Abstract
The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.
Keywords: C-2 substituted adamantane, 4-(2-adamantyl)phenylalkylamines, antiproliferative activity.
Letters in Organic Chemistry
Title:Synthesis and Cytotoxicity of 4-(2-Adamantyl)phenylalkylamines
Volume: 12 Issue: 5
Author(s): Ioannis Papanastasiou, Stefanos Riganas, George B. Foscolos, Andrew Tsotinis, Samar A. Akhtar, Mohsin A. Khan, Khondaker M. Rahman and David E. Thursto
Affiliation:
Keywords: C-2 substituted adamantane, 4-(2-adamantyl)phenylalkylamines, antiproliferative activity.
Abstract: The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.
Export Options
About this article
Cite this article as:
Papanastasiou Ioannis, Riganas Stefanos, B. Foscolos George, Tsotinis Andrew, A. Akhtar Samar, A. Khan Mohsin, M. Rahman Khondaker and E. Thursto David, Synthesis and Cytotoxicity of 4-(2-Adamantyl)phenylalkylamines, Letters in Organic Chemistry 2015; 12 (5) . https://dx.doi.org/10.2174/157017861205150509202419
DOI https://dx.doi.org/10.2174/157017861205150509202419 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Are Bacteriocins Underexploited? NOVEL Applications for OLD Antimicrobials
Current Pharmaceutical Biotechnology Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part I: Xanthones, Quinones, Steroids, Coumarins, Phenolics and other Classes of Compounds
Anti-Cancer Agents in Medicinal Chemistry The Role of Melatonin in the Immuno-Neuro-Psychology of Mental Disorders
Recent Patents on CNS Drug Discovery (Discontinued) Nanostructured Lipid Carriers: New Insight for Cancer Therapy
Nanoscience & Nanotechnology-Asia Tissue-Based Approaches to Study Pharmacodynamic Endpoints in Early Phase Oncology Clinical Trials
Current Drug Targets Subject Index To Volume 6
Current Molecular Medicine Epigenetics in Necrotizing Enterocolitis
Current Pediatric Reviews Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent Update
Current Medicinal Chemistry Development of Genetic Testing for Breast, Ovarian and Colorectal Cancer Predisposition: A Step Closer to Targeted Cancer Prevention
Current Drug Targets Recent Patents on Live Bacteria and their Products as Potential Anticancer Agents
Recent Patents on Anti-Cancer Drug Discovery Influence of Vanin-1 and Catalytic Products in Liver During Normal and Oxidative Stress Conditions
Current Medicinal Chemistry Role of α7-Nicotinic Acetylcholine Receptor in Normal and Cancer Stem Cells
Current Drug Targets Interactions of Iron Oxide Nanoparticles with the Immune System: Challenges and Opportunities for their Use in Nano-oncology
Current Pharmaceutical Design Editorial (Hot Topic: Translational Medicine is Promoting Cross-talk of Interdiscipline)
Anti-Cancer Agents in Medicinal Chemistry An Insight into Purine, Tyrosine and Tryptophan Derived Marine Antineoplastic Alkaloids
Anti-Cancer Agents in Medicinal Chemistry The HOX Genes Network in Uro-Genital Cancers: Mechanisms and Potential Therapeutic Implications
Current Medicinal Chemistry Carcinoembryonic Antigen as a Target to Induce Anti-Tumor Immune Responses
Current Cancer Drug Targets Microparticles in Health and Disease: Small Mediators, Large Role?
Current Vascular Pharmacology Raf Inhibitors as Therapeutic Agents Against Neurodegenerative Diseases
CNS & Neurological Disorders - Drug Targets Molecular Targeting of Breast Cancer: Molecular Imaging and Therapy
Current Pharmaceutical Biotechnology