Title:Current Screening Tests and Novel Early Detection Approaches for Alzheimer's Disease
Volume: 5
Issue: 2
Author(s): Mohd Usairy Syafiq, Jiajia Yang*, Yinghua Yu and Jinglong Wu*
Affiliation:
- Biomedical Engineering Laboratory, Graduate School of Natural Science and Technology, Okayama University, Okayama,Japan
- Biomedical Engineering Laboratory, Graduate School of Natural Science and Technology, Okayama University, Okayama,Japan
Keywords:
Alzheimer, behavior, intellectual functioning, cognitive impairment, hypertension, diabetes.
Abstract: Brief cognitive screening tests performed by primary care physicians provide effective information
for Alzheimer's patients and families regarding recent changes in daily living, behavior, intellectual
functioning, and mood. In this review, we consider information in the literature concerning the practicality
and accuracy of brief cognitive screening instruments currently utilized in primary care. Nine brief screening
tests met our inclusion criteria and we discuss the characteristics, applicability, challenges, and development
of each. We also review the relevance of the tactile sense, a novel element that improves the sensitivity of
current screening methods. Finally, we discuss how new approaches involving tactile discrimination may
offer the ability to discriminate patients with Alzheimer's disease from normal subjects.