Title:The Effects of Hemocoagulase on Coagulation Factors in an Elderly Patient with Upper Gastrointestinal Hemorrhage: A Case Report
Volume: 14
Issue: 3
Author(s): Haiyan Zhang*
Affiliation:
- Department of General Practice, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou,China
Keywords:
Hemocoagulase agkistrodon, hypofibrinogenemia, gastrointestinal hemorrhage, enzymes, fibrinopeptide, Coagulation
disorder.
Abstract:
Background: Hemocoagulase agkistrodon has been widely used for visceral bleeding,
however, its adverse reaction has not been fully recognized.
Case Report: A 65-year-old female with upper gastrointestinal hemorrhage occurred severe coagulation
disorder during her hospitalization. Transfusion of blood products can not improve coagulation
function. Coagulation parameters returned to normal two days after discontinuation of hemocoagulase
agkistrodon.
Conclusion: So intravenous administration of hemocoagulase should be cautiously used for the
treatment of gastrointestinal bleeding.