Abstract
Uncontrolled cell division resulting in cancer is a significant contributor to
mortality rates, with breast cancer being the most common form affecting women.
When the disease progresses, the uncontrolled cell division can spread through the
bloodstream to other parts of the body, making treatment through chemotherapy and
radiation therapy challenging. As such, there is an urgent need for the discovery of new
drugs and targets to combat this disease. This chapter delves into the physiological role
of insulin and hypoxia in breast cancer cell invasion and metastasis, which can
potentially increase the druggability of the pathway. It is a valuable resource for those
researching new druggable targets in these pathways.
Keywords: Breast cancer, Cell invasion and migration, Correlation, Hypoxia, Insulin.
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