Title:Study the Effect of PG E1 and PGF2α on Male Rat Reproductive Functions
Volume: 18
Issue: 1
Author(s): Ali Esmail Al Snafi*, Khalid G. Al-Fartosi and Zainab Qasim Al-Yasiry
Affiliation:
- Department of Pharmacology, College of Medicine, University of Thi Qar, Nasiriyah,Iraq
Keywords:
Reproduction, PGE1 , PGF2α, male, rats, LH, FSH, testosterone.
Abstract: Background: This research was performed to investigate the effects of prostaglandins
on the sexual functions of albino male rats. The effects of prostaglandins on LH,
FSH, testosterone secretion and semen quality of the male rats were investigated. PGE1
induced a significant decline in the level of LH, FSH and testosterone levels. PGE1 also
induced significant decline in the testis, epididymal and seminal vesicle weights.
Conclusion: Furthermore, PGE1 caused significant reduction in sperm count, and significant
decline in the viable and malformed sperm percent. However, PGF2α did not affect
these parameters.
