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摘要
老年痴呆症患者常见痴呆的行为和精神症状(BPSD)。BPSD对病人和照顾者有着重大的影响。关于BPSD治疗的药理学方法可用的文献是稀少的,有时呈现不一致的结果。没有FDA批准用于BPSD治疗的药物,老年人群痴呆可用药物的使用与明显的副作用有关。此文概述了BPSD的评估,探讨了药物管理的总则,并审查了目前非药物和药物治疗策略以及相关风险的证据。
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
Current Alzheimer Research
Title:The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks
Volume: 13 Issue: 10
Author(s): Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens
Affiliation:
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
摘要: Behavioral and psychological symptoms of dementia (BPSD) are common among patients with dementia. BPSD have significant implications on outcomes for patients and caregivers. Available literature for pharmacological approaches to BPSD is sparse and at times inconsistent. There are no FDA-approved medications for the management of BPSD, and the use of available medications is associated with significant adverse effects among aged populations with dementia. This review outlines the assessment of BPSD, discusses general principles of management, and examines current evidence for non-pharmacologic and pharmacologic treatment strategies as well as associated risks.
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Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens , The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks, Current Alzheimer Research 2016; 13 (10) . https://dx.doi.org/10.2174/1567205013666160510121633
DOI https://dx.doi.org/10.2174/1567205013666160510121633 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
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