Title:Comparison of the Mean Minimum Dose of Bolus Oxytocin for Proper Uterine Contraction during Cesarean Section
Volume: 14
Issue: 3
Author(s): Siavash Beiranvand, Arash Karimi, Sepideh Vahabi*Arash Amin-Bidokhti
Affiliation:
- Department of Anesthesiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad,Iran
Keywords:
Caesarean section, oxytocin, cervical dilatation, dystocia, intravenous, dysrhythmia.
Abstract: Background: Cesarean section is the most common midwifery operation. The aim of
this study is to determine the mean minimum dose of bolus oxytocin for proper uterine contraction
during cesarean section.
Methods: Patients were divided into two groups: elective cesarean section (n=41) and cesarean
section due to difficulty in labor (n=42 patients). Patients underwent spinal anesthesia and oxytocin
infusion was begun at 30 drops per minute (20 units of oxytocin per 1000 cc serum), and was also
administered as a half-dose in cc to achieve effective contraction of the uterus. Meanwhile, the information
of patients including systolic and diastolic blood pressure (SBP and DBP), heart rate and
amount of bleeding during the operation was recorded in a questionnaire.
Results: In the elective cesarean section group, the average SBP was about 117.10mmHg, average
DBP 70.50 mmHg, the amount of bleeding during surgery was 623.63mL, and heart rate was
88.88bpm. In the cesarean section group due to difficulty in labor progress, SBP was 113.5 mmHg,
DBP 62.69 mmHg, and bleeding was 573.81mL. In addition, 9 patients in the elective group and 3
patients in the lack of progress group, did not require bolus oxytocin. In the lack of a progress
group, 8 patients needed more than 5 doses of oxytocin. In addition, about 10 (12%) of all patients
had no side effects, and hypotension.
Conclusion: Given that, the minimum effective dose of oxytocin in the elective cesarean section
was 1IU, and in those in labor progress was 1-1.5IU, less oxytocin administration represents lesser
side effects. It is recommended that patients who are candidates of cesarean section should be administered
1.5IU of oxytocin in the form of bolus.
