Title:Reproductive Health Indicators and Factors Affecting Menstrual Cycle Pattern among Sudanese Women with Thyroid Dysfunction
Volume: 11
Issue: 2
Author(s): Khalid Yassin, Maisa Sharif, Abd Elmohsine Abulea, Amel Kamil and Abdel Aziem A. Ali
Affiliation:
Keywords:
Menstrual cycle, pregnancy, reproductive, Sudan, thyroid.
Abstract: This was a cross sectional hospital based study conducted at Khartoum Teaching Hospital,
Sudan, during the period of June-through December 2013 to investigate the reproductive health
indicators and the factors affecting menstrual cycle pattern among women with thyroid dysfunction. A
total of 210 women had been enrolled, 128 (61.0%) were married, and 72(39%) were single. Of the
total respondents 51.9%, 46.2% and 1.9% (4) had hypothyroidism, hyperthyroidism and thyroiditis
respectively. Among the total respondents 53.9% have normal menstrual cycle pattern, 19% suffered
from polymenorrhea, 12.4% reported oligomenorrhea, 9% have amenorrhea, 4.3% have vaginal
spotting, and 1.4% suffered from menorrhagia. Also among 128 married patients the bad obstetric outcome was reported
as follow: miscarriage (47.6%), stillbirth delivery (7.8%), preterm birth (5.4%) and neonate with congenital cerebral palsy
(0.7%). Interestingly 18 women suffered from premature ovarian failure and 20 women had primary infertility. Menstrual
cycle abnormalities among women with thyroid dysfunction were significantly associated with long duration of the
disease ≥5 years (OR=0.4; CI=, 0.2-0.8; P =0.016), co-morbidity (OR=9.0; CI=, 3.1-28.8; P =0.000), and poor
compliance to treatment (OR=0.2; CI=, 0.09-0.8; P =0.021). Thus polymenorrhea is the most predominant menstrual
cycle problem observed among Sudanese women with thyroid dysfunction. Menstrual cycle abnormalities among women
with thyroid dysfunction were significantly associated with long duration of the disease ≥5 years, co-morbidity and poor
compliance to treatment.