Tumor Escape from Immune Response: Mechanisms and Targets of Activity

Title: Tumor Escape from Immune Response: Mechanisms and Targets of Activity

Volume: 4 Issue: 7

Author(s): Dmitry Gabrilovich and Vladimir Pisarev

Affiliation:

Keywords: Immune, tumor cells, antigen-presenting cells

Abstract: Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.

Cite this article as:

Gabrilovich Dmitry and Pisarev Vladimir, Tumor Escape from Immune Response: Mechanisms and Targets of Activity, Current Drug Targets 2003; 4 (7) . https://dx.doi.org/10.2174/1389450033490849