Cardiovascular diseases are the main cause of death worldwide and therefore, the most important public health problem. Many factors play a role in the development of cardiovascular diseases, among others: obesity, hypertension, diabetes mellitus, hyperlipidemia, inadequate diet, sedentary life and smoking. Cardiovascular disease incidence can be improved increasing the intake of fruits and vegetables. Cohort studies and randomized controlled trials have shown that intake of dietary antioxidants (vitamins E, A, C, and poliphenols), antioxidant supplements or dietary patterns (Mediterranean diet) influence differently in the occurrence of cardiovascular events or death. This review examines relevant clinical reports on dietary compounds, supplements or dietary patterns to analyze what kind of patients (if any) with increased cardiovascular risk factors will get any benefit for these therapeutic options.
Keywords: Antioxidant dietary supplements, Antioxidant intake, Cardiovascular disease, Carotenoids, Cohort studies, Coronary heart disease, Evidence, Flavonoids, Mediterranean diet, Mortality, Poliphenols, Prevention, Randomized controlled trials, Stroke, Vitamin A, Vitamin C, Vitamin E.