Title:Anticancer Drug Development, System Updating and Global Participations
Volume: 12
Issue: 1
Author(s): Da-Yong Lu*, Ting-Ren Lu, En-Hong Chen, Nagendra Sastry Yarla, Bin Xu, Jian Ding and Hong Zhu
Affiliation:
- School of Life Sciences, Shanghai University, Shanghai 200444,China
Keywords:
Anticancer drug development, neoplasm metastasis, cost-effective, medicinal chemistry,
animal models, drug toxicity, cancer stem cells, individualized cancer therapy.
Abstract: Background: New anticancer drug discovery, development and manufacture
entered the bottleneck stage. Many limitations of both technology and animal models slow
down the anticancer drug developments
Objective: To ease economic burdens for drug developers and general patient populations.
Methods: Key factors affecting anticancer drug developments and possible roadmaps for
updating drug screening routines worldwide are suggested.
Results: Drug development chains must be updated and better drug development paradigms
must be established.
Conclusions: This world welcomes global participations in anticancer drug developments
and utilities.