Title:Regulation of Eye Development by Protein Serine/Threonine Phosphatases-1 and -2A
Volume: 15
Issue: 10
Author(s): L. Wang, Y. Yang, X. -D. Gong, Z. -X. Huang, Q. Nie, Z. -F. Wang, W. -K. Ji, X. -H. Hu, W. -F. Hu and , L. -L. Gong, L. Zhang, S. Huang, R. -L. Qi, T. -H. Yang, Z. -G. Chen, W. -B. Liu, Y. -Z. Liu and D. W. -C. Li
Affiliation:
关键词:
丝氨酸/苏氨酸磷酸-1和2A号，眼部发育，晶状体变异，发展性细胞凋亡
摘要: The protein serine/threonine phosphatases-1 and -2A are major cellular phosphatases, playing a
fundamental role in organisms from prokaryotes to eukaryotes. They contribute to 90% dephosphorylation in
eukaryote proteins. In the eye, both phosphatases are highly expressed and display important functions in
regulating normal eye development. Moreover, they are implicated in pathogenesis through modulation of
stress-induced apoptosis. Here we review the recent progresses on these aspects.
