Sometimes genomic and transcriptomic information of single cells, instead
of those produced from cell populations, are desired. Obtaining such information relies
on single cell sequencing (SCS) and single cell transcriptome (SCT) sequencing.
Although SCT sequencing is in fact part of SCS, they are readily distinguishable not
only in research objective, but also in experimental procedure and bioinformatic
approach. We will first review the history and achievements that have been made in
these fields, and then discuss an experimental procedure of SCT sequencing to gain
more insight into the subject.
Keywords: SCS, Single cell Sequencing, Single cell transcriptome sequencing, SCT,
Transcriptome.
