Title:Acute Leriche Syndrome in Pancreatic Adenocarcinoma: A Case Report
Volume: 16
Author(s): Eftychia Mosa, Stamo Manouvelou, Maria Tolia*, Nikolaos Tsoukalas, Alexandros Ardavanis, Myrsini Stasinopoulou, George Kyrgias and Aggeliki Tavernaraki
Affiliation:
- Department of Radiotherapy, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larisa,Greece
Keywords:
Pancreatic cancer, leriche syndrome, chemotherapy, MDCTA, carcinoma, tumor.
Abstract:
Introduction: Coexistance of pancreatic carcinoma and Leriche syndrome is an extremely
rare pathological condition. Leriche syndrome is defined as occlusion of the distal aorta at
the bifurcation into the common iliac arteries.
Case Report: We report the case of a 57-year old male patient with a locally advanced pancreatic
tumor that during chemotherapy presented Leriche syndrome. Four months after the diagnosis and
although the initial staging by MRI had only revealed a few atheromatic lesions of the abdominal
aorta, the patient complained about claudication of the legs and hypoesthesia. Angiography with
multi-detector computed tomography (MDCTA) was performed using aortography protocol and
three-dimensional reconstruction of the images followed, demonstrating the relationship between
pancreatic carcinoma and Leriche syndrome.
Conclusion: Review of the literature revealed that acute abdominal thrombosis is rare in cancer
patients. To our knowledge, complete occlusion of the aorta in a patient with pancreatic cancer has
not been reported yet.
