Microsurgery In Liver Research

Portal Surgery: Portosystemic Shunts and Portal Hypertension

Author(s): Maria-Angeles Aller, Marta Mendez, Maria-Paz Nava, Laudino Lopez, Diana Curras, Ana de Paz, Jorge-Luis Arias and Jaime Arias

Pp: 117-136 (20)

DOI: 10.2174/978160805068010901010117

* (Excluding Mailing and Handling)


The most frequently used experimental models for portal microsurgery are those achieved through portal systemic shunts and partial portal vein ligation. Portacaval shunts are appropriate techniques for microsurgical training but also for researching chronic hepatic insufficiency and particularly hepatic encephalopathy. Portal hypertension by triple partial portal vein ligation, is associated with a low-grade inflammatory response at the splanchnic (enteropathy and liver steatosis) and systemic levels.

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