Title:Non-Melanoma Skin Cancer – Overview
Volume: 12
Issue: 3
Author(s): Kurian Joseph
Affiliation:
Keywords:
Non-melanoma skin cancer, MMS, PDT, BCC, SCC.
Abstract: Non-Melanoma Skin Cancer (NMSC) is the most common form of skin cancer.
Common risk factors linked to the occurrence of NMSC are occupational exposure to
chemicals, ultraviolet light exposure, immunosuppresion, human papillomavirus infection,
artificial tanning, premalignant skin lesions and inherited skin conditions. The various
clinical manifestations of NMSC depend on location and subtype. Management of NMSC
includes pathology confirmation, staging and treatment. Retinoid and nicotinamide have
been shown to be effective for the prevention of NMSC, primary treatments available for
the treatment of NMSC are wide local excision, Mohs micrographic surgery (MMS), radiotherapy
(RT), topical agents (5FU cream) and photodynamic therapy (PDT).
The choice of definite treatment depends on many factors such as performance status and
age of the patient, location and size of the tumor, etc.
