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Medical Applications of Beta-Glucan

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Introduction To β-glucans

Author(s): Betül Gürünlü

Pp: 1-18 (18)

DOI: 10.2174/9789815039238122010003

* (Excluding Mailing and Handling)

Abstract

Generally, β -glucan is a chemical name of a polymer of β -glucose. The
therapeutic effect of β-glucans (beta-glucan) has long been known. Mushrooms
are sacred food in ancient Egypt and used for prolonging life three thousand years
ago. The medicinal usage of mushrooms that are a major source for β-glucans
were mentioned in the texts in India dating back 500 years [1]. US Food and Drug
Administration (FDA) recommends an intake of 3 g/day of β-glucan as
cholesterol-reducing foodstuffs in 1997 [2]. American Diabetes Association
(ADA) pointed that main aim should be kept the LDL-cholesterol (LDL-C) level
less than 2.6 mmol/l (100 mg/dl) in individuals without overt cardiovascular
disease (CVD). It also has a strong anti-oxidative property which helps in
overcoming the problem of oxidative stress of the human body. β-glucan also
reduces the chronic fatique syndrome and inhibits the cancer development....

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