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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

Chemical Retraction Agents – in vivo and in vitro Studies into their Physico-Chemical Properties, Biocompatibility with Gingival Margin Tissues and Compatibility with Elastomer Impression Materials

Author(s): Danuta Nowakowska, Jolanta Saczko, Julita Kulbacka and Wlodzimierz Wicckiewicz

Volume 17, Issue 5, 2017

Page: [435 - 444] Pages: 10

DOI: 10.2174/1389557516666160418122701

Price: $65

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Abstract

Gingival margin retraction/displacement (GMR/D) is a commonly accepted procedure in restorative dentistry. Of the various retraction methods, the chemo-mechanical approach with retraction media and chemical retraction agents (ChRAs) is mostly used. Different local and/or systemic side effects were observed after “chemical attacks” from these retraction agents. Moreover, no consensus exists as to the compatibility of chemical agents with different impression materials. This paper reports the findings of in vivo and in vitro studies and we discuss the physico-chemical properties of chemical retraction agents, their undesirable clinical side effects, biological activity and compatibility with selected groups of elastomer impression materials.

Keywords: Chemical retraction agents, compatibility, cytotoxicity, gingival margin retraction.


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