Title:Benzothiazole Derivatives as Potential Anti-Infective Agents
Volume: 17
Issue: 2
Author(s): Prabodh Chander Sharma, Kushal Kumar Bansal, Aakash Deep and Meenakshi Pathak
Affiliation:
Keywords:
Benzothiazole, Synthesis, Click Chemistry, Anti-infective activity, Chemotherapy.
Abstract: Background: Severity of microbial infections and escalating resistance towards antibiotics
has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of
benzothiazole has become one of the most prolific areas in the field of drug discovery and development
that has attracted great attention in recent time due to its increasing importance in the field of
pharmaceuticals.
Method: The importance of benzothiazole and derivatives as potential antimicrobial agents has been
well established and a large number of papers have been published in this regard.
Result: The present communication is an earnest attempt to review the chemistry, synthetic aspects
including click chemistry and antimicrobial activities of benzothiazole derivatives reported in recent
scientific literature.
Conclusion: The scientific information of this manuscript may be worthwhile in encouraging the prospective
researchers working on this heterocyclic scaffold.
