Title:Stem Cell and Idiopathic Pulmonary Fibrosis: Mechanisms and Treatment
Volume: 10
Issue: 6
Author(s): Ming Liu, Dunqiang Ren, Dong Wu, Jian Zheng and Wenwei Tu
Affiliation:
Keywords:
Embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, pulmonary fibrosis, treatment.
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease resulting from multiplex causes.
Evidence indicates that stem/progenitor cells might play a key role in IPF pathogenesis and repair, which may provide
some novel potential strategies for the future treatment of IPF. In this review, we first summarize the current understanding
of the relationship between stem cells and IPF and then review the advancements made in recent clinical trials using
stem/progenitor cells, especially mesenchymal stem cells, in treating IPF and their interpretations.
