The Effect of Non-Thermal Microwave-Treated Physiological Solution on Isolated Heart Muscle of Snail

Title:The Effect of Non-Thermal Microwave-Treated Physiological Solution on Isolated Heart Muscle of Snail

Volume: 10 Issue: 1

Author(s): Gayane Ayrapetyan, Hovik Hayrapetyan and Sinerik Ayrapetyan

Affiliation:

Keywords: Non-thermal, MW, Heart muscle, Intracellular Ca²⁺, cGMP, Muscle hydration.

Abstract: The effects of non-thermal intensity of microwave (NT MW)- treated physiological solutions (PS) on muscle contractility, ⁴⁵Ca uptake by muscle and muscle hydration of snail isolated heart in normal and K⁺-free PS were studied. The intra-cordial perfusion by NT MW-treated PS led to inhibition of heart beating with gradual decrease of the amplitudes of muscle contraction, the weakness of the Na⁺/K⁺ pump-induced transient inhibition of heart beating (TIHB), the inhibition of ⁴⁵Ca²⁺ uptake by muscle, the increase of intracellular cGMP contents and muscle dehydration. The obtained data serve as additional evidence for hypothesis that cell bathing aqua solution is a primary target for non-thermal effect of MW on cells and organisms.

Cite this article as:

Ayrapetyan Gayane, Hayrapetyan Hovik and Ayrapetyan Sinerik, The Effect of Non-Thermal Microwave-Treated Physiological Solution on Isolated Heart Muscle of Snail, Current Chemical Biology 2016; 10 (1) . https://dx.doi.org/10.2174/2212796810666160419152816