Title:Drug Likeness and Selective Functionalization of Quinoxalines
Volume: 12
Issue: 6
Author(s): Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery and Giuliano Cesar Clososki
Affiliation:
Keywords:
Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.
Abstract: In recent years, the pharmacological potential of quinoxalines has received vast interest
due to its many applications. This review centers on a critical overview of chemical diversity
and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies
for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.