Title:Flavonoids as Multi-Target Compounds in Drug Discovery
Volume: 14
Issue: 4
Author(s): L. Scotti*, H. Ishiki, F.J.B. Mendonça Júnior, R.M.D. Cruz, J.F. Tavares, M.F.F.M. Diniz, J.M. Barbosa Filho and M.T. Scotti
Affiliation:
- Health Sciences Center, Federal University of Paraíba, Campus I, 58051-970, João Pessoa-PB,Brazil
Keywords:
Flavonoids, multi-target, drug, neurodegenerative, cancer, parasite, inflammation.
Abstract: With the aim of offering patients a more effective drug therapy and with few side effects, it
was believed in the perfect and unique interaction of the bioactive compound and the receptor or target
macromolecule. This concept has changed, and multifunctional compounds show greater efficiency,
particularly in the therapy of complex diseases, with a sum of origin. Among these ills, we quote: neurodegenerative
diseases, cancer, parasitic and inflammatory. To fight these diseases, studies with multitarget
flavonoids have been reported. Flavonoid compounds are natural products traditionally used as
chemotherapy because of their numerous therapeutic activities. Here, we gather studies with multitarget
in drug discovery flavonoids.
