Title:Ionic Liquid Promoted Eco-friendly and Efficient Synthesis of Six-membered Npolyheterocycles
Volume: 15
Issue: 8
Author(s): Navjeet Kaur*
Affiliation:
- Department of Chemistry, Banasthali Vidyapith, Banasthali-304022 (Rajasthan),India
Keywords:
Ionic liquid, nitrogen, heterocycles, green chemistry, N-polyheterocycles, organic synthesis.
Abstract: Background: The synthesis of N-polyheterocycles by environmentally benign method is highly attractive
but challenging proposition. New strategies have been developed for the preparation of polycyclic heterocycles
in the last decades. In this review article, the synthesis of nitrogen containing six-membered polycyclic
heterocyclic compounds is presented with the application of ionic liquids. This contribution focuses on
the literature related to the total synthesis of six-membered N-polyheterocycles.
Objective: Ionic liquids not only acted as environmentally benign reaction media but also as catalysts which
afforded the very promising replacements of traditional molecular solvents in organic chemistry due to their
stability, non-flammability, non-volatility and ease of recyclability. Ionic liquids are utilized in metal catalyzed
reactions in place of organic solvents in the last years. It has attracted considerable attention in recent years.
Ionic liquids acted as alternatives of organic solvents and these ILs are environment friendly.
Conclusion: In the area of green chemistry ionic liquid assisted synthesis is a very promising technique which
afforded a flexible platform for the formation of heterocycles. The influence of ILs on the development of efficient
and new synthetic protocols over the last decade for the construction of N-polyheterocycles is featured in
this review article. These synthetic strategies will continue to attract more attention and will find a wide range
of applications in organic synthesis. In conclusion, ionic liquids assisted syntheses have become an efficient
and powerful tool in organic chemistry quickly.
