Title:Clinical Research on the Aortic Elasticity in Patients with Type 1 Diabetes Mellitus Complicated with Hypertension
Volume: 15
Author(s): Zheng Wang and Yulei Wan*
Affiliation:
- Department of Radiology, Wuhan No. 6 Hospital Affiliated to Jianghan University, Wuhan,China
Keywords:
X-ray computed tomography, hypertension, type 1 diabetes mellitus, thoracic aorta, elasticity, quantitative analysis.
Abstract:
Objective: To investigate the characteristics of aortic elasticity in type 1 diabetes mellitus
(DM1) patients with hypertension using dual-source computed tomography (DSCT).
Methods: Subjects were divided into four groups: 31 with hypertension (EH group), 28 with DM1
(DM1 group), 30 with hypertension and DM1 (DM1 + EH group), and 30 healthy volunteers (control
group, CG). ECG-gated DSCT was used to measure the cross-sectional area of the aorta in diastole
and systole and calculate the aortic elasticity (D). Analysis of variance and multiple linear regression
were used for statistical analysis.
Results: Compared with the CG, aortic elasticity (D) in the DM1 group patients was not significantly
decreased. Compared with the EH group, the DM1 + EH group showed no significant change.
The aortic elasticity (D) in the EH and DM1 + EH groups was significantly lower than that in the
CG and DM1 group.
Conclusion: DM1 slightly affects the aortic elasticity of the descending aorta, whereas hypertension
exerts the main effect.