摘要
灰指甲(指甲真菌感染)是非常常见的并广泛存在的,但幸好不常致死。近年来,一些功能强大的药物已被引入临床实践,但主要是由于药物在治疗浓度的感染部位的渗透的难度,这些感染仍然很难治愈。本综述讨论了该病的性质、致病真菌、用于治疗这种疾病的药物的特点。
关键词: 抗真菌药物,灰指甲,皮肤癣菌,灰黄霉素,唑类,多烯大环内酯类,烯丙基胺,环吡酮胺,tavaborole,茶树油。
Current Medicinal Chemistry
Title:Onychomycosis and its Chemotherapy
Volume: 23 Issue: 16
Author(s): Anwer Basha, Fatima Basha, Syed K. Ali, Paul R. Hanson, Berl R. Oakley, Heather Hajovsky, Lester A. Mitscher
Affiliation:
关键词: 抗真菌药物,灰指甲,皮肤癣菌,灰黄霉素,唑类,多烯大环内酯类,烯丙基胺,环吡酮胺,tavaborole,茶树油。
摘要: Onychomycosis (fungal nail infections) is very common worldwide but is fortunately not often lethal. Several powerful drugs have been introduced into clinical practice in recent years, but these infections remain difficult to cure primarily due to the difficulty of penetration of drug to the site of the infection in therapeutic concentrations. The nature of the disease, the causative fungi, and the characteristics of the drugs employed to treat this condition are discussed in this review.
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Cite this article as:
Anwer Basha, Fatima Basha, Syed K. Ali, Paul R. Hanson, Berl R. Oakley, Heather Hajovsky, Lester A. Mitscher , Onychomycosis and its Chemotherapy, Current Medicinal Chemistry 2016; 23 (16) . https://dx.doi.org/10.2174/0929867323666160411130103
DOI https://dx.doi.org/10.2174/0929867323666160411130103 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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