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Abstract
Obstructive Sleep Apnoea Syndrome (OSAS) and Chronic Obstructive Pulmonary Disease (COPD) are common respiratory diseases, associated with significant morbidity, worldwide. They frequently co-exist and the overlap syndrome is associated with greater hypoxia and hypercapnia in comparison with COPD or OSAS alone. Unfortunately, the overlap syndrome is still underdiagnosed and undertreated in clinical practice, leading to increased morbidity and mortality. The aim of this review is to present why OSAS is more prevalent among COPD patients, how to differentiate between the common sleep alteration in COPD and the overlap syndrome, the current screening, diagnostic and therapeutic approach of the overlap syndrome.
Keywords: Chronic obstructive pulmonary disease, obstructive sleep apnea, OLDOSA, overlap syndrome.
Current Respiratory Medicine Reviews
Title:Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea: A Two-Faced Janus
Volume: 11 Issue: 4
Author(s): Alexandru Corlateanu, Victor Botnaru, Alexander G. Mathioudakis, Victoria Sircu and Nikolaos Siafakas
Affiliation:
Keywords: Chronic obstructive pulmonary disease, obstructive sleep apnea, OLDOSA, overlap syndrome.
Abstract: Obstructive Sleep Apnoea Syndrome (OSAS) and Chronic Obstructive Pulmonary Disease (COPD) are common respiratory diseases, associated with significant morbidity, worldwide. They frequently co-exist and the overlap syndrome is associated with greater hypoxia and hypercapnia in comparison with COPD or OSAS alone. Unfortunately, the overlap syndrome is still underdiagnosed and undertreated in clinical practice, leading to increased morbidity and mortality. The aim of this review is to present why OSAS is more prevalent among COPD patients, how to differentiate between the common sleep alteration in COPD and the overlap syndrome, the current screening, diagnostic and therapeutic approach of the overlap syndrome.
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Cite this article as:
Corlateanu Alexandru, Botnaru Victor, G. Mathioudakis Alexander, Sircu Victoria and Siafakas Nikolaos, Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea: A Two-Faced Janus, Current Respiratory Medicine Reviews 2015; 11 (4) . https://dx.doi.org/10.2174/1573398X11666150915213406
DOI https://dx.doi.org/10.2174/1573398X11666150915213406 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Chronic obstructive pulmonary disease (COPD) from childhood to adulthood: from the past to the future
Chronic obstructive pulmonary disease (COPD) is one of the three leading causes of death worldwide, with a major prevalence in low- and middle-income countries, resulting in a high social and economic cost. It is a heterogeneous respiratory disease, treatable and preventable, that causes persistent and often progressive airway obstruction in ...read more
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