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Review Article

BRAF在甲状腺乳头状微癌中的地位:简要回顾

卷 19, 期 9, 2019

页: [665 - 672] 页: 8

弟呕挨: 10.2174/1566524019666190717161359

价格: $65

Open Access Journals Promotions 2
摘要

甲状腺乳头状癌（PTMC）被世界卫生组织定义为直径10毫米或更小的乳头状癌。 通常，尽管少数PTMC具有侵袭性病程，但PTMC表现出缓慢的临床行为并具有良好的预后。 然而，在手术后确定PTMC侵袭性亚型的努力尚无定论。 在甲状腺癌中已经确定了几种致癌途径，并将其翻译用于改善预后和临床管理。 特别是，BRAFV600E突变在大型，侵袭性，复发和晚期肿瘤中更常见。 我们旨在审查有关BRAFV600E突变作为PTMC预后因素的研究。

关键词: 甲状腺乳头状微癌，癌症，预后，BRAF，突变。

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