Title:A Population-Based Study of Cholesterol Measurements in the Oldest Old
Volume: 8
Issue: 3
Author(s): Charlotte Gils, Kaare Christensen and Mads Nybo
Affiliation:
Keywords:
Aging, cholesterol, age specific trends, requests behavior, risk factor, old age.
Abstract: Background: Effect of lipid-lowering treatment in the oldest old is a matter of debate as
there is no unequivocal evidence of statins being beneficial among the oldest. The need for cholesterol
measurements is therefore also questionable, but the frequency of cholesterol measurements in the
oldest old has not been described on a population basis. Therefore, the number of lipid measurements
in the period 2002-2012 was evaluated for people aged 85+ years.
Methods: The Laboratory Information System and the Population Register at Statistics Denmark were
used for retrieving data on people aged 85+ living on the Island of Funen. The development in trends for cholesterol
measurements was analysed in age groups of 5-years interval using linear regression analysis.
Results: A total of 30,424 persons with a cholesterol measurement entered the study. The total number of cholesterol
measurements increased by 246% during the observation period. The percentage of people having a cholesterol measurement
increased significantly (p < 0.001) from 2002 to 2012 for all groups except males over 100 years of age. The increase
was only due to requests from general practitioners, not from hospital units.
Conclusion: Despite the uncertainty regarding lipid-lowering treatment in the oldest old, the percentage of people having a
cholesterol measurement increased significantly during the study period. Whether this increase in cholesterol measurements
leads to increased prescription of lipid-lowering medication in this cohort and/or better outcomes warrants future
research.
