Title:Pomegranate as a Possible Treatment in Reducing Risk of Developing Wound Healing, Obesity, Neurodegenerative Disorders, and Diabetes Mellitus
Volume: 18
Issue: 6
Author(s): Manaf AlMatar*, Md Rashedul Islam, Osman Albarri, Isil Var and Fatih Koksal
Affiliation:
- Institute of Natural and Applied Sciences (Fen Bilimleri Enstitüsü), Department of Biotechnology, Cukurova University, 01330 Balcali, Adana,Turkey
Keywords:
P. granatum, wound healing, ellagitannins, neurodegenerative diseases, obesity, diabetes mellitus, punicic acid.
Abstract: Four distinguished although overlying stages make up the methodical procedure of wound
healing, which are hemostasis, inflammation, proliferation and remodelling. Multiple sclerosis (MS) is
described as an incessant inflammatory central nervous system disease, and is linked with neurodegeneration,
demyelination, as well as susceptibility to oxidative pressure. Obesity signifies a swiftly developing
danger to the wellbeing of populations in a rising number of nations. Usually called diabetes
mellitus (DM) by medical practitioners, diabetes details a collection of metabolic diseases within
which the individual has raised blood glucose, either due to an insufficiency of insulin generation, or
the lack of suitable response by the body to insulin, or both. Conventionally, the pomegranate, as well
as its flowers, leaves, fruit juice and tree bark, has been applied in the treatment of conditions including
acidosis, haemorrhage, diarrhoea and microbial contagions. Extracts of pomegranate have been established
to contain intense anti-inflammatory, antioxidant as well as antitumor features in vivo as well as
ex vivo. Of late, beneficial consequences of decrease of fat have been illustrated employing the pomegranate
as well as its extracts. Several of the favourable consequences are associated with the availability
of anthocyanins, tannins, and considerably elevated amounts of antioxidants, as well as flavonoids
and polyphenols. A summary of the endeavours applied to deal with the possible advantages of the
pomegranate towards healing wounds, Alzheimer's disease (AD), diabetes mellitus (DM) and obesity,
as well as an appraisal of the efficiency of intervention through the pomegranate and its extracts is
provided in this article.
