnaini, Federico Corelli* and Pasquale Annunziata*





Noradrenergic Regulation of Hippocampus-Dependent Memory

, 2019; 19(3): 187 - 196

Peter V. Nguyen and Steven A. Connor*




Berberine: A Plant-derived Alkaloid with Therapeutic Potential to Combat Alzheimer’s disease

, 2019; 19(3): 154 - 170

Anurag K. Singh, Santosh K. Singh, Manmath K. Nandi, Gaurav Mishra, Anand Maurya, Arati Rai, Gopal K. Rai, Rajendra Awasthi*, Bhupesh Sharma and Giriraj T. Kulkarni




Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75 - 99

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*








Opening New Scenarios for Human MAO Inhibitors

, 2016; 16(2): 98 - 104

Celeste De Monte, Melissa D'Ascenzio, Paolo Guglielmi, Veronica Mancini and Simone Carradori






Most Cited Articles




Letter

Cholinesterase inhibitory activities of selected halogenated thiophene chalcones

, 2019; 19(1): 67-71.

Della G.T. Parambi, Fakhrya Aljoufi, Vikneswaran Murugaiyah, Githa E. Mathew, Sanal Dev, Balasubramanain Lakshminarayanan, Omnia M. Hendawy and Bijo Mathew*


DOI: 10.2174/1871524918666181119114016


Research Article

A novel highly selective cannabinoid CB2 agonist reduces in vitro growth and TGF-beta release of human glial cell tumors

, 2019; 19(3): 206-214.

Chiara Cioni, Maristella Tassi, Giuseppe Marotta, Claudia Mugnaini, Federico Corelli* and Pasquale Annunziata*


DOI: 10.2174/1871524919666190923154351



Review Article

Acrylamide induced toxicity and the propensity of phytochemicals in amelioration: A review

, 2019; 19(2): 100-113.

Shinomol George Kunnel*, Sunitha Subramanya, Pankaj Satapathy, Ishtapran Sahoo and Farhan Zameer*


DOI: 10.2174/1871524919666190207160236


Review Article

Antioxidant effect of flavonoids present in euterpe oleracea martius and neurodegenerative diseases: A literature review

, 2019; 19(2): 75-99.

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855




Review Article

Berberine: A plant-derived alkaloid with therapeutic potential to combat Alzheimer’s disease

, 2019; 19(3): 154-170.

Anurag K. Singh, Santosh K. Singh, Manmath K. Nandi, Gaurav Mishra, Anand Maurya, Arati Rai, Gopal K. Rai, Rajendra Awasthi*, Bhupesh Sharma and Giriraj T. Kulkarni


DOI: 10.2174/1871524919666190820160053





Research Article

An evaluation of the effects of pyridoxal phosphate in chlorpromazineinduced parkinsonism using mice

, 2020; 20(1): 13-25.

Anthony T. Olofinnade, Tolulope M. Onaolapo, Samad Oladimeji, Adetunji M. Fatoki, Covenant I. Balogun, Adejoke Y. Onaolapo* and Olakunle J. Onaolapo


DOI: 10.2174/1871524920666200120142508



Most Accessed Articles

Basic Sleep Mechanisms: An Integrative Review

, 2012; 12(1): 38-54.

Eric Murillo-Rodriguez, Oscar Arias-Carrion, Abraham Zavala-Garcia, Andrea Sarro-Ramirez, Salvador Huitron-Resendiz and Gloria Arankowsky-Sandoval


DOI: 10.2174/187152412800229107


A Novel Highly Selective Cannabinoid CB2 Agonist Reduces in vitro Growth and TGF-beta Release of Human Glial Cell Tumors

, 2019; 19(3): 206-214.

Chiara Cioni, Maristella Tassi, Giuseppe Marotta, Claudia Mugnaini, Federico Corelli* and Pasquale Annunziata*


DOI: 10.2174/1871524919666190923154351





Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75-99.

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855


Crude Venom from Nematocysts of the Jellyfish Pelagia noctiluca as a Tool to Study Cell Physiology

, 2015; 15(2): 68-73.

Rossana Morabito, Giuseppina L. Spada, Rosalia Crupi, Emanuela Esposito and Angela Marino


DOI: 10.2174/1871524914666141028150212



Sex Hormones and Brain Dopamine Functions

, 2014; 14(2): 62-71.

Ramon Sotomayor-Zarate, Gonzalo Cruz, Georgina M. Renard, Pedro Espinosa and Victor D. Ramirez


DOI: 10.2174/1871524914666141226105137


Biomarkers of Cell Damage Induced by Oxidative Stress in Parkinsons Disease and Related Models

, 2010; 10(4): 278-286.

Julio Cesar Tobon-Velasco, Liliana Carmona-Aparicio, Syed F. Ali and Abel Santamaria


DOI: 10.2174/187152410793429719



Co-Editors

G. Aliev
"GALLY" International Biomedical Research Consulting LLC
San Antonio, TX
(USA)
Biography View Full Editorial Board
G.S. Hamilton
Biopharma Research Leader, Organic and Medical Chemist, Registered US Patent Agent
Catonsville, MD
(USA)
Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry - Central Nervous System Agents was launched in 2001 and later renamed in 2006 as Central Nervous System Agents in Medicinal Chemistry.
Scopus CiteScore Metrics: 1.34

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