Title:Small RNAs Play Big Roles: MicroRNAs in Diabetic Wound Healing
Volume: 16
Issue: 6
Author(s): F. Fahs, X.-L. Bi, F.-S. Yu, L. Zhou and Q.-S. Mi
Affiliation:
Keywords:
microRNA, wound healing, skin, cornea, diabetes, pathogenesis.
Abstract: Skin and corneal wounds in diabetics are a major healthcare burden. MicroRNAs
are small, non-coding RNAs that post-transcriptionally regulate the expression of proteincoding
genes. Studies have identified microRNAs involved in all phases of wound healing.
The dysregulation of microRNAs can contribute to impaired or delayed skin and corneal
wound healing in diabetics. Here, we present a comprehensive review of the literature
involving microRNAs in diabetic skin and corneal wound healing as well as those serving as
potential biomarkers for diabetic wound healing.
