Title:Recent Advances in Molecular Image-Guided Cancer Radionuclide Therapy
Volume: 16
Issue: 6
Author(s): Duo Gao, Xianlei Sun, Liquan Gao and Zhaofei Liu
Affiliation:
Keywords:
Image-guided therapy, molecular imaging, radionuclide therapy, treatment monitoring, tumor.
Abstract: Cancer-targeted radionuclide therapy is a promising approach for the treatment of a wide
variety of malignancies, especially those resistant to conventional therapies. However, to improve the
use of targeted radionuclide therapy for the management of cancer patients, the in vivo behaviors, dosimetry,
and efficacy of radiotherapeutic agents need to be well characterized and monitored. Molecular
imaging, which is a powerful tool for the noninvasive characterization and quantification of biological
processes in living subjects at the cellular and molecular levels, plays an important role in the
guidance of cancer radionuclide therapy. In this review, we introduce the radiotherapeutics for cancertargeted
therapy and summarize the most recent evidence supporting the use of molecular imaging to guide cancer
radionuclide therapy.
