摘要
背景:心脏肿瘤罕见心脏病发病率总体发生率<0.33%。根据肿瘤的起源,心脏肿瘤可以分为原发性或继发性。原发性心脏肿瘤(5%发生率)与次要(95%,心脏转移)心脏肿瘤相比是罕见的。 目的:鉴于与其他心脏病相比,心脏肿瘤显示出一些非特异性症状,心脏肿瘤的临床诊断相当具有挑战性。因此,我们将尝试回顾心脏肿瘤的分类和发病机制。 结论:目前的证据显示,75%的心脏肿瘤被认为是良性的(粘液瘤,纤维瘤,脂肪瘤,横纹肌瘤,血管瘤,畸胎瘤,乳头状纤维母细胞瘤,心房囊肿或房室结囊性囊肿)。心脏肿瘤的临床鉴别诊断主要基于成像技术,包括经胸和经食管超声心动图,计算机断层扫描(CT)扫描和磁共振成像(MRI)。这个小型评论试图总结最近对心脏肿瘤的发病机制和治疗方法的理解。
关键词: 心脏,肿瘤,治疗,良性,恶性,发病机制。
Current Drug Targets
Title:Cardiac Tumors: Clinical Perspective and Therapeutic Considerations
Volume: 18 Issue: 15
关键词: 心脏,肿瘤,治疗,良性,恶性,发病机制。
摘要: Background: Cardiac tumors rare cardiac disorders with an overall incidence rate < 0.33%. Cardiac tumors can be classified as primary or secondary depending on the origins of tumors. Primary cardiac tumors (5% incidence) are rare compared with the secondary (95%, metastases of the heart) cardiac tumors.
Objective: Given that cardiac tumors exhibit some nonspecific symptoms compared with other heart diseases, clinical diagnosis of cardiac tumors is rather challenging. Thus we will try to review the classification and pathogenesis of cardiac tumors.
Conclusion: Current evidence revealed that 75% of cardiac tumors are considered benign (myxoma, fibromas, lipomas, rhabdomyomas, hemangiomas, teratomas, papillary fibroelastomas, pericardial cysts or cystic tumor of atrioventricular node). Clinical differential diagnosis of cardiac tumors is mainly based on imaging techniques including transthoracic and transesophageal echocardiograms, computed tomography (CT) scans and magnetic resonance imaging (MRIs). This mini-review tries to summarize recent understanding of the pathogenesis and therapeutics of cardiac tumors.
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Cite this article as:
Cardiac Tumors: Clinical Perspective and Therapeutic Considerations, Current Drug Targets 2017; 18 (15) . https://dx.doi.org/10.2174/1389450117666160703162111
DOI https://dx.doi.org/10.2174/1389450117666160703162111 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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