Title:An Overview of Currently Available Antimalarials
Volume: 17
Issue: 19
Author(s): Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam and Brijesh Rathi*
Affiliation:
- Department of Chemistry of Heterocyclic Compounds, State Scientific Institution “Institute for Single Crystals”, National Academy of Science of Ukraine, Nauky ave. 60, Kharkiv, 61001,Ukraine
- Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi-110007,India
Keywords:
Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.
Abstract: Background: Despite the substantial progress over the time, malaria remains a major public
health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial
therapy increases threat to the global public health.
Objective: Overview of currently available antimalarials.
Method: Literary survey.
Results: The summarized data about different types of antimalarial therapies and their efficiency and
modes of action.
Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment,
this arsenal is limited due to the narrow variation of their mechanism of action.