Cancer cells show excessive need of nutrients and energy. Not only this, activated lymphocytes, in particular the T lymphocytes and myeloid derived cells also show differential expression in the metabolic pathway genes in tumor microenvironment. Therefore, understanding the metabolic changes in the context of cancer development will help to identify new therapeutic targets to treat cancer.
Keywords: Arginine metabolism, Autophagy pathway, Immune-metabolism, Immune-suppressors, Leptin, Reactive oxygen species, Tumor metabolism.
About this chapter
Cite this chapter as:Mahbuba Rahman ;
Cancer Metabolism: A Perspective on the Involvement of the Immune System and Metabolic Pathways in Cancer Development, Frontiers in Cancer Immunology Systems Biology in Cancer Immunotherapy (2016) 2: 42. https://doi.org/10.2174/9781681083070116020004
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