Title:Synthesis and Biological Activities of Organotin(IV) Complexes as Antitumoral and Antimicrobial Agents. A Review
Volume: 15
Issue: 5
Author(s): Syed Shoaib Ahmad Shah, Muhammad Ashfaq, Amir Waseem, M. Mehboob Ahmed, Tayyaba Najam, Salma Shaheen and Gildardo Rivera
Affiliation:
Keywords:
Agents, antimicrobial, antitumoral, synthesis, organotin(IV).
Abstract: Advances in the use of organotin(IV) compounds have gained relevant interest in both the
chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and
physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug
development as biologically active agents, and in other areas. This review focuses on recent progress
in the classical and convenient synthesis procedure, on their mechanism of action, and biological
activities as antitumoral and antimicrobial agents.