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General Review Article

珊瑚来源的微生物的化学和生物活性海洋天然产物（2015-2017）

卷 26, 期 38, 2019

页: [6930 - 6941] 页: 12

弟呕挨: 10.2174/0929867326666190626153819

价格: $65

摘要

珊瑚来源的微生物以其产生具有药物重要性的新产品的固有能力而闻名。 到2014年，已从珊瑚来源的微生物中分离出近260种海洋天然产物（MNP）。在过去三年中，从珊瑚相关的微生物中分离出118种MNP，包括46种新化合物，两种具有新颖骨架的化合物和四种新型天然物质。 产品。 它们中的大多数表现出针对肿瘤细胞系，寄生虫，病原细菌，真菌和病毒的体外或体内活性。 我们回顾了2015年至2017年报告的天然产物，它们具有针对不同生物学目标的广泛生物活性。

关键词: 珊瑚来源的微生物，海洋天然产物，生物活性，药物潜力，寄生虫，致病菌。

« Previous Next »
[1]
Abdelmohsen, U.R.; Balasubramanian, S.; Oelschlaeger, T.A.; Grkovic, T.; Pham, N.B.; Quinn, R.J.; Hentschel, U. Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections. Lancet Infect. Dis., 2017, 17(2), e30-e41.
[http://dx.doi.org/10.1016/S1473-3099(16)30323-1] [PMID: 27979695]
[2]
Blunt, J.W.; Carroll, A.R.; Copp, B.R.; Davis, R.A.; Keyzers, R.A.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2018, 35(1), 8-53.
[http://dx.doi.org/10.1039/C7NP00052A] [PMID: 29335692]
[3]
Hou, X.M.; Xu, R.F.; Gu, Y.C.; Wang, C.Y.; Shao, C.L. Biological and chemical diversity of coral-derived microorganisms. Curr. Med. Chem., 2015, 22(32), 3707-3762.
[http://dx.doi.org/10.2174/0929867322666151006093755] [PMID: 26438250]
[4]
Kellogg, C.A.; Ross, S.W.; Brooke, S.D. Bacterial community diversity of the deep-sea octocoral Paramuricea placomus. PeerJ, 2016, 4e2529
[http://dx.doi.org/10.7717/peerj.2529] [PMID: 27703865]
[5]
Pham, T.M.; Wiese, J.; Wenzel-Storjohann, A.; Imhoff, J.F. Diversity and antimicrobial potential of bacterial isolates associated with the soft coral Alcyonium digitatum from the Baltic Sea. Antonie van Leeuwenhoek, 2016, 109(1), 105-119.
[http://dx.doi.org/10.1007/s10482-015-0613-1] [PMID: 26558794]
[6]
Zhang, Y.Y.; Ling, J.; Yang, Q.S.; Wang, Y.S.; Sun, C.C.; Sun, H.Y.; Feng, J.B.; Jiang, Y.F.; Zhang, Y.Z.; Wu, M.L.; Dong, J.D. The diversity of coral associated bacteria and the environmental factors affect their community variation. Ecotoxicology, 2015, 24(7-8), 1467-1477.
[http://dx.doi.org/10.1007/s10646-015-1454-4] [PMID: 25833806]
[7]
Mahmoud, H.M.; Kalendar, A.A. Coral-associated actinobacteria: diversity, abundance, and biotechnological potentials. Front. Microbiol., 2016, 7, 204.
[http://dx.doi.org/10.3389/fmicb.2016.00204] [PMID: 26973601]
[8]
Hayashi, A.; Crombie, A.; Lacey, E.; Richardson, A.J.; Vuong, D.; Piggott, A.M.; Hallegraeff, G. Aspergillus sydowii marine fungal bloom in Australian coastal waters, its metabolites and potential impact on Symbiodinium dinoflagellates. Mar. Drugs, 2016, 14(3), 59.
[http://dx.doi.org/10.3390/md14030059] [PMID: 26999164]
[9]
Putria, D.A.; Radjasa, O.K.; Pringgenies, D. Effectiveness of marine fungal symbiont isolated from soft coral Sinularia sp. from Panjang Island as antifungal. Procedia Environ. Sci., 2015, 23, 351-357.
[http://dx.doi.org/10.1016/j.proenv.2015.01.051]
[10]
Shirur, K.P.; Jackson, C.R.; Goulet, T.L. Lesion recovery and the bacterial microbiome in two Caribbean gorgonian corals. Mar. Biol., 2016, 163, 238.
[http://dx.doi.org/10.1007/s00227-016-3008-6]
[11]
Salerno, J.L.; Bowen, B.W.; Rappé, M.S. Biogeography of planktonic and coral-associated microorganisms across the Hawaiian Archipelago. FEMS Microbiol. Ecol., 2016, 92(8)fiw109
[http://dx.doi.org/10.1093/femsec/fiw109] [PMID: 27222221]
[12]
Kuek, F.W.I.; Lim, L.F.; Ngu, L.H.; Mujahid, A.; Lim, P.T.; Leaw, C.P.; Müller, M. The potential roles of bacterial communities in coral defence: a case study at Talang-Talang reef. Ocean Sci. J., 2015, 50, 269-282.
[http://dx.doi.org/10.1007/s12601-015-0024-2]
[13]
Lema, K.A.; Clode, P.L.; Kilburn, M.R.; Thornton, R.; Willis, B.L.; Bourne, D.G. Imaging the uptake of nitrogen-fixing bacteria into larvae of the coral Acropora millepora. ISME J., 2016, 10(7), 1804-1808.
[http://dx.doi.org/10.1038/ismej.2015.229] [PMID: 26696324]
[14]
Shao, C.L.; Xu, R.F.; Wei, M.Y.; She, Z.G.; Wang, C.Y. Structure and absolute configuration of fumiquinazoline L, an alkaloid from a gorgonian-derived Scopulariopsis sp. fungus. J. Nat. Prod., 2013, 76(4), 779-782.
[http://dx.doi.org/10.1021/np4002042] [PMID: 23586849]
[15]
Shao, C.L.; Chao, R.; Xu, R.F.; Cao, F.; Wei, M.Y. Scopuquinolone A, a new terpenoids dihydroquinolone alkaloid from a gorgonian coral-derived Scopulariopsis sp. fungus. Chin. J. Mar. Drugs., 2016, 35, 1-5.
[16]
Shao, C.L.; Xu, R.F.; Wang, C.Y.; Qian, P.Y.; Wang, K.L.; Wei, M.Y. Potent antifouling marine dihydroquinolin-2(1H)-one-containing alkaloids from the gorgonian coral-derived fungus Scopulariopsis sp. Mar. Biotechnol. (NY), 2015, 17(4), 408-415.
[http://dx.doi.org/10.1007/s10126-015-9628-x] [PMID: 25833409]
[17]
Elnaggar, M.S.; Ebada, S.S.; Ashour, M.L.; Ebrahim, W.; Müller, W.E.G.; Mándi, A.; Kurtán, T.; Singab, A.; Lin, W.H.; Liu, Z.; Proksch, P. Xanthones and sesquiterpene derivatives from a marine-derived fungus Scopulariopsis sp. Tetrahedron, 2016, 72(19), 2411-2419.
[http://dx.doi.org/10.1016/j.tet.2016.03.073]
[18]
Elnaggar, M.S.; Ebada, S.S.; Ashour, M.L.; Ebrahim, W.; Singab, A.; Lin, W.; Liu, Z.; Proksch, P. Two new triterpenoids and a new naphthoquinone derivative isolated from a hard coral-derived fungus Scopulariopsis sp. Fitoterapia, 2017, 116, 126-130.
[http://dx.doi.org/10.1016/j.fitote.2016.12.003] [PMID: 27932272]
[19]
Jia, Y.L. Wei, M.Y.; Chen, H.Y.; Guan, F.F.; Wang, C.Y.; Shao, C.L. (+)-and (−)-Pestaloxazine A, a pair of antiviral enantiomeric alkaloid dimers with a symmetric spiro[oxazinane-piperazinedione] skeleton from Pestalotiopsis sp. Org. Lett., 2015, 17(17), 4216-4219.
[http://dx.doi.org/10.1021/acs.orglett.5b01995] [PMID: 26291636]
[20]
Wang, K.T.; Xu, M.Y.; Liu, W.; Li, H.J.; Xu, J.; Yang, D.P.; Lan, W.J.; Wang, L.Y. Two additional new compounds from the marine-derived fungus Pseudallescheria ellipsoidea F42-3. Molecules, 2016, 21(4), 442.
[http://dx.doi.org/10.3390/molecules21040442] [PMID: 27043524]
[21]
Lan, W.J.; Wang, K.T.; Xu, M.Y.; Zhang, J.J.; Lam, C.K.; Zhong, G.H.; Xu, J.; Yang, D.P.; Li, H.J.; Wang, L.Y. Secondary metabolites with chemical diversity from the marine-derived fungus Pseudallescheria boydii F19-1 and their cytotoxic activity. RSC Advances, 2016, 6(80), 76206-76213.
[http://dx.doi.org/10.1039/C6RA06661E]
[22]
Huang, L.H.; Chen, Y.X.; Yu, J.C.; Yuan, J.; Li, H.J.; Ma, W.Z.; Watanapokasin, R.; Hu, K.C.; Niaz, S.I.; Yang, D.P.; Lan, W.J. Secondary metabolites from the marine-derived fungus Dichotomomyces sp. L-8 and their cytotoxic activity. Molecules, 2017, 22(3), 444.
[http://dx.doi.org/10.3390/molecules22030444] [PMID: 28287456]
[23]
Liu, B.X.; Guo, Q.; Peng, G.T.; He, X.X.; Chen, X.J.; Lei, L.F.; Deng, Y.; Jun, Su. X.; Zhang, C.X.; Su, X.J. New cyclic tetrapeptide from the coral-derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea. Nat. Prod. Res., 2016, 30(1), 7-12.
[http://dx.doi.org/10.1080/14786419.2015.1026340] [PMID: 26214049]
[24]
Yu, Z.; Lang, G.; Kajahn, I.; Schmaljohann, R.; Imhoff, J.F. Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. J. Nat. Prod., 2008, 71(6), 1052-1054.
[http://dx.doi.org/10.1021/np070580e] [PMID: 18412398]
[25]
Kramer, A.; Labes, A.; Imhoff, J.F. Phylogenetic relationship and secondary metabolite production of marine fungi producing the cyclodepsipeptides scopularide A and B. Mar. Biotechnol. (NY), 2016, 18(4), 466-474.
[http://dx.doi.org/10.1007/s10126-016-9707-7] [PMID: 27209381]
[26]
Xing, Q.; Gan, L.S.; Mou, X.F.; Wang, W.; Wang, C.Y.; Wei, M.Y.; Shao, C.L. Isolation, resolution and biological evaluation of pestalachlorides E and F containing both point and axial chirality. RSC Advances, 2016, 6(27), 22653-22658.
[http://dx.doi.org/10.1039/C6RA00374E]
[27]
Xing, Q.; Li, D.; Guo, Z.Y.; Wang, C.Y.; Shao, C.L. Pestarhamnoses A-C, rhamnosylated phenol derivatives from the soft coral-derived fungus Pestalotiopsis sp. Chem. Nat. Compd., 2015, 51(6), 1080-1084.
[http://dx.doi.org/10.1007/s10600-015-1497-z]
[28]
Jia, Y.L.; Guan, F.F.; Ma, J.; Wang, C.Y.; Shao, C.L. Pestalotiolide A, a new antiviral phthalide derivative from a soft coral-derived fungus Pestalotiopsis sp. Nat. Prod. Sci., 2015, 21(4), 227-230.
[http://dx.doi.org/10.20307/nps.2015.21.4.227]
[29]
Sun, Y.Z.; Kurtán, T.; Mándi, A.; Tang, H.; Chou, Y.; Soong, K.; Su, L.; Sun, P.; Zhuang, C.L.; Zhang, W. Immunomodulatory polyketides from a Phoma-like fungus isolated from a soft coral. J. Nat. Prod., 2017, 80(11), 2930-2940.
[http://dx.doi.org/10.1021/acs.jnatprod.7b00463] [PMID: 29048894]
[30]
Zheng, C.J.; Shao, C.L.; Guo, Z.Y.; Chen, J.F.; Deng, D.S.; Yang, K.L.; Chen, Y.Y.; Fu, X.M.; She, Z.G.; Lin, Y.C.; Wang, C.Y. Bioactive hydroanthraquinones and anthraquinone dimers from a soft coral-derived Alternaria sp. fungus. J. Nat. Prod., 2012, 75(2), 189-197.
[http://dx.doi.org/10.1021/np200766d] [PMID: 22276679]
[31]
Zheng, C.J.; Shao, C.L.; Wu, L.Y.; Chen, M.; Wang, K.L.; Zhao, D.L.; Sun, X.P.; Chen, G.Y.; Wang, C.Y. Bioactive phenylalanine derivatives and cytochalasins from the soft coral-derived fungus, Aspergillus elegans. Mar. Drugs, 2013, 11(6), 2054-2068.
[http://dx.doi.org/10.3390/md11062054] [PMID: 23752358]
[32]
Zheng, C.J.; Shao, C.L.; Chen, M.; Niu, Z.G.; Zhao, D.L.; Wang, C.Y. Merosesquiterpenoids and ten-membered macrolides from a soft coral-derived Lophiostoma sp. fungus. Chem. Biodivers., 2015, 12(9), 1407-1414.
[http://dx.doi.org/10.1002/cbdv.201400331] [PMID: 26363884]
[33]
Zheng, C.J.; Fu, X.M.; Zhang, X.L.; Kong, W.W.; Wang, C.Y. Bioactive perylene derivatives from a soft coral-derived fungus Alternaria sp. (ZJ-2008017). Chem. Nat. Compd., 2015, 51(4), 766-768.
[http://dx.doi.org/10.1007/s10600-015-1406-5]
[34]
Tsuda, M.; Mugishima, T.; Komatsu, K.; Sone, T.; Tanaka, M.; Mikami, Y.; Kobayashi, J. Modiolides A and B, two new 10-membered macrolides from a marine-derived fungus. J. Nat. Prod., 2003, 66(3), 412-415.
[http://dx.doi.org/10.1021/np0203943] [PMID: 12662103]
[35]
Hawas, U.W.; El-Desouky, S.; Abou El-Kassem, L.; Elkhatee, W. Alternariol derivatives from Alternaria alternate, an endophytic fungus residing in Red Sea soft coral, inhibit HCV NS3/4A protease. Appl. Biochem. Microbiol., 2015, 51(5), 579-584.
[http://dx.doi.org/10.1134/S0003683815050099]
[36]
Hamed, A.; Abdel-Razek, A.S.; Frese, M.; Wibberg, D.; El-Haddad, A.F.; Tarek, M.A.; Ibrahim, T.M.A.; Kalinowski, J.; Sewald, N.; Shaaban, M. New oxaphenalene derivative from marine-derived Streptomyces Griseorubens sp. ASMR4. Z. Naturforsch., 2017, 72(1), 53-62.
[http://dx.doi.org/10.1515/znb-2016-0145]
[37]
Burkhardt, H.J.; Forgacs, J. O-methylsterigmatocystin, a new metabolite from Aspergillus flavus, link ex fries. Tetrahedron, 1968, 24(2), 717-720.
[http://dx.doi.org/10.1016/0040-4020(68)88020-2]
[38]
Bradner, W.T.; Bush, J.A.; Myllymaki, R.W.; Nettleton, D.E., Jr; O’Herron, F.A. Fermentation, isolation, and antitumor activity of sterigmatocystins. Antimicrob. Agents Chemother., 1975, 8(2), 159-163.
[http://dx.doi.org/10.1128/AAC.8.2.159] [PMID: 1180542]
[39]
Wei, M.Y.; Wang, C.F.; Wang, K.L.; Qian, P.Y.; Wang, C.Y.; Shao, C.L. Preparation, structure, and potent antifouling activity of sclerotioramine derivatives. Mar. Biotechnol. (NY), 2017, 19(4), 372-378.
[http://dx.doi.org/10.1007/s10126-017-9760-x] [PMID: 28688034]
[40]
Wolff, K.A.; Nguyen, H.T.; Cartabuke, R.H.; Singh, A.; Ogwang, S.; Nguyen, L. Protein kinase G is required for intrinsic antibiotic resistance in mycobacteria. Antimicrob. Agents Chemother., 2009, 53(8), 3515-3519.
[http://dx.doi.org/10.1128/AAC.00012-09] [PMID: 19528288]
[41]
Chen, D.; Ma, S.; He, L.; Yuan, P.; She, Z.; Lu, Y. Sclerotiorin inhibits protein kinase G from Mycobacterium tuberculosis and impairs mycobacterial growth in macrophages. Tuberculosis (Edinb.), 2017, 103, 37-43.
[http://dx.doi.org/10.1016/j.tube.2017.01.001] [PMID: 28237032]
[42]
Shao, C.L.; Wu, H.X.; Wang, C.Y.; Liu, Q.A.; Xu, Y.; Wei, M.Y.; Qian, P.Y.; Gu, Y.C.; Zheng, C.J.; She, Z.G.; Lin, Y.C. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J. Nat. Prod., 2011, 74(4), 629-633.
[http://dx.doi.org/10.1021/np100641b] [PMID: 21348465]
[43]
Zhang, X.Q.; Spadafora, C.; Pineda, L.M.; Ng, M.G.; Sun, J.H.; Wang, W.; Wang, C.Y.; Gu, Y.C.; Shao, C.L. Discovery, semisynthesis, antiparasitic and cytotoxic evaluation of 14-membered resorcylic acid lactones and their derivatives Sci. Rep.-UK,, 2017, 7(1), 11822.
[http://dx.doi.org/10.1038/s41598-017-12336-0] [PMID: 28924201]
[44]
Liao, H.X.; Sun, D.W.; Zheng, C.J.; Wang, C.Y. A new hexahydrobenzopyran derivative from the gorgonian-derived fungus Eutypella sp. Nat. Prod. Res., 2017, 31(14), 1640-1646.
[http://dx.doi.org/10.1080/14786419.2017.1285301] [PMID: 28278631]
[45]
Shi, T.; Qi, J.; Shao, C.L.; Zhao, D.L.; Hou, X.M.; Wang, C.Y. Bioactive diphenyl ethers and isocoumarin derivatives from a gorgonian-derived fungus Phoma sp. (TA07-1). Mar. Drugs, 2017, 15(6), 146.
[http://dx.doi.org/10.3390/md15060146] [PMID: 28587090]
[46]
Zhu, M.; Gao, H.; Wu, C.; Zhu, T.; Che, Q.; Gu, Q.; Guo, P.; Li, D. Lipid-lowering polyketides from a soft coral-derived fungus Cladosporium sp. TZP29. Bioorg. Med. Chem. Lett., 2015, 25(17), 3606-3609.
[http://dx.doi.org/10.1016/j.bmcl.2015.06.072] [PMID: 26169125]
[47]
Braña, A.F.; Sarmiento-Vizcaíno, A.; Osset, M.; Pérez-Victoria, I.; Martín, J.; de Pedro, N.; de la Cruz, M.; Díaz, C.; Vicente, F.; Reyes, F.; García, L.A.; Blanco, G. Lobophorin K, a new natural product with cytotoxic activity produced by Streptomyces sp. M-207 associated with the deep-sea coral Lophelia pertusa. Mar. Drugs, 2017, 15(5), 144.
[http://dx.doi.org/10.3390/md15050144] [PMID: 28534807]
[48]
Raina, J.B.; Tapiolas, D.; Motti, C.A.; Foret, S.; Seemann, T.; Tebben, J.; Willis, B.L.; Bourne, D.G. Isolation of an antimicrobial compound produced by bacteria associated with reef-building corals. PeerJ, 2016, 4e2275
[http://dx.doi.org/10.7717/peerj.2275] [PMID: 27602265]
[49]
Raina, J.B.; Tapiolas, D.M.; Forêt, S.; Lutz, A.; Abrego, D.; Ceh, J.; Seneca, F.O.; Clode, P.L.; Bourne, D.G.; Willis, B.L.; Motti, C.A. DMSP biosynthesis by an animal and its role in coral thermal stress response. Nature, 2013, 502(7473), 677-680.
[http://dx.doi.org/10.1038/nature12677] [PMID: 24153189]
[50]
Yu, M.L.; Guan, F.F.; Cao, F.; Jia, Y.L.; Wang, C.Y. A new antiviral pregnane from a gorgonian-derived Cladosporium sp. fungus. Nat. Prod. Res., 2018, 32(11), 1260-1266.
[http://dx.doi.org/10.1080/14786419.2017.1342086] [PMID: 28641456]

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