Title:2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances
Volume: 14
Issue: 5
Author(s): Luana da S. M. Forezi, Mariana F. C. Cardoso, Dora C. S. Costa, Fernando de C. da Silva and Vitor F. Ferreira*
Affiliation:
- Universidade Federal Fluminense, Departamento de Química Orgânica, Programa de Pós- Graduação em Química, Outeiro de São João Baptista, 24020-141 Niterói, RJ,Brazil
Keywords:
Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions,
napthoquinone.
Abstract: 2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for
applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives
and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for
the preparation of compounds for evaluation against several biological targets. This review will describe the
most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
