Nanobiotechnology: Principles and Applications

The Roles of Nanoparticles in Ovarian Cancer Treatment and Diagnosis

Author(s): Bitupon Gogoi, Devendra Jain, Madan Mohan Sharma, Rajeev Mishra* and Abhijeet Singh *

Pp: 1-10 (10)

DOI: 10.2174/9789815123555123010004

* (Excluding Mailing and Handling)


Ovarian cancer, an aggressive epithelial cancer, remains a major cause of cancer mortality worldwide among women, but it can be diagnosed at an early stage also. Surgical removal of ovarian tumour is a good option for the initial treatment, but this is suitable only at the early stage of cancer. Surgery and other therapies like chemotherapy, hormone role therapy and immunotherapy alone are insufficient for the treatment of today’s advanced ovarian cancer. The aim of this book chapter is to review the use of nano-particles in the treatment of ovarian cancer, along with surgery. It is believed that nano therapies have lots of advantages like they stabilize drugs in our body, deliver and penetrate the drugs to tumour-specific cells and can profile the toxicity of chemotherapy. This book chapter also covers the development of nanotherapies, types of nanocarriers and their role in ovarian cancer diagnosis and treatment.

Keywords: Apoptosis, Biomarker, Chemotherapy, Detoxification, Drug cargo, DNA repair, Drug resistance, Graft rejection, Gynaecological cancer, Heterogeneous nature, Hydrophilic corona, Intracellular delivery, M alignancy, Metastatic tumour, Nanocarriers, Nanomaterial, Nanotechnology, Nano transmitter, Photodynamic therapy, Prophylactic, Photo thermal therapy, Renal clearance, Silent Killer, Systematic toxicity.

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