摘要
进行性核上性瘫痪是一种以帕金森病、动眼神经功能异常、早期体位不稳和认知障碍为特征的进行性神经退行性疾病,PSP中的神经变性与τ蛋白有关,但导致细胞功能障碍和死亡的机制尚不清楚。 与害怕和丧失自理能力有关的神经行为问题可以决定许多生物伦理问题。需要仔细规划病人的家庭、学术和行业研究人员,以确保生活质量的提高。
关键词: 进行性核上性麻痹、扁桃体病、运动障碍、生物伦理学、临床伦理学、认知疾病。
Current Alzheimer Research
Title:Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects
Volume: 15 Issue: 10
关键词: 进行性核上性麻痹、扁桃体病、运动障碍、生物伦理学、临床伦理学、认知疾病。
摘要: The progressive supranuclear palsy is a progressive neurodegenerative disease characterized by Parkinsonism, oculomotor abnormalities, early postural instability and cognitive impairment. Neurodegeneration in PSP is associated with tau protein, but the mechanisms by which tau abnormalities lead to cell dysfunction and death are not well understood.
Neuro-behavioural problems related to the fear and loss of autonomy can determinate many bioethical implications. Careful planning involving patients’ families, academic and industry researchers were necessary to ensure improvement in quality of life.
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Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects, Current Alzheimer Research 2018; 15 (10) . https://dx.doi.org/10.2174/1567205015666180507111958
DOI https://dx.doi.org/10.2174/1567205015666180507111958 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
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