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Central Nervous System Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Central Nervous System Agents

Volume 21, 3 Issues, 2021
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Central Nervous System Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new central nervous system agents.

Containing a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics, Central Nervous System Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in the field.

Central Nervous System Agents in Medicinal Chemistry

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Volume 20

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Number 3



Biography   Open Access



Review Article

Old Drugs with New Tricks: Paradigm in Drug Development Pipeline for Alzheimer’s Disease

, 20(3): 157 - 176

Tanay Dalvi, Bhaskar Dewangan, Rudradip Das, Jyoti Rani, Suchita D. Shinde, Nazmina Vhora, Alok Jain and Bichismita Sahu*


DOI: 10.2174/1871524920666201021164805


Research Article



Research Article

Extraction, GC-MS Evaluation and Anti-epileptic Potential of Seeds Ethanolic Extract of Putranjiva roxburghii Wall

, 20(3): 186 - 193

Chandra Kala*, Syed S. Imam, Mohamad Taleuzzaman, Sadaf J. Gilani, Syed S. Ali, Iqra Rahat, Adil Ahmad and Najam A. Khan


DOI: 10.2174/1871524920999201027125743


Research Article

Anti-nociceptive Effect of Euphorbia hirta Leaf Extract: Involvement of Adenosine, Cholinergic, and Opioid Receptors

, 20(3): 194 - 205

Temitope Janet Olatoyan-Layonu, Olayemi Kamoru Wakeel*, Abraham Ifedayo Abe, Olusola Ojurongbe and Oluwaseyi Adegboyega Adeyeba


DOI: 10.2174/1871524920666200705221956


Research Article



Case Report

The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report

, 20(3): 218 - 225

Arturo S. Herrera, Narasimha M. Beeraka, Luis Fernando T. Solis, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1871524920666201109152951


Acknowledgement   Open Access



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice



Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75 - 99

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855



A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis

, 2019; 19(1): 8 - 14

Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*


DOI: 10.2174/1871524918666181017152053



Classification (Agonist/Antagonist) and Regression “Structure-Activity” Models of Drug Interaction with 5-HT6

, 2018; 18(3): 213 - 221

Oleg A. Raevsky, Veniamin Y. Grigorev, Alexander V. Yarkov, Daniel E. Polianczyk, Vadim V. Tarasov, Elena V. Bovina, Elena N. Bryzhakina, John C. Dearden, Marco Avila-Rodriguez and Gjumrakch Aliev*


DOI: 10.2174/1871524918666180827100437




Astrocyte`s RAGE: More Than Just a Question of Mood

, 2018; 18(1): 39 - 48

Rodrigo E. Gonzalez-Reyes* and Maria G. Rubiano


DOI: 10.2174/1871524916999160505105121





Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene

, 2017; 17(1): 51 - 57

Bijo Mathew, Githa E. Mathew, Jerad Suresh, Mohammed Jaseel, D. Usman, P. N. Shiva Subramanyan, Kallivalappil F. Safna and Jobin K. Vilapurathu


DOI: 10.2174/1871524915999151028111728



Open Access Articles




The Role of Melanin to Dissociate Oxygen from Water to Treat Retinopathy of Prematurity

, 2019; 19(3): 215 - 222

Arturo S. Herrera, María del Carmen A. Esparza, Paola E.S. Arias, Ghulam M. Ashraf, Osama F. Mosa, Vladimir P. Fisenko, Susanna S. Sologova, Samira A. Dostdar, Alexander V. Sokolov, Elena V. Bovina, Vladimir N. Chubarev, Vadim V. Tarasov, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*




A Novel Highly Selective Cannabinoid CB2 Agonist Reduces in vitro Growth and TGF-beta Release of Human Glial Cell Tumors

, 2019; 19(3): 206 - 214

Chiara Cioni, Maristella Tassi, Giuseppe Marotta, Claudia Mugnaini, Federico Corelli* and Pasquale Annunziata*





Noradrenergic Regulation of Hippocampus-Dependent Memory

, 2019; 19(3): 187 - 196

Peter V. Nguyen and Steven A. Connor*




Berberine: A Plant-derived Alkaloid with Therapeutic Potential to Combat Alzheimer’s disease

, 2019; 19(3): 154 - 170

Anurag K. Singh, Santosh K. Singh, Manmath K. Nandi, Gaurav Mishra, Anand Maurya, Arati Rai, Gopal K. Rai, Rajendra Awasthi*, Bhupesh Sharma and Giriraj T. Kulkarni




Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75 - 99

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*








Opening New Scenarios for Human MAO Inhibitors

, 2016; 16(2): 98 - 104

Celeste De Monte, Melissa D'Ascenzio, Paolo Guglielmi, Veronica Mancini and Simone Carradori






Most Cited Articles




Review Article (Mini-Review)

Understanding the pathogenesis involved in parkinson’s disease and potential therapeutic treatment strategies

, 2020; 20(2): 88-102.

Meenakshi Dhanawat, Dinesh K. Mehta, Sumeet Gupta and Rina Das*


DOI: 10.2174/1871524920666200705222842



Research Article

Drug repositioning: Antimalarial activities of gaba analogs in mice infected with plasmodium berghei

, 2020; 20(2): 110-121.

Akeem A. Ayankunle*, Olayemi K. Wakeel, Oyetunji T. Kolawole, Adesola O. Oyekale, Olusola Ojurongbe and Oluwaseyi A. Adeyeba


DOI: 10.2174/1871524920666200604151907


Research Article

Theoretical study of monoamine oxidase b inhibitors as drug candidates for treatment of parkinson’s disease

, 2020; 20(2): 128-143.

Lucilene R. Souza, Leide C.S. Picanço, Maiara F.B. Brito, Marcos R.S. Almeida, Bianca L.B. Marino, Kessia P.A. Sousa, Jaderson V. Ferreira, Cleydson B.R. dos Santos, Guilherme M. Silva, Carlos H.T.P. Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1871524920666200217110211


Research Article

Potential mechanisms involved in the anticonvulsant effect of methanol extract of pyrenancantha staudtii in mice

, 2020; 20(2): 144-154.

Olayemi K. Wakeel*, Oluropo B. Awosan, Oyetunji T. Kolawole, Akeem A. Ayankunle, Olukunle J. Onaolapo and Oluwaseyi A. Adeyeba


DOI: 10.2174/1871524920666200211113633



Research Article

An evaluation of the effects of pyridoxal phosphate in chlorpromazineinduced parkinsonism using mice

, 2020; 20(1): 13-25.

Anthony T. Olofinnade, Tolulope M. Onaolapo, Samad Oladimeji, Adetunji M. Fatoki, Covenant I. Balogun, Adejoke Y. Onaolapo* and Olakunle J. Onaolapo


DOI: 10.2174/1871524920666200120142508



Research Article

Electronegativity in substituted-4(H)-quinazolinones causes anxiolysis without a sedative-hypnotic adverse reaction in female wistar rats

, 2020; 20(1): 26-40.

Shweta Mishra, Debashree Das, Adarsh Sahu, Ekta Verma, Shailendra Patil, Ram Kishore Agarwal and Asmita Gajbhiye*


DOI: 10.2174/1871524920666191220112545



Preface

Preface

, 2020; 20(1): 2-2.

G. Aliev


DOI: 10.2174/187152492001200303165133



Most Accessed Articles




Drug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with Plasmodium berghei

, 2020; 20(2): 110-121.

Akeem A. Ayankunle*, Olayemi K. Wakeel, Oyetunji T. Kolawole, Adesola O. Oyekale, Olusola Ojurongbe and Oluwaseyi A. Adeyeba


DOI: 10.2174/1871524920666200604151907



Potential Mechanisms Involved in the Anticonvulsant Effect of Methanol Extract of Pyrenancantha staudtii in Mice

, 2020; 20(2): 144-154.

Olayemi K. Wakeel*, Oluropo B. Awosan, Oyetunji T. Kolawole, Akeem A. Ayankunle, Olukunle J. Onaolapo and Oluwaseyi A. Adeyeba


DOI: 10.2174/1871524920666200211113633



Theoretical Study of Monoamine Oxidase B Inhibitors as Drug Candidates for Treatment of Parkinson’s Disease

, 2020; 20(2): 128-143.

Lucilene R. Souza, Leide C.S. Picanço, Maiara F.B. Brito, Marcos R.S. Almeida, Bianca L.B. Marino, Kessia P.A. Sousa, Jaderson V. Ferreira, Cleydson B.R. dos Santos, Guilherme M. Silva, Carlos H.T.P. Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1871524920666200217110211


Anti-nociceptive Effect of Euphorbia hirta Leaf Extract: Involvement of Adenosine, Cholinergic, and Opioid Receptors

, 2020; 20(3): 194-205.

Temitope Janet Olatoyan-Layonu, Olayemi Kamoru Wakeel*, Abraham Ifedayo Abe, Olusola Ojurongbe and Oluwaseyi Adegboyega Adeyeba


DOI: 10.2174/1871524920666200705221956


Old Drugs with New Tricks: Paradigm in Drug Development Pipeline for Alzheimer’s Disease

, 2020; 20(3): 157-176.

Tanay Dalvi, Bhaskar Dewangan, Rudradip Das, Jyoti Rani, Suchita D. Shinde, Nazmina Vhora, Alok Jain and Bichismita Sahu*


DOI: 10.2174/1871524920666201021164805




The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report

, 2020; 20(3): 218-225.

Arturo S. Herrera, Narasimha M. Beeraka, Luis Fernando T. Solis, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1871524920666201109152951





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