Cardiovascular diseases are the main cause of death worldwide and
therefore, the most important public health problem. Many factors play a role in the
development of cardiovascular diseases, among others: obesity, hypertension, diabetes
mellitus, hyperlipidemia, inadequate diet, sedentary life and smoking. Cardiovascular
disease incidence can be improved increasing the intake of fruits and vegetables.
Cohort studies and randomized controlled trials have shown that intake of dietary
antioxidants (vitamins E, A, C, and poliphenols), antioxidant supplements or dietary
patterns (Mediterranean diet) influence differently in the occurrence of cardiovascular
events or death. This review examines relevant clinical reports on dietary compounds,
supplements or dietary patterns to analyze what kind of patients (if any) with increased
cardiovascular risk factors will get any benefit for these therapeutic options.
Keywords: Antioxidant dietary supplements, Antioxidant intake, Cardiovascular
disease, Carotenoids, Cohort studies, Coronary heart disease, Evidence,
Flavonoids, Mediterranean diet, Mortality, Poliphenols, Prevention, Randomized
controlled trials, Stroke, Vitamin A, Vitamin C, Vitamin E.
